3 articles for “mitochondrial fraction”

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Research ArticleOpen accessIn the keywordsProtective Effect of Enicostemma littorale Blume Methanolic Extract on Gentamicin-Induced Nephrotoxicity in RatsNiraj Mukundray Bhatt, Kinjal Chauhan, Sharad Gupta et al.Problem statement: The Amino glycoside antibiotics cause drug induced nephrotoxicity at therapeutic doses and thus limits the use clinically. Oxidative stress is one of the main reasons for the development of nephrotoxicity. Approach: In light of this the aim of the present study was to investigate the role of mitochondrial as well as post-mitochondrial oxidative stress in the development of … …American Journal of Infectious Diseases, Vol. 7, Issue 4 · 30 Nov 2011 · 9,547 accessesView PDF Cite

Research ArticleOpen accessIn the abstractInvolvement of Microsomal Na+/K+ ATPase Activity in the Mechanism of Action of Dopaminergic D2 ReceptorsAbdulrahim Abu-JayyabProblem statement: Our previous research has shown that mitochondrial ATPase may have a role in the action of dopaminergic D2 receptors. It is therefore, thought of interest to investigate the effect of bromocriptine, sulpiride or their combination on the mitochondrial and microsomal ouabain sensitive and ouabain insensitive Na+/K+-ATPase in the liver of rats. Approach: In vivo treatment was carried out … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 6,971 accessesView PDF Cite

Research ArticleOpen accessAll words, across the recordComparative Physiological and Molecular Study of Some Sheep Breeds in Saudi ArabiaMohammad S. AL-Harbi, Hamed S. Alwagdany, Sayed A.M. AmerNaemi, Heri, Najdi and Sawakni sheep breeds inhabiting Kingdom of Saudi Arabia were studied on both physiological and molecular bases. Native polyacrylamide gel-electrophoreses for two enzymes Malate Dehydrogenase (Mdh) and Malic Enzyme (Me) recorded 5 isoenzyme loci from which 4 were polymorphic and 1 was monomorphic. Mdh showed three fractions, the first was recorded in Sawakni and Najdi breeds, the … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 2 · 20 Jun 2013 · 8,388 accessesView PDF Cite