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24 articles for “miR-31”

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Research ArticleOpen accessPhrase in the titleThe Construction of Two and Three Dimensional Molecular Models for the miR-31 and Its Silencer as the Triple Negative Breast Cancer BiomarkersArli Aditya ParikesitThe Triple Negative Breast Cancer (TNBC) is considered as the most difficult Breast Cancer type to be medicated. So far, the acceptable medication and diagnostics measure are based upon the proteomics-world view, especially with utilizing the natural products and their derivatives as drug candidates. However, as the transcriptomics-studies are getting more advanced, the research on non-coding (nc)RNA is being considered … …OnLine Journal of Biological Sciences, Vol. 18, Issue 4 · 18 Oct 2018 · 7,772 accessesView PDFCite
Research NotesOpen accessEvery word in the titleNuciferine Attenuates Cigarette Smoke-Induced Senescence in HepG-2 Cells via the miR-217/SIRT1/Nrf2 PathwayYun-Hong Zhao, Yi-Meng Ge, Wei-Jia Xu et al.The lotus leaf, widely used in both medicine and cuisine, contains bioactive compounds with therapeutic potential. Nuciferine (NF), an active constituent of significant importance, is extracted from the lotus leaf. The present study sought to uncover the molecular pathways through which Nuciferine (NF) mitigates cellular senescence triggered by Cigarette Smoke Components (CSCs) in HepG-2 cells, employing an experimental model where … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 4 Oct 2025 · 2,296 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleExpression of Exosome-Derived MicroRNAs miR-21 and miR-135 are Differentially Regulated Among Dental Pulp Stem CellsMatthew Hunsaker, Brandon Richards, Adelle Fuller et al.Dental Pulp Stem Cells (DPSCs) are a type of mesenchymal stem cell that has the potential to differentiate into various types of cells and tissue. Previous research has demonstrated that DPSCs can be easily accessed and isolated from both permanent and deciduous teeth, such as wisdom teeth or third molars, although there is less information available about the mechanisms and … …Current Research in Medicine, Vol. 11, Issue 1 · 10 Jan 2023 · 10,533 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEvaluation of Mir 29c-3p and Mir 31-5p Serum Values in Predicting Nephropathy in Type 2 Diabetic PatientsMona S. Habieb, Nesreen Gamal Elhelbawy, Khaled M. Elzorkany et al.Diabetic Nephropathy (DN) is a prime complication of diabetes with various pathological mechanisms. microRNAs (miRNAs) have emerged as an important factor in the pathogenesis of renal disorders. We aimed to analyze serum miR 29c-3p and miR 31-5p in diabetic patients in relation to albuminuria and eGFR. Also, the correlations between these miRNAs and cystatin C were assessed. This study was … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 1 · 17 Feb 2022 · 6,449 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleExpression of microRNA miR-27, miR-124 and miR-218 Among Dental Pulp Stem Cell (DPSC) IsolatesMark Whiting, Karl KingsleyDental Pulp Stem Cells (DPSCs) are non-embryonic, mesenchymal stem cells that may have significant potential for therapeutic and regenerative biomedical applications. MicroRNAs are small non-coding RNA molecules that can act as transcriptional activators and repressors in many types of mesenchymal stem cells. To date, few studies have evaluated the expression or activity of microRNAs among dental pulp stem cells. Using … …Current Research in Dentistry, Vol. 9, Issue 1 · 1 Jan 2019 · 8,167 accessesView PDFCite
Research ArticleOpen accessIn the keywordsRadiation Triggered Phenotypic Changes of Regulatory T CellsLantao Liu, Yan Peng, Deqin Zhang, Dongsheng NiuIonizing radiation disrupts the immune balance easily. Regulatory T (Treg) cells directly affect the immune balance after radiation exposure. Meanwhile, the present study is to investigate the survival ability and phenotypic changes of Treg cells induced by 60Co γ-rays in order to expand the understanding on how Treg cells modulated by radiation. Mice lymphocytes were isolated from thymus and spleen … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 1 · 20 Mar 2022 · 5,828 accessesView PDFCite
Research ArticleOpen accessIn the keywordsHow Micrornas Affect the Expression of Human Leukocyte Antigeng in PregnancyAyla Carmel Kempers, Marie Van Dijk, Cees OudejansThe expression of Human Leukocyte Antigen G (HLA-G) on Fetal Extravillous Trophoblast (EVT) cells during pregnancy plays an important role in preventing the fetus from rejection by suppressing the maternal immune system. Decreased expression levels of HLA-G have already shown to be associated with several complications of pregnancy such as pre-eclampsia. However, it remains largely unknown how HLA-G gene expression … …American Journal of Immunology, Vol. 8, Issue 4 · 18 Oct 2012 · 7,124 accessesView PDFCite
Research ArticleOpen accessIn the keywordsFPGA-Based Architecture for a Generalized Parallel 2-D MRI Filtering AlgorithmSami Hasan, Said Boussakta, Alex YakovlevProblem statement: Current Neuroimaging developments, in biological research and diagnostics, demand an edge-defined and noise-free MRI scans. Thus, this study presents a generalized parallel 2-D MRI filtering algorithm with their FPGA-based implementation in a single unified architecture. The parallel 2-D MRI filtering algorithms are Edge, Sobel X, Sobel Y, Sobel X-Y, Blur, Smooth, Sharpen, Gaussian and Beta (HYB). Then, the … …American Journal of Engineering and Applied Sciences, Vol. 4, Issue 4 · 20 Feb 2012 · 8,021 accessesView PDFCite
Research ArticleOpen accessIn the author namesEffect of Seaweed Extracts on Rice Growth and Tolerance to Salinity, Drought and Blast (Magnaporthe oryzae)Mir Sayeada Alam, Jannatun Nayeema, S. M. Rafiquzzaman, Motaher HossainRice, a primary staple, confronts a multitude of biotic and abiotic stresses. Drought and salinity, exacerbated by climate change and blast disease caused by Magnaporthe oryzae, significantly contribute to yield losses. To tackle the problems, two types of seaweeds-one known as Hypnea musciformis and another unknown-were collected from Saint Martin, Cox's Bazar, Bangladesh and then examined for the potential of … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 31 May 2024 · 6,506 accessesView PDFCite
Case ReportOpen accessIn the author namesActinomyces Odontolyticus with Klebsiella and Bacteroides Presenting as Facio-Cervical Abscess with Extension to Scalp and no Sinus TractTanveer Mir, Anita Choudhary, Anshu Wadehra et al.Actinomycosis is a rare infectious bacterial disease caused by various Actinomyces species. Being very rare, Actinomyces is easily misdiagnosed. Actinomyces are common commensals of the oral cavity which predispose to local infections. We report a case of a 67-year-old female who initially presented with swelling of the left sided face which later on proved to be a mixed infection with … …American Journal of Infectious Diseases, Vol. 15, Issue 2 · 14 Jun 2019 · 7,241 accessesView PDFCite