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14 articles for “computational biology”

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Review ArticleOpen accessPhrase in the titleBig Data and its Future in Computational Biology: A Literature ReviewIman Ahmed ElSayed, Kamal ElDahshan, Hesham Hefny, Eman Karam ElSayedBig data technologies are used majorly for computational biology research nowadays due to the emerge of massive amounts of biological data that have been generated and collected at an unprecedented speed and scale and with different structures. As an example, the processing of billions of DNA sequence data per day represents the new generation of sequencing technologies. It is expected … …Journal of Computer Science, Vol. 17, Issue 12 · 31 Dec 2021 · 6,598 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleA Feasibility Study of Challenges and Opportunities in Computational Biology: A Malaysian PerspectiveR. J.A. Richard, N. SriraamThe term computational biology refers to the knowledge derived from a computer analysis of biological data that includes identification of genes in DNA sequence of different organisms, prediction of structural and functional mechanism of proteins, feature extraction and classification of genomics and proteomics. Computational biology is a rapidly developing branch of science and is highly interdisciplinary, using techniques and Concepts … …American Journal of Applied Sciences, Vol. 2, Issue 9 · 30 Sep 2005 · 6,924 accessesView PDFCite
Research ArticleOpen accessIn the keywordsBioinformatics-Assisted Microbiological Research: Tasks, Developments and Upcoming ChallengesDhananjaya P. Singh, Ratna Prabha, Anil Rai, Dilip K. AroraProblem statement: Bioinformatics in the present day microbiological research is an inevitable subject area that encompasses biological resources and high end computational skills to unravel the coded and encrypted information within the life. We have produced a brief account of the developments and tasks in the subject and upcoming challenges in the subject. The area has seen tremendous developmental pattern … …Current Research in Bioinformatics, Vol. 1, Issue 1 · 23 Jan 2012 · 14,793 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite
Research ArticleOpen accessIn the abstractMetabolic Potential Versus Genome SizeAtanas Todorov Atanasov, Dimitar Todorov ValevAlberch, P. (1983). Development and Evolution: Embryos, Genes, and Evolution. The Developmental-Genetic Basis of Evolutionary Change. Science, 221(4607), 257–258. https://doi.org/10.1126/science.221.4607.257 Andrews, C. B., Mackenzie, S. A., & Gregory, T. R. (2009). Genome size and wing parameters in passerine birds. Proceedings of the Royal Society B, 276(1654), 55–61. https://doi.org/10.1098/rspb.2008.1012 Atanasov, A. T. (2005). The linear alometric relationship between total metabolic energy … …Physics International, Vol. 13, Issue 1 · 15 Jun 2022 · 7,229 accessesView PDFCite
Research ArticleOpen accessIn the abstractSlime Mould Reproduction: A New Optimization Algorithm for Constrained Engineering ProblemsRajalakshmi Sakthivel, Kanmani SelvaduraiIn recent explorations of biologically inspired optimization strategies, the Slime Mould Reproduction (SMR) algorithm emerges as an innovative meta-heuristic optimization technique. This algorithm is deeply rooted in the reproductive dynamics observed in slime molds, particularly the intricate balance these organisms strike between local and global spore dispersal. By replicating this balance, the SMR algorithm deftly navigates between exploration and exploitation … …Journal of Computer Science, Vol. 20, Issue 1 · 21 Dec 2023 · 5,943 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtein Secondary Structure Prediction using Hybrid Recurrent Neural NetworksRomana Rahman Ema, Akhi Khatun, Md. Alam Hossain et al.The most important and challenging problem in bioinformatics is protein secondary structure prediction. The molecules of all protein organisms have three-dimensional (primary, secondary, 3-D) structures which are completely recognized by the sequence of amino acids. Protein secondary structure attributes to the polypeptide backbone of the local configuration of proteins. Most generally, the second-level prediction is indicated such as: If there … …Journal of Computer Science, Vol. 18, Issue 7 · 14 Jul 2022 · 7,332 accessesView PDFCite
Research ArticleOpen accessIn the abstractComputing MDR-Game with Applications to Real DataJimbo Henri Claver, Takeru Suzuki, Jesus Pascal et al.Originally developed for probability and statistic purposes, Multiple Dice Rolling (MDR) game turns out to be useful for many other applications such as complex biological systems and medical research. It has been mainly used to estimate system states that cannot be observed directly. MDR game is affected by noise and fluctuations. It is widely agreed that noise in dynamic systems … …Journal of Computer Science, Vol. 14, Issue 7 · 17 Jul 2018 · 7,789 accessesView PDFCite
Research ArticleOpen accessIn the abstractImproving Protein 3D Structure Prediction Accuracy using Dense Regions Areas of Secondary Structures in the Contact MapAmer F. Al-Badarneh, Mohammad A. Khalil, Mo'taz A. Al-HamiProblem Statement: The protein folding problem is a fundamental problem in structural molecular biology. This problem describes how a protein is transformed from its primary sequence (i.e., amino acid sequence) into the three dimensional structure (3D structure) for this sequence that determines the function of the protein. The 3D structure of a protein can be represented using a square symmetrical … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 4 · 31 Dec 2008 · 7,533 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Survey of Protein Fold Recognition AlgorithmsMohammed Said Abual-Rub, Rosni AbdullahProblem statement: Predicting the tertiary structure of proteins from their linear sequence is really a big challenge in biology. This challenge is related to the fact that the traditional computational methods are not powerful enough to search for the correct structure in the huge conformational space. This inadequate capability of the computational methods, however, is a major obstacle in facing … …Journal of Computer Science, Vol. 4, Issue 9 · 30 Sep 2008 · 6,877 accessesView PDFCite