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Research ArticleOpen accessAutomatic Calibration of Frequency Compensation System in Computer-Controlled Patch-Clamp AmplifierJun Xiong, Gang Hu, Anlian QuComputer-controlled patch-clamp amplifier is a digitally controlled analog device used to record the cellular ion channel currents in electrophysiology research. The inherent bandwidth and performance of the headstage is limited by the stray capacitance and distributed capacitance across the feedback resistors. In order to effectively improve the performance of the headstage, the paper advanced a simplified automatic calibration method of … …Journal of Computer Science, Vol. 3, Issue 10 · 31 Oct 2007 · 6,814 accessesView PDF Cite