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31 articles for “liver enzymes”
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Research ArticleOpen accessEvery word in the titleChange in Growth Performance and Liver Function Enzymes of Broiler Chickens Challenged with Infectious Bursal Disease Virus to Dietary Supplementation of Methionine and ThreonineElham Maroufyan, Azhar Kasim, Seyed Reza Hashemi et al.Problem statement: The aim of this study was to verify the effects of methionine and threonine supplementations higher than the NRC recommendation on growth performance, liver function enzymes, blood parameters and immune tissues of broiler chickens challenged with infectious bursal disease. Approach: A total of 450 day-old male broiler chicks were assigned to nine groups. Chickens were fed by three … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 1 · 31 Mar 2010 · 9,469 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAroclor 1254 Toxicity to Mice Liver Membrane AtpasesShweta Pathak, Rahul KunduPresent communication reports the sub-acute dose and exposure duration dependent effects of Aroclor 1254 on total, Na+, K+, Ca++ and Mg++-ATPases of the mouse liver cells. The study tests two hypotheses, (a) whether the sublethal dose or the exposure duration dependent in vivo exposure of hydrophobic PCB (Aroclor 1254) affects the hydrophilic membrane-bound ion dependent ATPases of the liver cells … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 2 · 13 Jul 2013 · 6,791 accessesView PDFCite
Research ArticleOpen accessIn the keywordsOccupational Exposure of Pesticides on Activities of Alanine aminotransferase and γ-Glutamyltranspeptidase in Blood among Vegetables FarmersShamsul Bahari Shamsudin, T. Hang YapProblem statement: Most vegetable farmers are using agricultural chemicals on their farms. Many of these chemicals are used to control pests and are known as pesticides. Pesticides can be considered according to their chemical basis. Most of the more toxic pesticides fall into chemical groups of organophosphates, carbamates and bipyridyls. Approach: The general objective to study the level of liver … …Current Research in Medicine, Vol. 2, Issue 2 · 4 Oct 2011 · 7,938 accessesView PDFCite
Case ReportOpen accessIn the abstractSurvival Following Severe Paraquat Poisoning a Case Study from the Andaman and Nicobar IslandsShiv Shankar Singh, Colin Sanchez, Prasan Kumar PandaParaquat poisoning continues to pose a significant public health challenge in the Andaman and Nicobar Islands, largely due to its alarmingly high mortality rate. In this report, we present the case of a 39-year-old male farmer who ingested 30 mL of paraquat with the intent of suicide. Initially, the patient underwent prompt gastric lavage and exhibited relative stability. Upon admission, … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 22 Jan 2025 · 10,605 accessesView PDFCite
Research ArticleOpen accessIn the abstractTrilobatin Possesses Protective Potentials on H2O2-Induced HepG2 Cells by Suppressing Oxidative Stress: Involvement of Nrf2/Keap1 Signal PathwayYuhan Zhai, Yuqing Zhang, Yaping Li et al.Trilobatin, a natural dihydrochalcone compound, possesses various biological activities. However, few investigations have been carried out on the mechanisms of trilobatin against oxidative stress. To comprehend the effects and mechanism of trilobatin on oxidative stress after hepatic injury, H2O2-induced HepG2 cells were used in this research. The results indicated that trilobatin enhanced the viability and improved the apoptosis morphology of … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 22 Dec 2023 · 5,087 accessesView PDFCite
Research ArticleOpen accessIn the abstractIsoquinoline Alkaloids and the Ionophore Monensin Supplemented Alone or Combined on Ruminal Fermentation and Nutrient Digestibility in Steers Fed a High-Energy DietJesús D. Urías-Estrada, Beatriz I. Castro-Pérez, Alfredo Estrada-Angulo et al.The aim of this experiment was to investigate the Influence of Alkaloids (IQA) and sodium Monensin (MON) supplementation on characteristics of ruminal fermentation, microbial protein synthesis and site and extend of digestion. For this, 4 cannulated steers were used in a 4×4 Latin square design. Treatments consisted of a high-energy basal diet supplemented with: (1) No additive (Control), (2) 15 … …American Journal of Animal and Veterinary Sciences, Vol. 16, Issue 3 · 7 Oct 2021 · 6,580 accessesView PDFCite
Research ArticleOpen accessIn the abstractModeling Hepatocellular Toxicity of Enavatuzumab, a Humanized Anti-TweakR AntibodyDonghee Choi, Yanhong Zhu, Debra Tien Chao et al.In a Phase 1 clinical study, treatment with enavatuzumab, a humanized monoclonal antibody to TweakR, resulted in liver toxicity in a subset of patients. The objective of this current study was to evaluate the ability of preclinical studies to predict liver toxicity in humans. Enavatuzumab was evaluated in cynomolgus monkeys, where serum liver enzyme and cytokine levels were measured and … …American Journal of Pharmacology and Toxicology, Vol. 12, Issue 2 · 9 Nov 2017 · 7,719 accessesView PDFCite
Research ArticleOpen accessIn the abstractAmeliorative Impacts of Tribulus terrestris Against Ivermectin-Induced Hepato-Renal Toxicity in Rabbit: Pharmacological and Histopathological StudySally I. Ismaiel, Sameh M. Farouk, Raafat A. El-Ramady, Waleed F. KhalilThe current work aimed to investigate the protective effects of Tribulus terrestris extracts against ivermectin-induced hepatic and renal toxicity in male rabbit. Selenium plus vitamin E was used as a comparative standard drug to evaluate the efficacy of Tribulus terrestris extract on some hematological parameters, kidney and liver enzymes as well as associated histopathological changes. This work was carried out … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 1 · 12 Jan 2017 · 7,766 accessesView PDFCite
Research ArticleOpen accessIn the abstractEFFECT OF PIOGLITAZONE ON HEPATIC ULTRA-STRUCTURE AND METABOLIC CHANGES INDUCED BY A HIGH SUCROSE DIET IN RATSMohamed D. Morsy, Ahmed S. Khashaba, Ahmed I. Agamy, Refaat A. EidPioglitazone (Pio) is a PPAR-γ agonist insulin sensitizer has anti-inflammatory activity. Our novel aspect was to investigate its hepatic anti-inflammatory activity at the level of ultra-structure and enzymatic changes in a high sucrose diet animal model. Forty male Sprague Dawley rats were divided into four equal groups: Control; control Pio; high sucrose diet; high sucrose diet Pio treated groups. Fourteen … …American Journal of Applied Sciences, Vol. 11, Issue 7 · 23 Apr 2014 · 6,732 accessesView PDFCite
Research ArticleOpen accessIn the abstractEFFECTS STUDY OF NIGELLA SATIVA, ITS OIL AND THEIR COMBINATION WITH VITAMIN E ON OXIDATIVE STRESS IN RATSAmr A. RezqAntioxidants or free radical scavengers are very important in protecting the living cells against any damage induced by free radicals. The effects of Nigella Sativa Extract (NSE), Nigella Sativa Oil (NSO) and Vitamin E (Vit. E) and the combination of NSE or NSO with Vit. E on potassium bromate (KBrO3)-induced oxidative stress in male rats were investigated. Forty nine Sprague … …American Journal of Applied Sciences, Vol. 11, Issue 7 · 23 Apr 2014 · 7,005 accessesView PDFCite