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13 articles for “stroma”

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Research ArticleOpen accessEvery word in the titleClozapine and its Major Stable Metabolites, N-desmethylclozapine and Clozapine N-oxide do not Affect Human Bone Marrow Stromal Cells in vitroAvril Pereira, Brian DeanTreatment of refractory schizophrenia with the atypical antipsychotic drug clozapine is associated with life-threatening agranulocytosis, characterised by a drop in neutrophil count. Theoretically, toxicity may be accounted for by direct action of parent drug or one of its stable metabolites on bone marrow stroma given importance of these cells to neutrophil maturation. Effects of clozapine, N-desmethylclozapine and clozapine N-oxide on … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 1 · 31 Mar 2006 · 7,109 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleAbout the Cyanobacteria and StromatolitesFlorian Ion Tiberiu Petrescu, Liviu Marian UngureanuStromatolites are layered biochemical accretionary structures formed in shallow water by the trapping, binding and cementation of sedimentary grains in biofilms (specifically microbial mats), especially cyanobacteria. Stromatolites occur widely in the fossil record of the Precambrian but are rare today. Life on Earth was born at least 3.7 billion years ago, but since then the number of living things has … …OnLine Journal of Biological Sciences, Vol. 22, Issue 1 · 17 Feb 2022 · 8,230 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleImatinib Mesylate Inhibits Glucose Uptake in Gastrointestinal Stromal Tumor Cells by Downregulation of the Glucose Transporters Recruitment to the Plasma MembraneHans Prenen, Cristiana Stefan, Bart Landuyt et al.Imatinib mesylate, the inhibitor of the KIT protein tyrosine kinase that is constitutively activated in Gastrointestinal Stromal Tumors (GISTs), has been established as the first highly effective drug in the treatment of patients with advanced GISTs. Recent studies suggest that changes in the glucose metabolism could be an additional mechanism of the anti-proliferative action of imatinib. The aim of this … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 2 · 30 Jun 2005 · 7,245 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAn Integrated Framework to Predict the Strength of New SMILE Using Graph Attention NetworkSandhi Kranthi Reddy, S. V. G. ReddyMachine Learning (ML) and Deep Learning (DL) have significantly advanced various fields, including healthcare, finance, autonomous systems, and scientific research. In healthcare, these technologies have been widely applied to disease prediction, such as cancer and diabetes. However, the challenge of drug resistance persists, creating a need for more effective drugs. Developing new drugs is a complex, expensive, and time-intensive process, … …Journal of Computer Science, Vol. 21, Issue 10 · 25 Nov 2025 · 2,157 accessesView PDFCite
Research ArticleOpen accessIn the abstractPathological and Immunohistochemical Findings of Prostate Glands from Clinically Normal DogsFiras Mohammed Abed, Asseel Mohammed Rahawi, Hadil Basim Al-Sabaawy et al.To investigate the incidental histopathologic findings in clinically normal dogs and determine the immunohistochemical expression of several tissue-specific differentiation markers. The University of Mosul's animal research ethical committee authorized this study (UoM.Dent/A.DM.L.1/22). Seven samples were obtained from the veterinary hospital in cooperation with the College of Dentistry. Dogs with two detectable testicles were considered intact. Dogs with a history of … …American Journal of Animal and Veterinary Sciences, Vol. 18, Issue 4 · 13 Nov 2023 · 5,198 accessesView PDFCite
Research ArticleOpen accessIn the abstractCOMPUTER-AIDED DECISION SYSTEM FOR REFRACTIVE SURGERIES WITH EXCIMER LASERRawan Baroudy, Bassam Lala124 patients (248 eyes) who intended to refractive surgery by Excimer laser were studied to implement our goal of this study which is design and operate a computer-aided decision system for optimal choosing the best refractive surgery based on patient needs, Starting from corneal topography and aberration images, using RGB and HSI color spaces and decision tree. The system also … …Journal of Computer Science, Vol. 10, Issue 2 · 13 Nov 2013 · 6,651 accessesView PDFCite
Research ArticleOpen accessIn the abstractHistology and Histomorphology of Hormone Treated Surati Buffalo Udder TissueH. H. Mehta, A. K. Patel, K. N. Nandasana et al.In the global dairy scenario, India has the distinction of being the largest milk producing nation of the total milk production of 100.9 million tons in 2006-2007, about 55.6% has been contributed by buffalo. Buffalo is a more efficient milk producer than an indigenous cow. The present study was carried out to study the morphological changes associated with induced lactation … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 2 · 15 Apr 2013 · 7,199 accessesView PDFCite
Research ArticleOpen accessIn the abstractMicroanatomy and Histochemistry of the Salt Glands of the Kentish Plover, Charadrius alexandrines (Aves, Charadriidae)Bashir M. JarrarProblem statement: Histological and histochemical investigations on the salt glands of birds are very limited. The present study was performed to characterize the microanatomy and histochemistry of the salt glands of the Kentish plover (Charadrius alexandrines). Approach: Salt glands of the bird under study were fixed, dehydrated, cleared, impregnated and blocked out by paraffin wax. Paraffin sections were utilized in … …OnLine Journal of Biological Sciences, Vol. 9, Issue 3 · 30 Sep 2009 · 6,923 accessesView PDFCite
Research ArticleOpen accessIn the abstractInfluence of Sturgeon Protein Fractions on Active Peptide Generation via Enzymatic HydrolysisMengjie Lu, Yingmei Hou, Yejing Sun et al.To identify the sturgeon protein component responsible for generating bioactive peptides, including antioxidant peptides and alcohol dehydrogenase (ADH) promoting peptides, sturgeon protein and its isolated protein components (sarcoplasmic, myofibrillar, and stromal proteins) were studied. Among the four isolated protein components, stromal protein demonstrated the highest susceptibility to enzymatic hydrolysis (P<0.05). Besides, pepsin and alkaline protease are the most effective enzymes … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 1 · 8 Apr 2026 · 1,419 accessesView PDFCite
Research ArticleOpen accessIn the abstractMorphology and Histochemistry of the Corpus Luteum (CL) of Ovaries of Pregnant and Infertile CowsEvgeny Skovorodin, Svetlana Bogolyuk, George Bazekin et al.The purpose of our study is to study the functional morphology of the Corpus Luteum (CL) of the ovaries of pregnant and infertile cows in normal and pathological conditions. For that purpose, the ovaries of cows were examined after slaughter, histological and histochemical examination of the CL was carried out. For the antemortem examination of the ovary, the biopsy method … …American Journal of Animal and Veterinary Sciences, Vol. 15, Issue 4 · 23 Oct 2020 · 6,610 accessesView PDFCite