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Research ArticleOpen accessIn the abstractHuman Adipose Stem Cells in Collagen on Angiogenesis Process of Burn Healing in Rat Model: Its Number of Blood VesselsLuluk Yunaini, Puji Sari, Dwi Pratami Septiara et al.Angiogenesis in the burn wound healing process is important. The application stem cell therapy in burn wound problem is expected to increase formation of new blood vessel so that the distribution of oxygen and nutrients working well. The purpose of this study was to known effect of human Adipose Derived Stem Cell (hADSC) in collagen gel on the average number … …OnLine Journal of Biological Sciences, Vol. 19, Issue 1 · 7 Jan 2019 · 7,605 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Novel Glucan-Sulforaphane Combination Stimulates Immune Response to Influenza in Mouse ModelVetvicka Vaclav, Vetvickova JanaInfluenza remains a serious health problem and causes approximately 500,000 deaths world-wide. With current available treatments offering neither dependable protection nor a rapid cure, many have focused their attention to alternative treatments. The aim of this study was to evaluate the possible effect of a novel maitake glucan-sulforaphane combination on immune response against influenza challenge in mice. We evaluated the … …American Journal of Immunology, Vol. 12, Issue 2 · 3 Aug 2016 · 7,935 accessesView PDFCite
Research ArticleOpen accessIn the abstractCpG Oligodeoxynucleotides Debate the Damaging Action of Cisplatin on Immune Cell DNA: A PCR Array Application on Repair Genes ExpressionNaglaa Fathy Alhusseini, Amal Abo El-Fadl, Shabaan Hemada et al.Synthetic Oligodeoxynucleotides (ODN) expressing CpG motifs (CpG-ODN) mimic the immunostimulatory activity of bacterial DNA and are commonly used to activate Toll Like Receptor 9 (TLR9) for therapeutic applications. CpG-ODN can counteract the activity of DNA-damaging chemotherapy and radiation therapy on immune cell and enhance immunity in preclinical mouse models. We hypothesized that these actions of CpG-ODN on immune cells are … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 3 · 27 Jul 2016 · 7,628 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnalgesic and Anti-inflammatory Activity of Euphorbia antiquorum LinnBanibrata Das, Samina Alam, Rajib Bhattacharjee, Biplab Kumar DasEuphorbia antiquorum (L.) is used as traditional medicine for various ailments in Bangladesh. But the scientific basis for its use especially in pain and inflammation remains largely unknown. Therefore, the present study was designed to evaluate analgesic and anti-inflammatory effect of the aqueous ethanolic extract of the whole plant. The analgesic activity was evaluated by hot plate, acetic acid induced … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 2 · 27 Aug 2015 · 9,213 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunomodulatory and Antioxidant Properties of Kaurenoic Acid on Macrophages of BALB/c in VitroJuliana Aparecida Macri, Suelen Santos da Silva, Milena Menegazzo Miranda et al.Kaurenoic acid has been displaying anti-inflammatory effect described in different models. However, the per se immunomodulatory effects of kaurenoic acid remain to be investigated. Thus, the immunomodulatory and antioxidant effects of kaurenoic acid were investigated in vitro on peritoneal macrophages from BALB/c mice. Kaurenoic acid induced per se the production of pro-inflammatory cytokines such as TNFα, IL-1β and IFN-γ while … …American Journal of Immunology, Vol. 10, Issue 4 · 16 Feb 2015 · 7,885 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Inflammatory, Analgesic and Antioxidant Activities of Allophylus Cobbe LeavesPreeti Jain, Md. Selim Hossain, Kaniz Fatema et al.Allophylus cobbe L. Raeuschel (Family-Sapindaceae) is a medicinal plant used traditionally for the treatment of various health risks like pain, inflammation, ulcers and wounds in Bangladesh. This study determined the polyphenolic compounds and evaluated the analgesic, anti-inflammatory and antioxidant effects of the ethanol extract of Allophylus cobbe leaves. High Performance Liquid Chromatography (HPLC) analysis was used to determine the polyphenolic … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 27 Jan 2015 · 8,155 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Exercise Prior or After Ischemia on the Density of Neurons and Astrocytes in the Brain of RatsLaila Cristina Moreira Damázio, Raphael Teixeira Rocha Melo, Maira de Castro Lima et al.The aim of this study was to analyse the density of astrocytes and neurons in the motor areas of the cortex, striatum and hippocampus of rats that performed exercise before or after cerebral ischemia. A total of 36 Wistar rats were separated into two groups: One that was subjected to Middle Cerebral Artery Occlusion (MCAO) and the other that underwent … …Neuroscience International, Vol. 5, Issue 2 · 14 Jan 2015 · 7,350 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Effect of Galactomannan Extracted from Iraqi Lycium barbarum L. Fruits against Alloxan-Induced Diabetes in RatsAdnan J.M. Al-FartosyLycium barbarum L. (Solanaceae) is widely used in Iraqi Ayurvedic medicine for the treatment of diabetes mellitus. The present investigation was done to evaluate the effects of polysaccharide (galactomannan) from Lycium barbarum L. Fruits (GLBF) on serum blood glucose, serum lipid profile and lipid peroxidation and antioxidant defence system in liver and kidney of alloxan-induced diabetic rats. GLBF was found … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 2 · 15 Dec 2014 · 7,657 accessesView PDFCite
EditorialOpen accessIn the abstractNanotechnology: Engineering Materials for a Better 21st CenturyMeng Qiao, Xiyun Liu, Lei ZhangToday, we are living in the midst of a technological revolution, where nanotechnology is demonstrating a greater commitment to make people’s everyday lives better. The aim of nanotechnology is to create new materials with desired properties by engineering their nanoscale structures and components. One of the most important impacts of nanotechnology is in medical diagnosis and treatment. Cardiovascular diseases such … …Current Research in Nanotechnology, Vol. 5, Issue 1 · 26 Nov 2014 · 8,743 accessesView PDFCite
Research ArticleOpen accessIn the abstractSTUDIES ON GASTROINTESTINAL EFFECTS OF DESMODIUM VELUTINUM: A TRADITIONAL REMEDY FOR DIARRHEAA. C. Ezike, P. A. Akah, C. O. Okoli et al.The gastrointestinal and antibacterial properties of dichloromethane: Methanol extract (DVE) and fractions (DVHF, DVDF and DVMF) from Desmodium velutinum Willd. DC. (Fabaceae) leaves were investigated. The extract and fractions significantly (p 5g kg-1 in mice. Results demonstrated that D. velutinum leaf possesses gastrointestinal antimotility and antispasmodic effects and mild antibacterial and gastroprotective activities. …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 12 Mar 2014 · 7,953 accessesView PDFCite