3 results for “Ying-Ray Lee”

Research ArticleOpen accessIn the author namesSignaling Pathways Involved In Dengue-2 Virus Infection Induced RANTES OverexpressionYing-Ray Lee, Huan-Yao Lei, Shun-Hua Chen et al.Dengue viruses participate in liver inflammation by inducting the expression of various chemokines including Regulated on Activation Normal T-cell Expressed and Secreted (RANTES). However, the underlying signaling remains unknown. Here, we reveal that Ras, Raf-1 and three mitogen-activated protein kinases (MAPKs) p38, extracellular signal-regulated kinase (Erk), and c-jun-NH2-terminal kinase (JNK) can be activated or phosphorylated in dengue-2 virus infected hepatocyte … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,173 accessesView PDF Cite

Research ArticleOpen accessIn the author namesCorrelation of IFN-Inducible Protein 10 Levels in Sera with Disease Severity and Clinical Outcome of the Dengue PatientsYing-Ray Lee, Nguyen-Thanh Hung, Ching-Chuan Liu et al.Dengue Virus (DV) infection may cause life-threatening Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS). Although many cytokines involved in the pathogenesis of DHF/DSS have been reported, the expression status of IFN-inducible protein-10 (IP-10) in dengue patients is still unknown. This is the first report to unravel that IP-10 level was significantly elevated in the sera of Dengue Fever … …American Journal of Infectious Diseases, Vol. 4, Issue 1 · 31 Mar 2008 · 7,051 accessesView PDF Cite