4 articles for “adenoma”

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Research ArticleOpen accessEvery word in the titleThe Interplay between p53 and p21 Tumor Suppressor Proteins in the Transformation of Colorectal Adenoma to CarcinomaA.S. Abdulamir, R.R. Hafidh, L.K. Mahdi et al.This study was carried out for evaluating the interplay of p53, p21 and Ki-67 proteins along the colorectal adenoma-carcinoma oncogenic transformation sequel. Therefore, Fifty colorectal cancer and 14 adenoma patients were involved. The histopathological expression of p53, p21 and Ki-67 proteins was evaluated by immunohistochemistry assay. The results revealed that remarkable overexpression of p53 protein was seen in the tumorous … …American Journal of Immunology, Vol. 4, Issue 2 · 30 Jun 2008 · 7,740 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsHepatic and Renal Histological Alterations Induced by Topical Hydroquinone AdministrationBashir M. Jarrar, Maher M. Alenezi, Abdullah Al-Hiri, Yazun JarrarProblem statement: Although the regulatory agencies of the United States and Europe banned hydroquinone in cosmetics skin lightening but it is still used in most of Middle East countries, including Saudi Arabia. Few studies were carried out on the histological alterations of hydroquinone on kidney and liver. Approach: The present study was carried out to investigate the histological alterations in … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 1 · 7 Apr 2012 · 9,653 accessesView PDF Cite

EditorialOpen accessIn the abstractAssociation between Infective Endocarditis and Premalignant Colorectal LesionsCarles FalcesThe association between Infective Endocarditis (IE) and Colorectal Cancer (CRC) has been known for more than 50 years. The microorganisms in which this association has been described are Streptococcus gallolyticus (formerly Streptococcus bovis) (Corredoira-Sánchez et al., 2012; Boleij et al., 2011), in different subspecies and, more recently, Enterococcus faecalis (Pericàs et al., 2016; 2017; Escolà-Vergé et al., 2020; Pericàs et … …American Journal of Infectious Diseases, Vol. 17, Issue 3 · 10 Jun 2021 · 11,559 accessesView PDF Cite

Research ArticleOpen accessIn the abstractRelationship between Streptococcus gallolyticus Infective Endocarditis and Pre-Neoplastic Colorectal LesionsPau Vilardell, Sergio Moral, Josep Maria Frigola et al.Colorectal cancer is associated with Infective Endocarditis (IE) due to specific gut pathogens, such as Streptococcus gallolyticus subspecies, that use tumor presence as a point of blood entry. However, the association between Streptococcus gallolyticus related IE and pre-cancerous colorectal lesions like dysplastic adenomas is unclear. Seventy-one patients diagnosed with IE who underwent colonoscopy in the extension study during admission were … …American Journal of Infectious Diseases, Vol. 17, Issue 3 · 28 May 2021 · 7,131 accessesView PDF Cite