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Author

Shigeto Tohma

Clinical Research Center for Allergy and Rheumatology, Japan
1 article in our journals

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Research ArticleOpen accessMast Cells Inhibit CD8+ T Cell-Mediated Rejection of a Malignant Fibrous Histiocytoma-Like Tumor: Involvement of Fas-Fas Ligand AxisHiroshi Furukawa, Hiroshi Kitazawa, Izumi Kaneko et al.Problem statement: Mast cells develop from bone marrow-derived progenitor cells and are distributed in the skin or mucosa where they play proinflammatory roles in the first line of defense. Since some tumors in humans and experimental animals exhibited infiltration of increased mast cells, we investigated the contribution of mast cells to the override of tumor rejection. Approach: MRL/N-1 cells are … …American Journal of Immunology, Vol. 5, Issue 3 · 30 Sep 2009 · 7,670 accessesView PDFCite