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142 articles for “Cardiovascular”
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Research ArticleOpen accessIn the abstractChronic Kidney Disease-Mineral Bone Disoder: Fibroblast Growth Factor-23 and Phosphate MetabolismWisit Cheungpasitporn, Pongsathorn Kue-A-Pai, Patompong Ungprasert et al.Chronic Kidney Disease (CKD) is a growing epidemic in the United States. There are hormonal changes that develop long before the mineral changes in patients with CKD occur. Increased Parathyroid Hormone (PTH) levels first become evident when the estimated Glomerular Filtration Rate (eGFR) is below 60 mL/min/1.73m2. High serum phosphate stimulates the secretion of the Fibroblast Growth Factor 23 (FGF-23) … …Current Research in Medicine, Vol. 4, Issue 1 · 4 May 2013 · 6,882 accessesView PDFCite
Research ArticleOpen accessIn the abstractAlcohol Consumption and its Correlates Among Residents of Mining Town, Kitwe, Zambia: 2011 Population Based SurveyCosmas Zyaambo, Olusegun Babaniyi, Peter Songolo et al.Alcohol consumption is a risk factor for non-communicable diseases such as cardiovascular diseases, liver cirrhosis and cancers. It has also been associated with risky sexual behaviors, hence, attributed as a factor in the increase of HIV incidence and prevalence. A cross sectional study was conducted using a modified World Health Organizations Global Non Communicable Diseases (NCD) Surveillance Initiative NCD-STEPs 1and … …Current Research in Medicine, Vol. 4, Issue 1 · 29 Jan 2013 · 8,051 accessesView PDFCite
Research ArticleOpen accessIn the abstractRole of Galphaq Containing Protein in Immune RegulationYuan Liu, Lu Gan, Guixiu ShiG proteins, one of the most important transmembrane signal transducers, contain four subfamilies. Gαq is the α subunit of Gq protein subfamily. The Gαq containing protein initially attracted attention for its physiological significance is in cardiovascular system. In recent years, its role in immune regulation has been indicated. Studies domenstrated that Gαq plays crucial role in regulating both innate and … …American Journal of Immunology, Vol. 8, Issue 4 · 18 Oct 2012 · 7,421 accessesView PDFCite
Research ArticleOpen accessIn the abstractMethylenetetrahydrofolate Reductase (677C/T) Polymorphism in Myocardial Infarction and HypertensionHatem Al-Kordy Amin, Hanaa Fahmy Abdel Aziz, Ola Farouk Leheta, Hanan KamalHyperhomocysteinemia is a well-established risk factor for cardiovascular disease and hypertension. This study aimed to assess the MTHFR gene polymorphisms (677C/T) as a potential genetic risk factor for hypertension and Myocardial Infarction (MI) in Egypt. Myocardial infarction and hypertensive diagnosed patients were divided into two groups; first comprised 50 patients aged 45 years and a third control group comprised 84. … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 3 · 20 Sep 2012 · 8,138 accessesView PDFCite
Research ArticleOpen accessIn the abstractState of the Art: Practical Approach for Diagosis of Pulmonary EmbolismNarat Srivali, Supawat Ratanapo, Promporn Suksaranjit et al.Pulmonary embolism is one of the leading causes of cardiovascular related death beside myocardial infarction and stroke. Contrary to stroke and myocardial infarction, diagnosis of pulmonary embolism is considered to be much more difficult and complicated compare with the treatment once diagnosis is confirmed. Multiple diagnostic studies including clinical scoring, serum biomarker and diagnostic imaging were developed to help clinician … …Current Research in Medicine, Vol. 3, Issue 2 · 1 Aug 2012 · 7,311 accessesView PDFCite
Research ArticleOpen accessIn the abstractElevated Th17 and IL-23 in Hypertensive Patients with Acutly Increased Blood PressureJunxian Wang, Jianying Chen, Can Chen et al.Problem statement: Many severe cardiovascular complications such as stroke and heart attack can result from acutely increased blood pressure in patients with hypertension. The underlying mechanisms remain unclear despite of extensive study. To characterize the inflammatory mechanisms in hypertensive patients with acute blood pressure increase, we tested circulating Th17 levels, IL-23R expression and plasma levels of IL-17 and IL-23 in … …American Journal of Immunology, Vol. 8, Issue 2 · 21 May 2012 · 7,920 accessesView PDFCite
Research ArticleOpen accessIn the abstractVitamin C Alleviates Chronic Chlorpyrifos Induced Alterations in Serum Lipids and Oxidative Parameters in Male Wistar RatsS. F. Ambali, M. Shittu, J. O. Ayo et al.Problem statement: Although the increase incidence of cardiovascular diseases, obesity and diabetes mellitus has been attributed to changing life style, the role of environmental contaminants is currently being given considerable attention. Pesticides, including Organophosphate (OP) insecticides are one of the most pervasive environmental contaminants that are deliberately released into the environment. Chlorpyrifos (CPF), a widely used OP insecticide has been … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 4 · 21 Feb 2012 · 7,578 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnticonvulsant Effect of Pitavastatin in Mice Induced by PentylenetetrazoleKhayatnouri MirhadiProblem statement: The 3-Hydroxy-3-Methylglutaryl-CoA (HMG-CoA) reductase inhibitors (statins) have been unequivocally shown to reduce cardiovascular morbidity and mortality by their lipid-lowering actions. It has been suggested that statins appear to have therapeutic benefits in diseases that are unrelated to elevated serum cholesterol levels. The aim of this study was to evaluation the effect of intraperitoneally injection of different doses of … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 11 Jan 2012 · 7,511 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Intraperitoneally Injection of Different Doses of Lovastatin on Pain and Inflammatory Response Induced by Formalin in MiceKhayatnouri MirhadiProblem statement: The 3-Hydroxy-3-Methyl Glutaryl-CoA (HMG-CoA) reductase inhibitors (statins) have been unequivocally shown to reduce cardiovascular morbidity and mortality. Their lipid-lowering actions are by reversible and competitive inhibition of the enzyme HMG-CoA reductase, a precursor of cholesterol. It has been suggested that statins appear to have therapeutic benefits in diseases that are unrelated to elevated serum cholesterol levels, such as … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 11 Jan 2012 · 7,685 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Nifedipine on Dichlorvos-Induced Seizure in MiceKhayatnouri MirhadiProblem statement: Dichlorvos a synthetic organophosphate poisons is the property of insecticide. These toxins as insecticides in agriculture and medicine for animals and the destruction of ectoparasites can be used. Studies have shown that Dichlorvos creation seizure effects in different animals. Nifedipine, dihydropyridine calcium channel blockers, widely used for treatment of cardiovascular diseases. Studies have shown that the calcium channel … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 2 · 17 Sep 2011 · 8,059 accessesView PDFCite