4 results for “S. P. Thakker”

Research ArticleOpen accessIn the author namesCardioprotective Effect of Cucumis trigonus Roxb on Isoproterenol-Induced Myocardial Infarction in RatB. S. Thippeswamy, S. P. Thakker, S. Tubachi et al.Problem statement: Cucumis trigonus Roxb fruit is used for various ailments in Indian traditional system of medicine such as anthelmintic, liver tonic, cardio tonic, appetizer, expectorant and intellect promoting. However, there is lack of information regarding the effect of Cucumis trigonus on the cardiac changes associated with ISO induced myocardial infarction. Approach: The present study was designed to evaluate the … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 2 · 30 Jun 2009 · 11,555 accessesView PDF Cite

Research ArticleOpen accessIn the author namesNaloxone benzoylhydrazone activates Extracellular Signal-Regulated Protein Kinases and modulates Nociceptin Opioid Peptide Receptor activityDeepak R. Thakker, Ghazi F. Altememi, Chitra D. Mandyam et al.Naloxone benzoylhydrazone (NalBzoH) is often used as a nociceptin opioid peptide (NOP) receptor antagonist. However, NalBzoH is also a mixed μ antagonist/κ and δ opioid agonist and its actions at the NOP receptor range from an antagonist to partial agonist, depending on the effector response/system studied. We now report that NalBzoH activates endogenously expressed κ3 opioid, but not NOP, receptors … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 2 · 30 Jun 2007 · 7,554 accessesView PDF Cite