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7 articles for “erythropoietin”
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Research ArticleOpen accessEvery word in the titleThe Effects of Recombinant Human Erythropoietin and Tamoxifen on Growth and Angiogenesis of Mammary Tumor in Sprague-Dawley RatA. K. Sairah, A. Rasedee, O. Sheikh et al.Problem statement: Erythropoietin receptor (EPOR) has been detected in breast cancer cells and speculated to be involved in cancer growth, viability and angiogenesis. This has risen suspicious that EPO administration may enhance the severity of cancer. Approach: This study was undertaken to determine the effects of rHuEPO, Tamoxifen and their combination on the growth and angiogenesis of mammary tumor. Female … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 1 · 31 Mar 2009 · 7,804 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleErythropoietin-Like Effects of Dihydroartemisinin in Wistar Albino RatsUtoh-Nedosa Uchechukwu Anastasia, Nedosa Kenechi Stanislaus, Onyedibe Ikenna KennethArtemisinin drugs were active during the intra-erythrocytic stage of malaria parasite infection. The activity of artemisinin and synthetic endoperoxides was related to their interaction with heme. The electrophillic intermediate formed from artemisinin in the presence of heme alkylates the protein portion of hemoglobin preferentially to the heme portion. Problem statement: Since there might be an interaction between artemisinin and the … …American Journal of Agricultural and Biological Sciences, Vol. 6, Issue 4 · 9 Dec 2011 · 7,785 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleThe Ovario-Protective Effect of Erythropoietin against Oxidative Damage Associated with Reperfusion Following Ovarian Torsion in RatSayyah-Melli Manizheh, Kazemi-Shishvan Maryamalsadat, Solaimani-Rad Jafar et al.Problem statement: To show the effect of recombinant Erythropoietin (rhEPO) on the ovarian viability and histology in the twisted ischemic ovaries in rats, followed by detorsion. Approach: An experimental study was conducted in primate clinic of the School of Medicine, Tabriz University of Medical Sciences from Dec. 2008 to Apr. 2009. Forty, 4 month old Wistar rats are cased in … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 1 · 26 Apr 2011 · 7,846 accessesView PDFCite
Research ArticleOpen accessIn the keywordsA Study on Erythrocytic Determination of Anemic Condition among Human Immunodeficiency Virus Sero PositivesM. Andrew Pradeep, M. Thiruvalluvan, V. DhamodharanProblem statement: Acquired Immuno Deficiency Syndrome (AIDS) is growing health hazard throughout the world. In developing countries like India anemia is highly prevalent in the population due to the malnourished condition apart, HIV infection is one among the major cause of anemia. The outcome of certain infectious diseases including HIV is worse when the host is malnourished. HIV infection is … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 7,419 accessesView PDFCite
Research ArticleOpen accessIn the keywordsDetermination of Iron Deficiency among Human Immunodeficiency Virus Sero PositivesM. A. Pradeep, M. Thiruvalluvan, K. Aarthy, J. M. MaryProblem statement: Iron is an important dietary mineral and involves in various body functions. In humans, iron is an essential component of proteins involved in oxygen transport. It is also essential for the regulation of cell growth and differentiation. Iron and its binding protein have immune regulatory properties and shifting of immune regulatory balances by iron excess or deficiency may … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 7,020 accessesView PDFCite
Research ArticleOpen accessIn the abstractCross Talk between Iron Regulatory Proteins and Proinflammatory Molecules in Ovarian Cancer Patients Based on Menopausal StatusHaritha Padannapurath Manoj, Sudha Kuthethur, Reshma Kumarchandra et al.Micronutrient iron is postulated to contribute to the initiation of cancer mainly by the formation of Reactive Oxygen Species (ROS), the key signaling molecules of inflammatory reactions. Iron may also cause elevation of MMP9, a gelatinase responsible for remodeling extracellular matrix in cancer cells through the ROS pathway. Estrogen the hormone which decreases markedly in post menopause is also known … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 31 May 2024 · 4,491 accessesView PDFCite
Research ArticleOpen accessIn the abstractRandomized Clinical Stroke Trials in 2009Meheroz H. RabadiProblem statement: Stroke ranks as the leading cause of serious, long-term disability and death world-wide. It is estimated direct and indirect cost of stroke for 2009 was $68.9 billion. Approach: The objective of this review was to examine the effectiveness of emerging pharmacotherapy’s in patients with acute (≤2 weeks), sub-acute (2-12 weeks) and chronic (≥12 weeks) stroke studied in Randomized … …Current Research in Medicine, Vol. 1, Issue 1 · 30 Jun 2010 · 7,243 accessesView PDFCite