Research ArticleOpen accessIn the abstractMetabolic Markers of Insulin Resistance in Feline Hypertrophied Myocardium. Insulin Resistance in Heart FailureOleinikov Dmitrii ArkadievichInvestigation of myocardial tissue concentration of ATP, glucose transporters 1 and 4, pyruvate dehydrogenase, hexokinase 2, insulin receptor and adropin proteins, determining metabolic changes and possible insulin resistance in feline myocardium with hypertrophic phenotype. This is the pilot study for metabolic markers determination. Eighteen cats were studied, divided into 3 groups: Without cardiac disease (n = 5), cats with hypertrophic … …American Journal of Animal and Veterinary Sciences, Vol. 15, Issue 4 · 13 Nov 2020 · 6,332 accessesView PDFCite
Research ArticleOpen accessIn the abstractComprehending the Environmental and Household Determinants of Jaundice Prevalence in Western NepalUttam Paudel, Krishna Prasad PantPersuasive but scanty evidences from literature claim that climate change is linked with neonatal and adult Jaundice prevalence, especially in underdeveloped countries. This paper explored major environmental and household characteristics attributable to Jaundice prevalence in western Nepal. Cross-sectional dataset obtained from household survey are employed to obtain the results from probit regression model, adequately leveled with an econometric theory. The … …American Journal of Applied Sciences, Vol. 17, Issue 1 · 19 Feb 2020 · 7,897 accessesView PDFCite
Research ArticleOpen accessIn the abstractDoes Iron Modulate Cytokine Production by Desferrioxamine Treated Mononuclear Cells?Hanna Bessler, Meir DjaldettiIron is an essential element for maintaining the normal function of cellular and multicellular organisms and it is closely associated with inflammation and immunity. Macrophages and lymphocytes play an important role in its homeostasis. Hereby we have evaluated cytokine production by iron depleted and iron supplemented human peripheral blood mononuclear cells (PBMC) from healthy adult donors. Non-stimulated or stimulated PBMC … …OnLine Journal of Biological Sciences, Vol. 18, Issue 1 · 7 Jan 2018 · 6,849 accessesView PDFCite
Research ArticleOpen accessIn the abstractSequence Analysis of VP2 Gene of the Parvoviruses Isolated from Fecal Samples of Domestic Cats in Tehran, IranNegin Jahanbin, Shahram Jamshidi, Omid MadadgarPanleukopenia is a viral enteritis of high mortality rate in Feline population. It is caused by a small single-stranded DNA virus, belonging to the Family Parvoviridae, called Feline Panleukopenia Virus (FPV). Parvoviruses are capable of adapting to new hosts and can simply mutate like RNA viruses, resulting in the emergence of different strains with antigenic changes. Unlike the original Canine … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 4 · 28 Oct 2017 · 7,696 accessesView PDFCite
EditorialOpen accessIn the abstractIs Rerum® the New Coley's Vaccine?Marco RuggieroColey's Vaccine and Cancer Immunotherapy Dr. William B. Coley is credited for having been the first to translate the observation of an association between bacterial infections, high fever and cancer remission into a successful cancer treatment. However, it is worth noting that such an association dates back to at least one century before Coley's times; as Wiemann and Starnes from … …American Journal of Immunology, Vol. 13, Issue 2 · 31 May 2017 · 12,285 accessesView PDFCite
Research NotesOpen accessIn the abstractFunctionalization Strategies for Antibodies: Lessons LearnedChristian Schmidt, Martin Geyer, Jörg Bohrisch et al.Precious little is known about useful functionalization strategies of antibodies that will not impair either reactivity or specificity of this valuable reagent. We used an experimental approach to demonstrate our own experience with published protocols. The conjugates obtained were then tested with regard to their performance against commercially available detection kits. Our results are then viewed in light of published … …American Journal of Immunology, Vol. 13, Issue 2 · 4 May 2017 · 7,595 accessesView PDFCite