Author

Krishna Murti

National Institute of Pharmaceutical Education and Research, India

16 articles in our journals

Articles where this person is an author, newest first. People are matched by their name as printed (no ORCID iD is recorded for them), not by name alone; search the name as text to find namesakes too.

Research ArticleOpen accessExploration of Antidiabetic and Hypolipidemic Activity of Roots of Croton ZambesicusPrakash Kumar, Rahul Kumar, Manoj Kumar Rastogi, Krishna MurtiThe aim of this study was to investigate the potential antidiabetic and hypolipidaemic effects of aqueous and ethanolic extracts of roots of Croton zambesicus in alloxan induced diabetic models to ascertain its pharmacological applicability. The roots of Croton zambesicus were collected, dried and extracted. The phytochemical screening as well as Median Lethal Dose determination (LD50) was done. The ethanolic extract … …American Journal of Pharmacology and Toxicology, Vol. 12, Issue 1 · 12 Jun 2017 · 7,856 accessesView PDF Cite

Research ArticleOpen accessSelf Medication with Antibiotics among Medical and Pharmacy Students in North IndiaBiplab Pal, Krishna Murti, Ashok Kumar Gupta et al.Self medication practices among the medical and paramedical professionals have been reported in many countries, however, very limited research was done exclusively on antibiotic in North India. This study was designed to assess the prevalence and pattern of antibiotic usage for self diagnosed diseases among the medical and pharmacy students. This was a questionnaire based cross sectional study conducted among … …Current Research in Medicine, Vol. 7, Issue 2 · 30 Dec 2016 · 13,707 accessesView PDF Cite

Research ArticleOpen accessPrescription Pattern of Anti-Hypertensive Drugs in Adherence to JNC- 7 GuidelinesKrishna Murti, M. Arif Khan, Akalanka Dey et al.The main objective of the present study to investigate the utilization pattern of antihypertensive drugs in hypertensive patients and to find out whether the prescription pattern is in adherence with the JNC7 guidelines for the management of hypertension. A prospective study was conducted and drug utilization data were collected from 137 hypertensive patients who were attended as Out Patient Department … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 1 · 2 Jun 2015 · 8,277 accessesView PDF Cite

Research ArticleOpen accessNEWER DRUGS FOR VISCERAL LEISHMANIASIS: A REVIEWKrishna Pandey, Dharmendra Singh, Sanjiva Bimal et al.Visceral Leishmaniasis (VL) is one of the most neglected tropical diseases worldwide. The diagnosis and treatment of this disease is quite complex. Sodium Antimony Gluconate (SAG) which used to be a very effective treatment has now developed resistance and is potentially a cardio-toxic drug. Pentamidine has now been discarded because of adverse effect of diabetes mellitus. Amphotericin-B is an effective … …American Journal of Infectious Diseases, Vol. 10, Issue 2 · 5 May 2014 · 7,135 accessesView PDF Cite

Research ArticleOpen accessPOST KALA-AZAR DERMAL LEISHMANIASIS WITH ULCERATION ON FOOT: AN ATYPICAL CASE PRESENTATION SUCCESSFULLY TREATED WITH MILTEFOSINEVidyanand Rabi Das, Dharmendra Singh, Krishna Murti et al.Visceral Leishmaniasis (VL) or Kala-Azar (KA) is highly endemic in the Indian subcontinent particularly in Bihar. Post Kala-azar Dermal Leishmaniasis (PKDL) is a known reservoir for leishmania parasites for transmission of VL. The kala-azar elimination program was launched by the government of three countries of the Indian subcontinent in the year 2005, which aims to eliminate kala-azar by 2015 and … …American Journal of Infectious Diseases, Vol. 10, Issue 2 · 2 Apr 2014 · 7,586 accessesView PDF Cite

Research ArticleOpen accessASSOCIATION OF TESTOSTERONE AND CHOLESTEROL LEVEL IN MODULATION OF IMMUNITY AND SEVERITY OF DISEASE IN VISCERAL LEISHMANIASIS PATIENTS-A PRELIMINARY STUDYKrishna Pandey, Dharmendra Singh, Sanjiva Bimal et al.Males are more prone to Visceral Leishmaniasis (VL) as compared to females. The role of androgens in host defence against Leishmania and other pathogens is of considerable interest. This study was aimed to understand a baseline mechanistic understanding of the pathogenesis of visceral leishmaniasis with respect to testosterone. We examined the relationship between serum testosterone and cholesterol levels, antigen induced … …American Journal of Immunology, Vol. 10, Issue 1 · 25 Mar 2014 · 7,076 accessesView PDF Cite

Research ArticleOpen accessCOMPLICATED CASE OF RHEUMATIC HEART DISEASE; UNEXPLORED FOR YEARSM. Arif Khan, Raj Kishore Pandey, Tarique Nadeem et al.Rheumatic heart disease is a one of the very common heart problem commonly prevalent among the children of developing countries, may occur in adults in their fourties also, if undiagnosed in early ages, similar in symptoms to ’rheumatism’ but quite difficult to diagnose or are often misdiagnosed. The main objective of this article is to make acquainted about the disease … …OnLine Journal of Biological Sciences, Vol. 14, Issue 1 · 23 Jan 2014 · 7,800 accessesView PDF Cite

Research ArticleOpen accessFormulation and Evaluation of Ficus benghalensis and Ficus racemosa Aquoues ExtractsDivya Kiran, Upendra Kumar, Krishna Murti, Manish KaushikWe intended to develop a desired ointment for treatment of wound. Main objective of this study was to formulate the ointment with different ointment bases having good consistency, better diffusion and antiseptic properties. To assess the efficacy of uniformity, viscosity, diffusivity, rheology, stability, spreadability, permeability and other physical characteristics were evaluated. Two Formulations, formulation A (Aq. extract of Ficus racemosa) … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 3 · 21 Sep 2013 · 7,409 accessesView PDF Cite

Research ArticleOpen accessExploration of Healing Promoting Potentials of Leaves of Morus alba L. in Albino RatsManish Kaushik, Aditi Kaushik, Krishna MurtiTo establish the wound healing activity of aqueous and ethanolic extract of roots of Morus alba. Two models were performed to evaluate the wound healing activity i.e., Incision and Excision model. In incision model the parameter which was carried out was breaking strength of wounded skin. In excision model percentage wound contraction and period of epithelialization was established for both … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 3 · 4 Sep 2013 · 7,452 accessesView PDF Cite

Research ArticleOpen accessAdverse Effects of Amphotericin B in Patients of Visceral Leishmaniasis: A Short Survey at Research Hospital PatnaSurabhi Bhatnagar, Shweta, Krishna Murti et al.Leishmaniasis is a disease caused by Leishmania parasite. Leishmania currently affects 12 million people in 98 countries, with an annual incidence of approximately two million new cases. Leishmaniasis is a devastating disease impairing economic productivity and impeding socioeconomic development. The objective of this article was to study the adverse effects of amphotericin B in patients of visceral leishmaniasis which was … …Current Research in Virology, Vol. 2, Issue 1 · 29 Jul 2013 · 6,817 accessesView PDF Cite