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7 articles for “hippocampal neurons”
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Research ArticleOpen accessPhrase in the titleCocaine Exposure Results in Formation of Dendritic Varicosity in Rat Primary Hippocampal NeuronsHonghong Yao, Crystal Bethel-Brown, Anil Kumar, Shilpa BuchProblem statement: It has been well documented that drugs of abuse such as cocaine can cause enhanced progression of HIV-Associated Neuropathological Disorders (HAND), the underlying mechanisms mediating these effects remain poorly understood. Approach: In present study, we explored the impact of cocaine exposure (I and 10 μM) on the dendritic beading in rat primary hippocampal neurons. Using the approach of … …American Journal of Infectious Diseases, Vol. 5, Issue 1 · 31 Mar 2009 · 7,889 accessesView PDFCite
CorrigendumOpen accessPhrase in the titleCorrigendum: Cocaine Exposure Results in Formation of Dendritic Varicosity in Rat Primary Hippocampal NeuronsHonghong Yao, Crystal Bethel-Brown, Shilpa BuchCorrection to: American Journal of Infectious Diseases http://doi.org/10.3844/ajidsp.2009.26.30, published online 2009; updated 08 February 2021 The authors have recently noticed that the representative image of MAP2 immunostaining in the control group in Figure 3A was incorrectly chosen. This error was inadvertently caused during the assembly of the images due to our negligence in the process of reformatting our manuscript. Original … …American Journal of Infectious Diseases, Vol. 17, Issue 1 · 8 Feb 2021 · 6,416 accessesView PDFCite
Research ArticleOpen accessIn the abstractHippocampal Pyramidal Cell Degeneration and Changes in Creb Protein in Datura stramonium Treated RatsPeter Etim Ekanem, Dare S. Sunday, Sunday Abba, Amanuel TesfayDatura Stramonium (DS) is a tropical shrub which is available worldwide. It has various uses and is often used to increase the intoxication of certain beverages. The seeds of this plant are very toxic but are commonly smoked in like manner as tobacco. The present study investigated the potential harmful effects of DS on pyramidal cells and CREB protein in … …Neuroscience International, Vol. 6, Issue 2 · 17 Sep 2015 · 7,062 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Stress Effects of Kaempferia parviflora in Immobilization Subjected RatsJintanaporn Wattanathorn, Terdthai Tong-un, Supaporn Muchimapura et al.It is well known that intense and prolonged stress can produce hippocampal neuronal damage and cognitive impairments, few studies have investigated possible ways to prevent its deleterious effects. Here, we investigated the neuroprotective effects of a Thai traditional herb, Kaempferia Parviflora (KP) extract, commonly known as Kra-Chai-Dum, on learning and memory loss and the induction of neurodegeneration in the hippocampus … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 1 · 14 May 2013 · 8,677 accessesView PDFCite
Research ArticleOpen accessIn the abstractMulberry Fruit Mitigates Alcohol Neurotoxicity and Memory Impairment Induced by Chronic Alcohol IntakeJintanaporn Wattanathorn, Nattaporn Phunchago, Supaporn Muchimapura et al.Problem statement: To date, the therapeutic strategy efficacy against memory impairment induced by alcohol intoxication is still limited. The novel therapeutic strategy which is easy to approach, less toxic and less cost is required. Based on the role of oxidative stress in memory impairment induced by alcohol, the neuroprotective effect of substance possessing antioxidant has gained much attention. Therefore, we … …American Journal of Applied Sciences, Vol. 9, Issue 4 · 8 Feb 2012 · 9,328 accessesView PDFCite
Research ArticleOpen accessIn the abstractHormetic and Non-Hormetic Dose-Response Functions in Stress Effects on Memory and Synaptic Plasticity: Issues and MechanismsPhillip R. Zoladz, David M. DiamondOver a century of behavioral research has shown that stress can exert both positive and negative effects on memory. We have explored the idea that the complex effects of stress on learning and memory can be characterized by hormetic- and non-hormetic dose-response functions, in which stress may either stimulate or impair brain memory mechanisms, depending, in part, on the timing … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 8,184 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Pathology of Alzheimer Disease Elicits an In Vivo Immunological ResponseDavid J. Bonda, Kate M. Webber, Sandra L. Siedlak et al.The mechanism(s) responsible for the loss of neurons that characterizes Alzheimer disease is incompletely understood. Nonetheless, there is considerable evidence suggestive of immune abnormalities coupled to alterations in blood-brain barrier permeability that likely play a key role in both the etiology and progression of the disease. To examine these issues further, this study was designed to examine the presence of … …American Journal of Immunology, Vol. 3, Issue 1 · 30 Jun 2007 · 7,115 accessesView PDFCite