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139 results for “response function”

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Research ArticleOpen accessIn the abstractCo-Inhibitory Molecule Programmed Death-1 and its Ligands: A New Alternative Therapy for Human Immunodeficiency Virus Infection?A. Leon-Flores, P. Del Rio, G. Reyes-TeranChronic viral infections are characterized by the up-regulation of a set of immunomodulatory receptors. The over-expression of co-inhibitory molecules on T cells leads to a dysfunctional T cell response with an "exhausted" phenotype. Programmed Death-1 (PD-1) is a molecule that exerts an inhibitory signal on the T cell receptor when it binds to the PD-L1 or PD-L2 ligands present on … …American Journal of Infectious Diseases, Vol. 8, Issue 4 · 28 Dec 2012 · 6,962 accessesView PDFCite
Research ArticleOpen accessIn the abstractInnate, Adaptive and Intrinsic Immunity in Human Immunodeficiency Virus InfectionSuneth S. Perera, Nitin K. SaksenaThe first line of defence of the innate immune system functions by recognizing highly conserved sets of molecular structures specific to the microbes, termed pathogen-associated molecular patterns, or PAMPs via the germ line-encoded receptors Pattern-Recognition Receptors (PRRs). In addition to the innate immune system, the vertebrates have also evolved a second line of defence termed adaptive immune system, which uses … …American Journal of Infectious Diseases, Vol. 8, Issue 3 · 27 Nov 2012 · 9,723 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuroprotective Effect against Cerebral Ischemia of Passiflora foetidaJintanaporn Wattanathorn, Natcha Sattroopinat, Terdthai Tong-Un et al.Problem statement: Although cerebral ischemia induced by stroke has been regarded as the important problem worldwide, the therapeutic efficacy is still inadequate. Since the free radicals are implicated in the pathophysiology of cerebral ischemia, the prophylactic protection against stroke with neuroprotective agent possessing antioxidant effect has gained much attention. Therefore, this study was designed to determine whether the alcoholic extract … …American Journal of Applied Sciences, Vol. 9, Issue 4 · 16 Feb 2012 · 8,242 accessesView PDFCite
Research ArticleOpen accessIn the abstractFunctional Neuroimaging in Dementia and other Amnesic Disorders: A Radiological ReviewLeonardo Caixeta, Renata Teles Vieira, Sergio Machado et al.Problem statement: The structural and functional neuroimaging have much to contribute to the cognitive neuroscience. Approach: We describe a radiological review of the major dementia syndromes and Mild Cognitive Impairment (MCI), included Alzheimer's disease, Lewy body dementia, Vascular dementia, Front temporal Lobar degeneration, Dementia associated with parkinsonism and other amnesic syndromes. Results: The different syndromes and diseases presenting with dementia … …Neuroscience International, Vol. 2, Issue 1 · 23 Nov 2011 · 7,495 accessesView PDFCite
Research ArticleOpen accessIn the abstractLow Power Multiplier Design Using Latches and Flip-FlopsC. N. Marimuthu, P. ThangarajProblem statement: Power dissipation is designated as critical parameter in modern VLSI design field. In VLSI implementation low power concept is necessary to meet Moore’s law and to produce consumer electronics with more back up and less weight. To save significant power consumption of a VLSI design, it is a good direction to reduce its dynamic power which is the … …Journal of Computer Science, Vol. 6, Issue 10 · 30 Jul 2010 · 7,372 accessesView PDFCite
Research ArticleOpen accessIn the abstractBioInfoPhysics Models of Neuronal Signal Processes Based on Theories of Electromagnetic FieldsKang Cheng, Chang H. ZouProblem statement: The aphasia is one of human language and action related brain associative diseases. The mechanisms of the diseases and the brain association are still unclear. In this study, we proposed our models of the neuronal signal processes, in a view of BioInforPhysics, to understand the mechanisms. Approach: Our models are based on today’s solidest Electromagnetic Fields (EMF) theoretic … …Neuroscience International, Vol. 1, Issue 1 · 10 Feb 2010 · 6,898 accessesView PDFCite
Research ArticleOpen accessIn the abstractTask Load Balancing Strategy for Grid ComputingB. Yagoubi, Y. SlimaniWorkload and resource management are two essential functions provided at the service level of the Grid software infrastructure. To improve the global throughput of these environments, effective and efficient load balancing algorithms are fundamentally important. Most strategies were developed in mind, assuming homogeneous set of resources linked with homogeneous and fast networks. However for computational Grids we must address main … …Journal of Computer Science, Vol. 3, Issue 3 · 31 Mar 2007 · 7,605 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn vitro Activation of Human and Rat Lymphocyte and Macrophage Functions by NorepinephrineRicardo Gomez-Flores, Diana Caballero-Hernandez, Richard J. Weber et al.Norepinephrine (NE) has been associated not only with increasing blood pressure, atherosclerosis, heart disease, and other life threatening conditions, but also with altering immune responses by influencing leukocyte functions. In the present study, we evaluated the in vitro effects of NE on rat thymic lymphocyte and human peripheral blood mononuclear cells (HPBMC) functions. We observed that NE marginally, but significantly … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 7,075 accessesView PDFCite
Literature ReviewOpen accessAll words, across the recordMitochondrial Dysfunction Model in the Pathogenesis of Inflammatory Response Development in ObesityAlexander Blagov, Varvara Orekhova et al.Obesity is one of the growing problems of modern society. Although currently used methods of treating obesity, including diet, exercise, and drug therapy, have shown their applicability to more effectively combat obesity, an understanding of the pathogenesis of this disease is required. One of the insufficiently studied factors in the pathogenesis of obesity is the development of mitochondrial dysfunction understanding … …OnLine Journal of Biological Sciences, Vol. 24, Issue 1 · 19 Nov 2023 · 4,933 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordDetermination of the Probiotic Potential and Metabolic Function of Lactobacillus Strains for Healthy Calf RearingRaya Myktybayeva, Serkan Özkaya, Elif Rabia Şanlı et al.This research investigstes the impact of probiotic supplementation on the growth performance, health status, and physiological traits in Holstein calves. A total of thirty calves were randomly divided into three experimental groups: a control group and two treatment groups receiving probiotics at doses of 1 g/10 kg and 1.5gt/10 kg live weight. Key indicators, including Live Weight (LW), Body Measurements … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 23 Jul 2025 · 3,626 accessesView PDFCite