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54 articles for “immunomodulator”
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Research ArticleOpen accessEvery word in the titlePotential of Fig Leaf (Ficus carica L.) as Immunomodulatory Agent in vitro and in SilicoAnita Dewi, Fitri Rahmayanti, Haidar Bagir et al.Natural remedies are increasingly being used as alternatives to conventional medicine, and their popularity is growing. The fig plant (Ficus carica L.), which is known to contain secondary metabolites such as alkaloids, flavonoids, phenolics, terpenoids, steroids, and saponins, has the potential to act as an immunomodulator. The purpose of this study was to determine the content of flavonoid compounds based … …OnLine Journal of Biological Sciences, Vol. 23, Issue 1 · 19 Jan 2023 · 6,232 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleIn Vitro Immunomodulatory and Cytotoxic Potentials of Faloak (Sterculia quadrifida R.Br.) BarkTriana Hertiani, Purwantiningsih, Aji Winanta et al.Faloak (Sterculia quadrifida R.Br., Sterculiaceae) is an Indonesia indigenous plant widely used as a traditional remedy for various health complaints. This study aimed to explore the immunomodulatory and cytotoxicity potentials of Faloak bark by using in vitro techniques. Barks was extracted using water, ethanol and ethanol: water (1:1) separately. Colorimetric analysis was used for the determination of the total phenolic … …OnLine Journal of Biological Sciences, Vol. 19, Issue 4 · 6 Nov 2019 · 8,059 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleImmunomodulatory and In vivo Antiplasmodial Activities of Propolis ExtractsSyamsudin, Rita Marleta Dewi, KusmardiProblem statement: Malaria caused by various species of prozoan parasites, Plasmodium. The exact mechanism of humoral immunity in eliminating Plasmodium is not completely understood. However, an antimalarial antibody is strongly suspected to play important role in immunity. The purpose of this research was to evaluate the immunomodulator and antiplasmodial activities of Indonesian propolis extracts. Approach: Thirty male BALB/c mice weighing … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 3 · 30 Sep 2009 · 7,801 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMolecular Characterization and in Silico Analysis of Phytochemical Compounds from Plants with Immunomodulatory PotentialHermin Pancasakti Kusumaningrum, Rejeki Siti Ferniah, Siti Nur Jannah et al.The immune system works to protect the body against foreign antigens from microorganisms and abnormal cells. The use of herbal plants as immunomodulators are used to prevent disease attacks. TNFα and interleukin-6 are pro-inflammatory immune systems that cause disease in uncontrolled synthesis. Herbal plants as inhibitors of TNFα and interleukin-6 need to be identified molecularly to reduce the occurrence of … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 27 Nov 2025 · 1,954 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleA Polysaccharide-Rich Fraction Derived from Oviductus ranae with Antioxidant and Immunomodulatory PotentialsXiaojin Yu, Xinyu Wang, Xinyu Liu et al.Oviductus ranae, an animal-based traditional Chinese medicinal material listed in Chinese Pharmacopeia is widely consumed as tonic, approximately twenty Oviductus ranae-related functional foods have been approved on the market by National Medical Products Administration in China. Proteins are well-defined bioconstituents in Oviductus ranae, little information is availabe on its polysaccharides. In present work, a Polysaccharide-Rich fraction (POR-3) was fractionated from … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 3 · 13 Sep 2020 · 6,620 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleImmunomodulatory Activity of Argan Oil (Argania spinosa L)Youcef Necib, Ahlem Bahi, Sakina Zerizer et al.Immunomodulatory activity of Argan oil was evaluated on phagocytic activity by carbon clearance test. Adult Albinos Wistar rats randomly divided into four groups, were the first was served as a control, while animals of treatment group were given Argan oil at dose of: 2.5, 5 and 10 mL kg-1 by gavage respectively 10 days before injected the carbon ink suspension. … …American Journal of Immunology, Vol. 9, Issue 3 · 20 Aug 2013 · 6,932 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePreliminary Study on Immunomodulatory Effect of Sarang-Semut Tubers Myrmecodia tuberosa and Myrmecodia pendensTriana Hertiani, Ediati Sasmito, Sumardi, Maria UlfahProblem Statement: Sarang-Semut tubers, Myrmecodia tuberosa and M. pendens (Rubiaceae) are both medicinal plants originating from Papua which have broad range of therapeutic values including those to improve vitality. Nevertheless, no scientific proof is available so far on their immunomodulatory effect. The purpose of this study was to reveal the potency of Sarang-Semut tubers as immunomodulatory agent by evaluating their … …OnLine Journal of Biological Sciences, Vol. 10, Issue 3 · 30 Sep 2010 · 13,397 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAntibiotic Susceptibility and Immunomodulatory Potential of Chosen Bacterial PathogensM. Sujatha, P. Dhasarathan, B. KarthickProblem statement: Antibiotic susceptibility is still the best way for bacterial pathogen escape mechanism against immunity. Approach: In the present investigation, bacterial pathogens like Staphylococcus aureus, Escherichia coli, Aeromonas hydrophila, Klebsiella and Pseudomonas aeruginosa were used to screen antibiotic susceptibility and immunomodulatory potential. Results: All the test pathogens were sensitive to all the test antibiotics 11±2 mm) except penicillin. The … …American Journal of Immunology, Vol. 6, Issue 2 · 30 Jun 2010 · 7,829 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleImmunomodulatory and Antioxidant Effects of Stachys Japonica Miq. Ethanol Extract on Cyclophosphamide-Induced Immunosuppressed Mice and its Phytochemical CompositionXueping Jiang, Jianglong He, Yanjun Chen, Fang WangStachys japonica Miq. is an edible wild botanical drug and a traditional medicine in China. This study focused on examining the phytochemical profile and antioxidant properties of the ethanol extract of S. japonica Miq (SJEE) in vitro, as well as its immunomodulatory and antioxidant activities in cyclophosphamide (Cy)-induced immunosuppressed mice. The SJEE was analysed by UPLC-HRMS/MS. 36 Polyphenols, including flavonoids, … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 1 · 13 Apr 2026 · 1,449 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleImmunomodulatory and Antioxidant Activities of Selenium-Enriched Polysaccharides from Epimedium and Isatis IndigoticaRui Zhang, Jin Li, Jiajia ZhouThis study aims to investigate the effects of selenium modification on polysaccharides derived from two traditional Chinese medicinal herbs-Epimedium (Yinyanghuo) and Isatis root (Banlangen)-in enhancing immune function and antioxidant activity. The purpose is to explore the relationship between structure and function, providing a theoretical basis for the development of efficient plant-based functional antioxidants. Polysaccharides were extracted using an optimized enzymatic … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 3 Feb 2026 · 1,933 accessesView PDFCite