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134 results for “toxic effect”
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Research ArticleOpen accessIn the abstractCadmium Induced Changes in Metabolic Function of Mitochondrial Isolated from Potato Tissue (Solanum tuberosum L.)Chagra Ali, Djebar Mohammed Réda, Rouabhi Rachid, Berrebbah HouriaProblem statement: Cadmium is highly toxic at low concentrations, but the mechanism of its toxicity is still not understood particularly at the cellular and subcellular level. Approach: In this study we examined the effects of cadmium on the oxidophosphorylation properties of mitochondria isolated from potatoes. Results: Cadmium strongly disturbed the respiratory metabolism of mitochondria isolated especially in the transfer of … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 1 · 31 Aug 2009 · 7,842 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Study of the Essential Oils of Four Sudanese Accessions of Basil (Ocimum basilicum L.) Against Anopheles Mosquito LarvaeAzhari H. Nour, Salah A. Elhussein, Nour A. Osman et al.Problem statement: Certain basil essential oils were claimed to have a larvicidal activity towards mosquito's larvae. To test this claim the essential oils of four accessions of basil grown in Sudan were selected and tested for Anopheles larvae. Malaria is the major health problem in the Sudan and the whole country is now considered endemic, with varying degrees, about 35,000 … …American Journal of Applied Sciences, Vol. 6, Issue 7 · 31 Jul 2009 · 8,833 accessesView PDFCite
Research ArticleOpen accessIn the abstractBioaccumulation of Arsenic by FungiAdemola O. AdeyemiProblem statement: Arsenic is a known toxic element and its presence and toxicity in nature is a worldwide environmental problem. The use of microorganisms in bioremediation is a potential method to reduce as concentration in contaminated areas. Approach: In order to explore the possible bioremediation of this element, three filamentous fungi-Aspergillus niger, Serpula himantioides and Trametes versicolor were investigated for … …American Journal of Environmental Sciences, Vol. 5, Issue 3 · 30 Jun 2009 · 7,895 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of D- and L-Glucose and Mannitol on Retinal Capillary Cells: Inhibition by Nanomolar AminoguanidineYongxin Yu, Wei Li, Barbara Wojciechowski et al.Hyperglycemia may contribute directly to pericyte loss and capillary leakage in early diabetic retinopathy. To elucidate relative contributions of glycation, glycoxidation, sugar autoxidation, osmotic stress and metabolic effects in glucose-mediated capillary damage, we tested the effects of D-glucose, L-glucose, mannitol and the potentially protective effects of aminoguanidine on cultured bovine retinal capillary pericytes and endothelial cells. Media (containing 5 mM … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 4 · 31 Dec 2007 · 7,751 accessesView PDFCite
Research ArticleOpen accessIn the abstractSorbitol-Induced Diabetic-Like Retinal Lesions in Rats: Microscopic StudyGaber A. RamadanThe present study investigated the sorbitol toxicity on the retinas of normal albino rats and founded by the light microscope that intra-peritoneal injection of Sorbitol (10-mg/kg-body weight per day) for 24 weeks produced similar diabetic like retinal lesions in these rats. The retinopathic effects of sorbitol injection affect retinal microvessels, pigment epithelium, neural retina and glial cells. Cytoplasmic vacuolation of … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 2 · 30 Jun 2007 · 7,634 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessment of Genotoxic Activity of Para-nitrophenol in Higher Plant Using Arbitrarily Primed- polymerase Chain Reaction (AP-PCR)Mohamed R. EnanParanitrophenol is a common toxic environmental pollutant; the aim of this study was to evaluate the potential of the DNA fingerprinting by AP-PCR assay to detect the DNA damage in the common bean (Phaseolus vulgaris) exposed to different concentrations of paranitrophenol (4.0-720 nM). The changes occurring in the fingerprint patterns were likely to be the result of paranitrophenol-induced DNA damage. … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 2 · 30 Jun 2007 · 7,069 accessesView PDFCite
Research ArticleOpen accessIn the abstractControl of Anthracnose Caused by Colletotrichum musae on Curcuma alismatifolia Gagnep. Using Antagonistic Bacillus spp.Supuk Mahadtanapuk, Mondhon Sanguansermsri, Robert W. Cutler et al.Over 400 bacterial strains, isolated from leaf surfaces of Curcuma alismatifolia Gagnep. and hot springs in the Chiang Mai province of northern Thailand, were screened in vitro for antagonistic activity against Colletotrichum musae, an anthracnose fungus. Three isolates provided greater than 75% growth inhibition of the fungus in vitro and were identified as Bacillus licheniformis, B. amyloliquefaciens and B. subtilis. … …American Journal of Agricultural and Biological Sciences, Vol. 2, Issue 2 · 30 Jun 2007 · 9,013 accessesView PDFCite
Research ArticleOpen accessIn the abstractCharacteristics of Nitrogen Removal from Old Landfill Leachate by Sequencing Batch Biofilm ReactorLong Tengrui, Anas F. Al-Harbawi, Lin Ming Bo et al.Municipal landfill leachate is a high strength wastewater characterized by high concentrations of organics and ammonia and potentially containing toxic materials. The paper reports the results of a laboratory scale investigation aimed at evaluating the effectiveness of mature municipal landfill leachate treatment by a biological stage (used SBBR as a biological treatment) to study the nitrogen removal capabilities for treatment … …American Journal of Applied Sciences, Vol. 4, Issue 4 · 30 Apr 2007 · 8,046 accessesView PDFCite
Research ArticleOpen accessIn the abstractPharmacological Screening of Arceuthobium oxycedri (Dwarf Mistletoe) of Juniper Forest of PakistanMudassir Asrar Zaidi, Ahsan Huda, Sidney A. CrowThe local population of Balochistan, Pakistan considers the Juniperus excelsa an important medicinal plant. The species is facing a grave threat by a parasitic and epiphytic angiosperm, dwarf mistletoe, Arceuthobium oxycedri (DC) M. Bieb (Viscaceae). The methanolic extract of A. oxycedri was studied for its chemical composition and biologically active compounds for the first time. The extract was assayed for … …OnLine Journal of Biological Sciences, Vol. 6, Issue 2 · 31 Dec 2006 · 7,004 accessesView PDFCite
Research ArticleOpen accessIn the abstractRetinoids Chemosensitize Ovarian Cancer Cell Lines to Cisplatin Independent of Nuclear Receptors and p53Suresh Guruswamy, Doris M. BenbrookTreatment of ovarian cancer with cisplatin-based chemotherapy is highly toxic and is often followed by cancer recurrence. Repeated treatments with cisplatin frequently result in the development of resistance to this drug. Drugs with low toxicity that could enhance the tumor cell killing effects of cisplatin could potentially reduce the toxicity and enhance the efficacy of cisplatin. The mechanism of cell … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2006 · 6,962 accessesView PDFCite