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6 articles for “in vitro permeation”
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Research ArticleOpen accessPhrase in the titleAn in vitro Permeation of Phyllanthus amarus Extract Through Human and Shed Snake SkinsAroonsri Priprem, S. Radapong, S. Preeprame et al.An in vitro permeation of a hydroalcoholic extract of Phyllanthus amarus (PaE) was investigated using excised human epidermis and shed king cobra skin as the barrier membranes. Donor and receptor compartments of diffusion cells were pH-controlled to simulate the permeation environment of the human skin. The PaE was analyzed by using normal-phase densitometric TLC detected at λ 280 nm and … …American Journal of Agricultural and Biological Sciences, Vol. 2, Issue 3 · 30 Sep 2007 · 7,787 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleShed Skin of Ophiophagus hannah: Structural Topography and In Vitro Permeation of Nicotine and PhenolA. Priprem, T. Pongjanyakul, C. Khamlert et al.Scales of the dorsal portions of shed skin of king cobras (Ophiophagus hannah) was used as the barrier membrane for in vitro permeation of nicotine and phenol at toxic or irritable concentration levels. The scales were placed between solutions of nicotine or phenol in a donor solution at pH 5.6 and a receptor solution at pH 7.4. Cumulative amounts of … …American Journal of Animal and Veterinary Sciences, Vol. 2, Issue 4 · 31 Dec 2007 · 6,735 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleComparative Permeation Studies between Scale Region of Shed Snake Skin and Human Skin In vitroAroonsri Priprem, Chidchanok Khamlert, Thaned Pongjanyakul et al.Scales of shed king cobra (Ophiophagus hannah) skin from the dorsal portions, (SSS) and human breast epidermis (HE) were used as barrier membranes for comparison in an in vitro drug permeation study of nine active compounds (MW range 150-300 g mol-1, pKa 3-10). Each compound, saturated in a donor solution at pH 4.0 or 5.6, permeated through the barrier membrane, … …American Journal of Agricultural and Biological Sciences, Vol. 3, Issue 1 · 31 Mar 2008 · 8,413 accessesView PDFCite
Research ArticleOpen accessIn the abstractDevelopment and Optimization of Plant Extract Loaded Nanoemulsion Mixtures for the Treatment of Inflammatory DisorderMukesh Gohel, Tejal Soni, Lal Hingorani et al.In current study, a nanoemulsion as drug delivery system (NE) of spray dried Boswellia Serrata Extract (BSE) was developed and characterized to compare it in vitro/Ex vivo diffusion with reference formulation. Pseudo-ternary phase diagrams were constructed by phase diagram by aqueous titration method, of which the evaluation method was improved for solubility, Droplet size and transmittance. The formulation of BSE-loaded … …Current Research in Drug Discovery, Vol. 1, Issue 2 · 26 Jan 2015 · 14,064 accessesView PDFCite
Research ArticleOpen accessIn the abstractFormulation and Evaluation of a Novel Needle-Free Hepatitis B Surface Antigen Delivery SystemC. D. Licy, K. Premalatha, Annie Shirwaikar, Arun ShirwaikarProblem statement: Hepatitis B is a major public health problem, killing 1-2 million people annually, despite the introduction of an effective vaccine in 1982. Approximately 400 million persons worldwide have chronic hepatitis B. This is due to problems associated with vaccine delivery, stability and cost. Hence the present challenge in Vaccinology is to develop safer, cheaper and easy-to-deliver forms of … …Current Research in Medicine, Vol. 1, Issue 2 · 30 Oct 2010 · 6,819 accessesView PDFCite
Research ArticleOpen accessIn the abstractPreparation and Properties of Copolyanhydrides Based on 2-Hexadecylsuccinic Acid and Sebacic AcidYousef Hamdan, Xiangmei Jiang, Kaixun Huang, Kaichao YuPoly(2-hexadecylsuccinic acid-sebacic acid) (P(HSA-SA)) copolymers have been prepared by melt polycondensation. The copolymers were characterized by FT-IR, 1HNMR, gel permeation chromatography (GPC), differential scanning calorimetry (DSC) and thermal gravimetric analysis (TGA). In vitro studies showed that all our prepared copolymers are degradable in phosphate buffer at 37°C. The release profiles of hydrophilic model drug, ciprofloxcin hydrochloride, from the copolymers, follow … …American Journal of Applied Sciences, Vol. 4, Issue 3 · 31 Mar 2007 · 7,427 accessesView PDFCite