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4 articles for “antiplasmodial”
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Research ArticleOpen accessEvery word in the titleIN VIVO ANTIPLASMODIAL ACTIVITY AND ACUTE TOXICITY OF STANDARDIZED EXTRACT OF EURYCOMA LONGIFOLIA JACK. ROOT TRADITIONALLY USED TO TREAT MALARIAEti Nurwening Sholikhah, Mahardika Agus Wijayanti, MustofaA series of studies has been conducted to prove the Eurycoma longifolia Jack. root as an antimalarial. However, the in vivo antiplasmodial activity of E. longifolia Jack. root standardized extract and its lethal dose 50% (LD50) values is unknown. In vivo antiplasmodial activity was conducted on Plasmodium berghei infected Swiss mice as malaria model with 4-day suppression methods. Sixty mice … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 27 Dec 2013 · 7,732 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleImmunomodulatory and In vivo Antiplasmodial Activities of Propolis ExtractsSyamsudin, Rita Marleta Dewi, KusmardiProblem statement: Malaria caused by various species of prozoan parasites, Plasmodium. The exact mechanism of humoral immunity in eliminating Plasmodium is not completely understood. However, an antimalarial antibody is strongly suspected to play important role in immunity. The purpose of this research was to evaluate the immunomodulator and antiplasmodial activities of Indonesian propolis extracts. Approach: Thirty male BALB/c mice weighing … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 3 · 30 Sep 2009 · 7,801 accessesView PDFCite
Research ArticleOpen accessIn the keywordsStage Specificity of Eurycomanone Isolated from Eurycoma longifolia on Plasmodium falciparum CyclesEti Nurwening Sholikhah, Mahardika Agus Wijayanti, Ratna Asmah Susidarti et al.Eurycomanone is the most active compounds in the roots of Eurycoma longifolia and shown to have in vitro antiplasmodial activity. However, the stage of Plasmodium falciparum cycles which are sensitive to eurycomanone have not been investigated. This study was conducted to investigate stage specificity of eurycomanone at various stages of P. falciparum life cycles. Stage specificity of eurycomanone at various … …American Journal of Pharmacology and Toxicology, Vol. 11, Issue 1 · 16 Jan 2016 · 7,739 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIn vitro Anti Plasmodial Activity of Enicostemma littoraleSanket Soni, Sarita GuptaProblem statement: Malaria is a prevalent disease in India. The problem of drug resistance is worsening. Hence, new effective and affordable antimalarial drugs are very much needed. The long-established use of quinine and the more recent introduction of artemisinin as highly effective anti malarials demonstrate that plant species are an important resource for the discovery of new anti malarial agents. … …American Journal of Infectious Diseases, Vol. 5, Issue 3 · 30 Sep 2009 · 7,707 accessesView PDFCite