3 articles for “mycobacterial smegmatis”

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Research ArticleOpen accessIn the keywordsMycobacterium Smegmatis Infection of a Lumbar Spine Instrumented FusionFrank Allen ZimbaProblem statement: To demonstrate the presentation of atypical mycobacterial postsurgical infections and their management. Approach: Single patient case report. Results: Successful management of atypical mycobacterial post operative infection with preservation of instrumented hardware posterior pedicle screw fixation and interbody cages. Conclusion: This report suggests that these atypical mycobacterial infections can be eradicated with successful outcomes with preservation of spinal instrumentation. …American Journal of Infectious Diseases, Vol. 7, Issue 1 · 27 Jun 2011 · 8,802 accessesView PDF Cite

Research ArticleOpen accessIn the abstractA SHORT INTERFERING RNA MOLECULAR BEACON FOR THE ATTENUATION OF MYCOBACTERIAL INFECTIONRemo George, Kathy Nugent, Norman Bolus et al.The ability of the pathogen Mycobacterium Tuberculosis (MTB) to invade and survive within macrophages of granulomas is attributed to the product of the Mammalian Cell Entry (MCE) operon whose gene, mce4A, encodes a cholesterol transporter that transports host lipids into the bacterium that allows the bacterium to survive during chronic infection. Here, we proposed and tested the hypothesis that a … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 1 · 4 Mar 2014 · 7,774 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAn Inducible System for the Identification of Target Genes for a Regulator in MycobacteriaShruti Jain, Garima Khare, Pushplata Tripathi, Anil K. TyagiWe described principle and application of an inducible system for identification of target genes of a given mycobacterial protein with a regulatory function. This vector system, a promoterprobe vector, carries (i) promoterless lacZ as the reporter gene and (ii) the mycobacterial gene encoding the regulatory protein under the transcriptional control of the promoter of highly inducible mycobacterial gene encoding acetamidase. … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 3 · 30 Sep 2008 · 7,249 accessesView PDF Cite