3 articles for “genotoxic effects”

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Research ArticleOpen accessIn the keywordsGenotoxic Profile of Motor Garage WorkersNandan M. Shastri, Hemlata PantProblem statement: One way to study the effects on an exposed population is to conduct monitoring studies, using relevant biological parameters with a short term manifestation, such as cytogenetic analysis express the damages to the DNA or to the chromosomes resulting from exposure can be identified. The present study was thus designed to elucidate the effect motor garage environment on … …American Journal of Infectious Diseases, Vol. 7, Issue 3 · 15 Oct 2011 · 8,001 accessesView PDF Cite

Review ArticleOpen accessIn the abstractSelected Genotoxic Impurities Profiling During WFI Qualification to Control Carcinogenesis in Large Volume ParenteralsMohabbat UllahWater For Injections (WFI) which is the main vehicle of Large Volume Parenterals (LVPs) should be free from trace amount of genotoxic impurities. This review gives emphasis on quantification of genotoxic trace metals during qualification of WFI in LVPs manufacturing unit. According to ICH guidelines, impurities related to drug substances are classified into three main categories: Organic impurities, inorganic (elemental) … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 1 · 27 May 2015 · 7,708 accessesView PDF Cite

Research ArticleOpen accessIn the abstractInduction of Micronuclei in Mice Lymphocytes Exposed to Microwave and TolueneS. B. Mortazavi, A. Safari, A. Khavanin et al.Increasing applications of microwave radiation are of great concern with regard to public health. Several studies have been conducted detect effects of microwave exposure genetic material leading to negative or questionable results. The Micronucleus (MN) assay which is proved to be a useful method for detection of radiation exposure-induced cytogenetic damage was used in the present study to investigate the … …American Journal of Applied Sciences, Vol. 2, Issue 9 · 30 Sep 2005 · 6,614 accessesView PDF Cite