6 articles for “skin disorders”

Research ArticleOpen accessIn the keywordsDietary Beta-1,3/1,6-Glucans Reduce Clinical Signs of Canine AtopyA. C. Beynen, D. H.J. Saris, P. M. Paap et al.Problem statement: There was evidence that beta-1,3/1,6-glucans modulate inflammatory activity. In an open, non-controlled trial, purified beta-1,3/1,6-glucans were found to improve the clinical signs of dogs with undefined chronic skin disorders. Given the design of that study, further work was required on the efficacy of beta-1,3/1,6-glucans in the treatment of canine atopy. Approach: The influence of a purified preparation of … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 9 Jan 2012 · 9,979 accessesView PDF Cite

Research ArticleOpen accessIn the abstractExploring the Relationship Between Skin Barrier Function, Sensitivity, and Repair MechanismsXiaoqing Yan, Yusong Shi, Jiguang YangFor healthy skin, the skin's barrier function must remain maintained. Many different molecular while immunological signaling mechanisms are involved in skin barrier control. The control of a healthy skin barrier, particularly acid mantle maintenance and proper amounts of ceramides, may help dermatologists develop remedies for skin barrier disruption disorders. In contrast, new medicines could focus on signaling pathways to offer … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,893 accessesView PDF Cite

EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,862 accessesView PDF Cite

Research ArticleOpen accessIn the abstractDevelopment of a Short-Term Canine Full-Thickness Skin Organ Culture Method under Serum-Free ConditionsFrancesca Abramo, Andrea Pirone, Carla Lenzi et al.Full-thickness canine skin organ culture models could provide an entirely new opportunity for studying wound healing, keratinization disorders and allergic skin diseases, all of which have high prevalence and severe impact on canine quality of life. Here we present a canine organ culture method for the short-term maintenance of full-thickness, adult, canine skin in serum-free medium and investigate the possibility … …American Journal of Animal and Veterinary Sciences, Vol. 11, Issue 2 · 13 Jun 2016 · 7,380 accessesView PDF Cite

Review ArticleOpen accessIn the abstractThe Duality of AIM2 Inflammasome: A Focus on its Role in Autoimmunity and Skin DiseasesMiriam CanaveseUnderstanding the inflammasome biology is one of the most exciting challenges in immuno-pharmacology. The role of the inflammasomes has been recognized in the host defense mechanism against invading pathogens and in the development of several conditions, such as cancer, auto-inflammatory, autoimmune, metabolic and neurodegenerative disorders. DNA recognition by the cells is a crucial immunological step leading to the initiation of … …American Journal of Pharmacology and Toxicology, Vol. 11, Issue 1 · 23 Apr 2016 · 7,369 accessesView PDF Cite

Technical ReportOpen accessAll words, across the recordInfluences of Tactile Sensation on Pinch Force under Loaded and Unloaded ConditionsPoh Kiat Ng, Kian Siong Jee, Adi Saptari, Chiew Yean NgAlthough researchers have studied various parameters that affect grip force, few studies investigate the effects of tactile sensation on pinch force. This study aims to determine the influences of tactile sensation on pinch force with a special emphasis on screw knobs under loaded and unloaded conditions. The participants included 32 manual workers who were required to pinch and turn the … …American Journal of Applied Sciences, Vol. 12, Issue 8 · 17 Sep 2015 · 6,904 accessesView PDF Cite