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15 articles for “protein biomarker”
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Research ArticleOpen accessIn the keywordsCloning and Expression of SCAMP3 in Transgenic Silkworm (Bombyx mori)Selly S. Rajagukguk, Sabar Pambudi, Astari Dwiranti et al.SCAMP3 (Secretory Carrier Membrane Protein 3) is a crucial component of vesicular trafficking pathways and plays important roles in endocytosis and protein recycling. Previous studies demonstrate SCAMP3 dysregulation in various cancers, suggesting potential applications as a biomarker and therapeutic target. Understanding SCAMP3 expression and post-translational processing provides insights into its biological functions and potential applications in cancer diagnostics and therapy. … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 16 Feb 2026 · 1,521 accessesView PDFCite
Research ArticleOpen accessIn the keywordsA Proteomics Analysis of Drought Stress-Responsive Proteins as Biomarker for Drought-Tolerant Sugarcane CultivarsNisachon Jangpromma, Supansa Kitthaisong, Khomsorn Lomthaisong et al.Problem statement: The prime objective in breeding selection process of drought-tolerant sugarcane is to identify the correlating marker, which could lead to rapid screening for drought-tolerant cultivars. In this study, we have reported an unknown 18-kDa protein (p18) along with other stress-inducible proteins to be highly expressed in sugarcane leaves under drought stress condition. Approach: The 2D-PAGE patterns of proteins … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 2 · 30 Jun 2010 · 9,814 accessesView PDFCite
Research ArticleOpen accessIn the abstractsuPAR as an Inflammatory and Preclinical Atherosclerotic Marker in Hypovitaminosis DShravan Ajith Panchwadkar, Sudha Kuthethur, Neelam Manjunath Pawar et al.The mechanistic link between inflammation and atherosclerosis highlights the critical role of immune modulation in cardiovascular disease. The soluble urokinase plasminogen activator receptor (suPAR), an immune-derived factor, has recently emerged as a non-specific inflammatory marker across chronic diseases and infections. All cells within the atherosclerotic arterial wall can express uPAR and release urokinase, which plays a key role in the … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 30 Mar 2026 · 1,122 accessesView PDFCite
Research ArticleOpen accessIn the abstractDiagnostic Potential of Inflammatory Biomarker Levels in the Serum of Patients with Hepatitis B Infection: A Retrospective StudyHyeokjun Yun, Bo Kyeung Jung, In Soo Rheem et al.This study aimed to evaluate the diagnostic biomarker potential of C-Reactive Protein (CRP) and Procalcitonin (PCT) levels in the serum of individuals infected with the Hepatitis B Virus (HBV). The patients were divided into two age groups: Younger (<60 years) and older (≥60 years). An Electrochemiluminescence Immunoassay (ECLIA) platform was employed for the serological analysis to quantify the biomarker levels. … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 3 · 10 Aug 2023 · 5,270 accessesView PDFCite
Research ArticleOpen accessIn the abstractDrug-Protein Interactions for Clinical Research by Nucleic Acid Programmable Protein Arrays-Quartz Crystal Microbalance with Dissipation Factor Monitoring Nanoconductometric AssayClaudio Nicolini, Rosanna Spera, Nicola Luigi Bragazzi, Eugenia PechkovaConductometric monitoring of drug-gene and drug-protein interactions is of fundamental importance in the field of molecular pharmacology. Here, we present our main findings and characterizations of an important antiblastic used in neuro-oncology (Temozolomide), interacting with selected proteins that represent predictive biomarkers of the rate survival of the patients, of the outcome of chemotherapy and resistance to drug itself (namely, BRIP1 … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 3 · 17 Nov 2014 · 8,506 accessesView PDFCite
Research ArticleOpen accessIn the abstractC-Reactive Protein and Serum Procalcitonin Levels as Markers of Bacterial Upper Respiratory Tract InfectionsDiamantis P. Kofteridis, George Samonis, Alexander D. Karatzanis et al.Problem statement: Upper Respiratory Tract Infections (URTIs) are the most frequent of the community with major social and financial impact. Hence, early and proper diagnosis is of utmost importance. Biomarkers such as the circulating levels of Procalcitonin (PCT) have been shown to be elevated in systemic bacterial infections, but remain relatively low in viral infections and inflammatory diseases and have … …American Journal of Infectious Diseases, Vol. 5, Issue 4 · 31 Dec 2009 · 7,135 accessesView PDFCite
Research ArticleOpen accessIn the abstractCorrelation of Some Biochemical Parameters between Serum and Saliva of Patients with Breast CancerOmar Atrooz, Huthaifa TarawnehRegular breast cancer laboratory examination of serum is aburden on patients, therefore understanding salivary test methods' featuresand limits is important for diagnosis. The study aims to evaluate thebiochemical parameters in the serum and saliva of breast cancer and controlindividuals. Furthermore, to investigate the correlation between two biofluidlevels in both groups. This cross-sectional study recruited Jordanian femalesincluding 40 breast cancer patients … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 20 May 2025 · 4,487 accessesView PDFCite
Research ArticleOpen accessIn the abstractAcute Phase Proteins, Lipid Profile and Proinflammatory Cytokines in Healthy and Bronchopneumonic Water Buffalo CalvesSabry M. El-Bahr, Wael M. EL-DeebThe aim of the present study was to evaluate the diagnostic value of Acute Phase Proteins (APP), lipid profiles and proinflammatory cytokines in healthy and bronchopneumonic water buffalo calves. Therefore, sixty water buffalo calves (9±1 month old, 175±15 kg) were divided into two equal groups, the first group represented healthy, control, calves whereas calves of the second group were affected … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 1 · 18 Mar 2013 · 8,415 accessesView PDFCite
Research ArticleOpen accessIn the abstractLemon Pepper Fruit Extract (Zanthoxylum acanthopodium DC.) Suppresses the Expression of Inflammatory Mediators in Lipopolysaccharide-Induced Macrophages In VitroYanti, Theodorus Eko Pramudito, Nerissa Nuriasari, Katarina JulianaProblem statement: Lemon pepper fruits (Zanthoxylum acanthopodium DC.; Rutaceae) have been used as a traditional source against stomach ache by Batak people in North Sumatera province, Indonesia. However, its scientific evidence for treatment of inflammatory disorders particularly gastritis has not been reported. Approach: Here, we investigated the inhibitory effects of Lemon Pepper Fruit Extract (LPFE) against inflammatory biomarkers by conducting … …American Journal of Biochemistry and Biotechnology, Vol. 7, Issue 4 · 14 Feb 2012 · 9,581 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Novel Rodent Model of Autism: Intraventricular Infusions of Propionic Acid Increase Locomotor Activity and Induce Neuroinflammation and Oxidative Stress in Discrete Regions of Adult Rat BrainDerrick F. MacFabe, Karina Rodríguez-Capote, Jennifer E. Hoffman et al.Innate neuroinflammatory changes, increased oxidative stress and disorders of glutathione metabolism may be involved in the pathophysiology of autism spectrum disorders (ASD). Propionic acid (PPA) is a dietary and gut bacterial short chain fatty acid which can produce brain and behavioral changes reminiscent of ASD following intraventricular infusion in rats. Adult Long-Evans rats were given intraventricular infusions of either PPA … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 12,613 accessesView PDFCite