5 results for “Asmaa M. Fahim”

Research ArticleOpen accessIn the author namesComputer Aid Screening for Potential Antimalarial Choroquinone Compounds as Covid 19 Utilizing Computational Calculations and Molecular Docking StudyAsmaa Aboelnaga, Asmaa M. Fahim, Taghreed H. EL-SayedClick reaction of 4,7-dichloroquinoline (1) with thiosemicarbazide (2) to afford the corresponding 2-(7-chloroquinolin-4-yl)thiosemicarbazide (3) utilized ultrasonic irradiation which can cyclized easily with ethylacetoacetate to give the 3-(7-chloroquinolin-4-ylamino)-tetrahydro-6-methyl-2-thioxopyrimidin-4(1H)-one (4) via nucleophilic substitution reaction. The synthesized compounds was examined in vitro antimalarial activity with IC50 = 11.92, 25.37 μg/mL against chloroquinone drug. Furthermore, the theoretical investigation of most active compounds CQT and … …OnLine Journal of Biological Sciences, Vol. 20, Issue 4 · 30 Nov 2020 · 6,570 accessesView PDF Cite

Research ArticleOpen accessIn the author namesMicrowave Assisted Regioselective Synthesis and Biological Evaluation of Pyrano[2,3-c]Pyridine Derivatives Utilizing DMAP as a CatalystAsmaa M. FahimRegioselective facile production of pyrano[2,3-c]pyridine through multicomponent reaction of aromatic aldehydes, ethyl cyano acetate or malononitrile and C-H activated compound of 3-hydroxy picolinic acid in the occurrence of smaller amount of DMAP catalyst utilizing microwave apparatus, which is green and simple environmentally with high yield, recyclability catalyst. Totally the products were partitioned for antimicrobiogical action; it was detected that were … …OnLine Journal of Biological Sciences, Vol. 17, Issue 4 · 14 Dec 2017 · 8,022 accessesView PDF Cite

Research ArticleOpen accessIn the author namesFACILE SYNTHESIS OF IN-VIVO INSECTICIDAL AND ANTIMICROBIAL EVALUATION OF BIS HETEROCYCLIC MOIETY FROM PET WASTEAsmaa Mahmoud Fahim, El Sayed Mohamed Yakout, Galal Abd ElMohein NawwarRecycling of Plastic Solid Waste (PSW) using green tool such as solar energy which used for degradation of plastic solid bottles (PET) to afford terepthalic acid which estrified using butanol/H2SO4 to afford dibutyl terephthalate as a starting material which has been chemically modified to yield new bis (1,2,4-triazole-3-thiol) 5, 1,3,4-oxadiazole 6, 8, 15, 1,3-thiazolidine 9, 1 H-pyrazole 10, 11 and … …OnLine Journal of Biological Sciences, Vol. 14, Issue 3 · 21 Aug 2014 · 7,379 accessesView PDF Cite