Research ArticleOpen accessEvery word in the titleTranscriptomic Analysis of the Erythritol High-Yielding Mutant Strain Yarrowia lipolytica Y44Xiaojie Ren, Heng Ban, Chao Huang et al.RNA-seq technique was used to analyze the transcriptomics of Yarrowia lipolytica control strain Po1g, an erythritol-producing natural isolate Yarrowia lipolytica Y 22 and an erythritol high-yielding mutant strain Y44 derived from Y 22. Functional annotation of genes and classification of metabolic pathways were carried out to identify Differentially Expressed Genes (DEGs). These DEGs were classified into related metabolic pathways to … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 4 · 20 Dec 2021 · 6,115 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Postgenomic Era: Transcriptomic as the New Paradigm of LifeBruno Giardina, Marcella Renis, Vito Latora, Salvatore MusumeciNow that complete genome sequences are available for a variety of organism, the elucidation of single gene function involved in the metabolism, includes necessarily a better understanding of the cellular responses on all levels of gene products, mRNA, proteins and metabolites. Such knowledge’s growth is essential since the observable properties of living organisms, so called phenotypes, are the results of … …OnLine Journal of Biological Sciences, Vol. 6, Issue 1 · 30 Jun 2006 · 6,822 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIntegrated Analysis of Transcriptomic and Metabolomic Responses in Rice Resisting False SmutYanmin Yu, Haiying Liu, Hongtao Wu et al.Rice false smut, caused by Ustilaginoidea virens, is an important fungal disease that reduces both grain yield and quality. To dissect the molecular basis of resistance, we combined transcriptome sequencing and metabolite profiling in resistant and susceptible rice cultivars. Transcriptome sequencing revealed more than 8,500 genes with altered expression patterns after infection, while metabolite profiling detected over 700 significantly changed … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 3 · 27 Aug 2026 · 1,057 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleTRANSCRIPTOMIC CHANGES IN RUMINAL TISSUE INDUCED BY THE PERIPARTURIENT TRANSITION IN DAIRY COWSLouis Dionissopoulos, Ousama AlZahal, Michael Alexander Steele et al.To understand how the capacity for fat metabolism (uptake, synthesis, modification) changes in rumen epithelia immediately before and after onset of lactation in dairy cows, rumen fluid Short Chain Fatty Acid (SCFA) concentrations and mRNA expression profiles of rumen epithelia was determined in twelve Holstein dairy cows at three weeks prior to calving (wk -3, n = 12), one week … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 1 · 13 Jan 2014 · 7,501 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEpigenetic Regulation of Extracellular Matrix Remodeling in Skin Aging: Mechanisms and InteractionsJiguang Yang, Yusong Shi, Xiaoqing YanSkin aging results from complex interactions between genetic factors, environmental stressors, and epigenetic modifications that regulate extracellular matrix (ECM) remodeling. Accumulation of senescent cells impairs tissue regeneration through mechanisms including telomere shortening, reactive oxygen species accumulation, and ultraviolet (UV) radiation exposure. While epigenetic pathways regulate skin homeostasis, regeneration, and senescence, the specific epigenetic changes occurring during UV exposure, chronological aging, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,458 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Construction of Two and Three Dimensional Molecular Models for the miR-31 and Its Silencer as the Triple Negative Breast Cancer BiomarkersArli Aditya ParikesitThe Triple Negative Breast Cancer (TNBC) is considered as the most difficult Breast Cancer type to be medicated. So far, the acceptable medication and diagnostics measure are based upon the proteomics-world view, especially with utilizing the natural products and their derivatives as drug candidates. However, as the transcriptomics-studies are getting more advanced, the research on non-coding (nc)RNA is being considered … …OnLine Journal of Biological Sciences, Vol. 18, Issue 4 · 18 Oct 2018 · 7,772 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Role of Ganoderma lucidum Polysaccharides Against Stress Induced by Heavy Metals in Caenorhabditis elegansHuixiu Ma, Dehui Dai, Guicai Chen, Weilian HuAli, H., Khan, E., & Ilahi, I. (2019). Environmental Chemistry and Ecotoxicology of Hazardous Heavy Metals: Environmental Persistence, Toxicity, and Bioaccumulation. Journal of Chemistry, 2019, 6730305. https://doi.org/10.1155/2019/6730305 Aljerf, L., & Aljerf, N. (2023). Food products quality and nutrition in relation to public. Balancing health and disease. Progress in Nutrition, 25(1), e2023024. https://doi.org/10.23751/pn.v25i1.13928 Aljerf, L., Williams, M., Ajong, A. B., Onydinma, … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 2 · 18 May 2024 · 6,947 accessesView PDFCite