6 articles for “gastric ulceration”

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Research ArticleOpen accessPhrase in the titleThe Evaluation of Proton Pump Inhibitor Bioactive Fraction DLBS2411 from Cinnamomum burmannii (Nees & T. Nees) in Animal Model of Gastric Ulceration HealingFlorensia Nailufar, Raymond Rubianto TjandrawinataDLBS2411 is a bioactive fraction from Cinnamomum burmannii that is believed to possess anti-ulceration activity. In this study acetic acid was administered to induce gastric ulcer. Rats were divided into six groups: Healthy animals, untreated animals (acetic acid-induced), treatment group of BAF DLBS2411 25 mg kg-1 Body Weight (BW), BAF DLBS2411 50 mg kg-1 BW and positive control group of … …American Journal of Pharmacology and Toxicology, Vol. 12, Issue 4 · 28 Feb 2018 · 9,939 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsCytoprotective Effect of UlGen, a Polyherbal Formulation against Physical and Chemical Factor Induced Gastric Ulcers in Wister Albino RatsT. S. Muralidhar, Anna Balaji, Chinmay Bandopadhyay, S. L. ShanthaProblem statement: UlGen, a Polyherbal formulation, was investigated for its possible Ulcero-protective activity in ulcerogen and Cold-restraint stress induced Wister rats (Rattus rattus). Oral administration of UlGen, at a dose of 800 mg kg-1 significantly protected the onset of cold-resistance stress induced ulcerations. Approach: It significantly inhibited gastric ulceration induced by alcohol and aspirin. Control group: Alcohol 80% induced ulcer … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 3 · 30 Sep 2009 · 8,180 accessesView PDF Cite

Case ReportOpen accessIn the abstractSurvival Following Severe Paraquat Poisoning a Case Study from the Andaman and Nicobar IslandsShiv Shankar Singh, Colin Sanchez, Prasan Kumar PandaParaquat poisoning continues to pose a significant public health challenge in the Andaman and Nicobar Islands, largely due to its alarmingly high mortality rate. In this report, we present the case of a 39-year-old male farmer who ingested 30 mL of paraquat with the intent of suicide. Initially, the patient underwent prompt gastric lavage and exhibited relative stability. Upon admission, … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 22 Jan 2025 · 10,605 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEfficacy of the Administration of a Natural Feed Supplement in the Management of Equine Gastric Ulcer Syndrome in 7 Sport Horses: A Field TrialStucchi Luca, Zucca Enrica, Serra Alessia et al.Equine Gastric Ulcer Syndrome (EGUS) is one of the most common causes of poor performance in the equine patient and affects more than 90% of Standardbred and Thoroughbred racehorses in training. Nowadays, the principal therapeutic options for EGUS treatment include antiacids such as histamine receptor antagonists and proton pump inhibitors. Recently, many studies concerning feed supplements to treat and prevent … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 3 · 20 Jun 2017 · 9,071 accessesView PDF Cite

Research ArticleOpen accessIn the abstractMELATONIN PROTECTS THE INTEGRITY OF GASTRIC STRUCTURE FROM A STERILE TISSUE INJURY AND AUGMENTS BOTH MONONUCLEAR AND POLYMORPHONUCLEAR PERIPHERAL BLOOD CELLS INDUCED BY THE INJURY IN WISTAR ALBINO RATSBahjat Al-AniPeptic ulcer is a common upper gastrointestinal disease that remains a major public health problem. Gastric ulceration caused by Nonsteroidal Anti-Inflammatory Drugs (NSAID), stress and alcohol are the common causes of gastric ulcer formation in humans following helicobacter pylori bacterial infection of the stomach. The neurohormone, melatonin was reported to protect against NSAID- and stress-induced gastric lesions. We sought to … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 17 Mar 2014 · 7,227 accessesView PDF Cite

Research ArticleOpen accessIn the abstractGastroprotective Effect and Safety Assessment of Zanthoxylum Zanthoxyloides (Lam) Waterm Root Bark ExtractAlex Boye, George Asumeng Koffuor, Johnson Nyarko Boampong et al.Problem statement: Gastrointestinal ulcers account significantly for morbidity and mortality in Ghana. The study therefore investigated the gastroprotective effect of an ethanolic root bark extract of Zanthoxylum zanthxyloides and its safety for us. Approach: Gastric ulceration was induced in Sprague-Dawley rats with Indomethacin (25 mg kg-1, p.o) and was treated with 150, 250, or 500 mg kg-1 of the extract, … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 2 · 7 Aug 2012 · 8,495 accessesView PDF Cite