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17 articles for “tissue scaffold”
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Research ArticleOpen accessEvery word in the titleComposite Scaffolds for Bone Tissue EngineeringMin WangBiomaterial and scaffold development underpins the advancement of tissue engineering. Traditional scaffolds based on biodegradable polymers such as poly(lactic acid) and poly(lactic acid-co-glycolic acid) are weak and non-osteoconductive. For bone tissue engineering, polymer-based composite scaffolds containing bioceramics such as hydroxyapatite can be produced and used. The bioceramics can be either incorporated in the scaffolds as a dispersed secondary phase or … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 2 · 30 Jun 2006 · 7,355 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleInduced Microcracking Affects Osteoblast Attachment on Hydroxyapatite Scaffolds for Tissue EngineeringIan O. Smith, Melissa J. Baumann, Eldon D. CaseBone microdamage caused by routine activity plays an important role in triggering targeted and nontargeted bone remodeling. Targeted remodeling occurs near localized areas of microdamage[1-4]. We hypothesize that bone remodeling may be directly and positively influenced by inducing microcracks in hydroxyapatite (HA) scaffolds for bone tissue engineering. A study by Case et al. showed microcracking in HA discs having >98% … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 3 · 30 Sep 2006 · 6,557 accessesView PDFCite
Research ArticleOpen accessIn the keywords3D Printing of Porous Scaffolds for Medical ApplicationsAblah Aljohani, Salil DesaiCustom engineered scaffolds that mimic the physiology of native tissue is an emerging need for successful regenerative medicine. One of the key challenges in current manufacturing methods is the lack of controlled porosity throughout the scaffold structure. In this research, our group explores the fabrication of tissue engineering scaffolds using 3D printing technology. The fused deposition modeling method was utilized … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 3 · 19 Jun 2018 · 8,508 accessesView PDFCite
Research ArticleOpen accessIn the keywordsDevelopment of Cell-Responsive Nanophase Hydroxyapatite for Tissue EngineeringR. Murugan, S. RamakrishnaScaffold plays a critical role in engineering bone tissues by providing necessary structural support for the cells to accommodate and guiding their growth in the three dimensional (3D) space. Therefore, designing scaffold that mimic composition and structural aspects of the bone is of great importance to promote cell adhesion, cell-matrix interactions, osteointegration, tissue formation and continued function. Nanophase hydroxyapatite (HA) … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 3 · 30 Sep 2007 · 7,163 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Study of Morphological Structure, Phase Structure and Molecular Structure of Collagen-PEO 600K Blends for Tissue Engineering ApplicationN. F. Mohd Nasir, M. G. Raha, N. A. Kadri et al.A new material which is collagen/ poly (ethylene oxide) (PEO) blend was developed to determine its possibility as a promising material for tissue scaffold. PEO with average molecular weight of 600,000 and collagen originated from calf skin were dispersed in 0.1 M acetic acid to prepare a concentration of 1 wt% for PEO and 0.15 wt% for collagen. The collagen-PEO600K … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 4 · 31 Dec 2006 · 7,422 accessesView PDFCite
Research ArticleOpen accessIn the keywordsBioceramics for Tissue Engineering Applications-A ReviewSunho Oh, Namsik Oh, Mark Appleford, Joo L. OngThree dimensional (3-D) scaffolds have been explored in an attempt to persuade the body to heal or repair tissues that do not do so spontaneously. Considerable advances in tissue engineering and regeneration have been accomplished over the last decade. However, the material and 3-D scaffolds ideal for optimal regeneration of missing or lost tissues has not been identified. While current … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 2 · 30 Jun 2006 · 10,420 accessesView PDFCite
Review ArticleOpen accessIn the keywordsPresents some Biologically Structured MaterialsRelly Victoria Virgil Petrescu, Raffaella Aversa, Antonio Apicella, Florian Ion Tiberiu PetrescuIn this paper bio-tissue, mathematical modeling serves as a central repository to interface design, simulation and tissue fabrication. Finite element computer analyses will be used to study the role of local tissue mechanics on endochondral ossification patterns, skeletal morphology and mandible thickness distributions using single and multi-phase continuum material representations of clinical cases of patients implanted with the traditional protocols. … …OnLine Journal of Biological Sciences, Vol. 20, Issue 1 · 28 Jan 2020 · 7,046 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Optimization of a Porous Ti6Al4V Bone Construct Using Additive ManufacturingJeffrey Wilk, Glenn Sanders, Shelby Marks et al.Patient specific implants are becoming viable treatment options in some orthopaedic applications through advances in additive manufacturing and 3D printing techniques. One potential application is for treatment of segmental bone defects, particularly in patients suffering from bone cancer. Current treatment options are: Amputation, megaprosthesis, or allografts. These treatments are often highly invasive, may require a partial/full joint replacement and are … …American Journal of Engineering and Applied Sciences, Vol. 10, Issue 1 · 2 Jan 2017 · 7,811 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPhysiologic Human Fluids and Swelling Behavior of Hydrophilic Biocompatible Hybrid Ceramo-Polymeric MaterialsAversa Raffaella, Relly Victoria V. Petrescu, Apicella Antonio, Florian Ion T. PetrescuAll synthetic and natural materials to be used in biomedical applications that involve the contact with human body need to be investigated for their physical and chemical modification induced by the human physiological fluids contact and sorption. The development and testing in human physiological equivalent fluids of new hybrid biomaterials are presented. The role of water and its equilibrium modification … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 4 · 8 Nov 2016 · 8,387 accessesView PDFCite
Research ArticleOpen accessIn the abstractNano-Diamond Hybrid Materials for Structural Biomedical ApplicationRaffaella Aversa, Relly Victoria V. Petrescu, Antonio Apicella, Florian Ion T. PetrescuThe development of new diamond based bio-mechanically active hybrid nano-structured scaffolds for cartilage cells tissue engineering are proposed in this study. Innovative tissue engineering biomimetic materials based on hydrogel have shown attractive physical, biological and mechanical properties in several biomedical applications. A highly biocompatible novel hybrid material based on nanodiamonds and hydrophilic poly-(hydroxyl-ethyl-methacrylate) (pHEMA) is proposed. The aim of this … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 1 · 9 Mar 2017 · 9,183 accessesView PDFCite