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17 articles for “acute toxicity test”
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Research ArticleOpen accessIn the keywordsAntidepressant-Like Activity of Banana Peel Extract in MiceTan Pei Tee, Halijah HassanProblem statement: Depressed mood, loss of interest or pleasure, feeling guilty, low selfesteem, sleep disturbance, loss of appetite, low energy and poor concentration are the characteristics of depression. This common mental disorder can occur in anyone regardless of genders, ages and backgrounds. People counteract it with psychotherapy and medications. Alternatively, some patients use herbal remedies as treatments. Recently, natural herbal … …Current Research in Medicine, Vol. 2, Issue 2 · 1 Oct 2011 · 18,671 accessesView PDFCite
Research ArticleOpen accessIn the keywordsToxicity Testing and the Effect of Landfill Leachate in Malaysia on Behavior of Common Carp (Cyprinus carpio L., 1758; Pisces, Cyprinidae)Jaffar Y.M. Alkassasbeh, Lee Yook Heng, Salmijah SurifProblem Statement: Landfill leachate had been implicated in environmental pollution, developmental anomalies, birth defect and surface and groundwater pollution worldwide. This study has been conducted to determine the toxicity of landfill leachate from three different landfills in Malaysia on fry common carp (Cyprinus carpio L., 1758; Pisces, Cyprinidae) in combination with some physico-chemical parameters analysis. Approach: Leachates were collected from … …American Journal of Environmental Sciences, Vol. 5, Issue 3 · 30 Jun 2009 · 8,020 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Acute Oral Toxicity Induced by Tablets Based on Ethanolic Extract of Salvia dumetorum Leaves in Experimental RatsYana Levaya, Karakoz Badekova, Mussa Zholdasbayev, Gayane AtazhanovaThe aim of this study was to assess the acute oral toxicity of a solid dosage form based on Salvia dumetorum Andrz. ex Besser leaf extract (SDT5) in experimental rats. Acute toxicity was evaluated over a 14-day observation period following a single oral administration at three dose levels (500 mg/kg, 1000 mg/kg, and 2000 mg/kg), prepared in 0.5 mL of … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 23 Jun 2026 · 1,241 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Role of Ganoderma lucidum Polysaccharides Against Stress Induced by Heavy Metals in Caenorhabditis elegansHuixiu Ma, Dehui Dai, Guicai Chen, Weilian HuAli, H., Khan, E., & Ilahi, I. (2019). Environmental Chemistry and Ecotoxicology of Hazardous Heavy Metals: Environmental Persistence, Toxicity, and Bioaccumulation. Journal of Chemistry, 2019, 6730305. https://doi.org/10.1155/2019/6730305 Aljerf, L., & Aljerf, N. (2023). Food products quality and nutrition in relation to public. Balancing health and disease. Progress in Nutrition, 25(1), e2023024. https://doi.org/10.23751/pn.v25i1.13928 Aljerf, L., Williams, M., Ajong, A. B., Onydinma, … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 2 · 18 May 2024 · 6,947 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn-Vivo Evaluation of Hexavalent Chromium Induced DNA Damage by Alkaline Comet Assay and Oxidative Stress in Catla catlaKantha Deivi Arunachalam, Sathesh Kumar Annamalai, Jaya Krishna KuruvaIn the present study, the acute toxicity of Chromium in fingerlings of Catla catla, an Indian major carp, was evaluated with renewal bioassay method. In vivo studies were designed to assess the extent of Micronucleus Assay, Comet Assay under the exposure of common heavy-metal compounds, namely, Chromium Nitrate, using Catla catla (2n = 20), as a test model. The laboratory … …American Journal of Environmental Sciences, Vol. 9, Issue 6 · 15 Jan 2014 · 7,196 accessesView PDFCite
Research ArticleOpen accessIn the abstractIN VIVO ANTIPLASMODIAL ACTIVITY AND ACUTE TOXICITY OF STANDARDIZED EXTRACT OF EURYCOMA LONGIFOLIA JACK. ROOT TRADITIONALLY USED TO TREAT MALARIAEti Nurwening Sholikhah, Mahardika Agus Wijayanti, MustofaA series of studies has been conducted to prove the Eurycoma longifolia Jack. root as an antimalarial. However, the in vivo antiplasmodial activity of E. longifolia Jack. root standardized extract and its lethal dose 50% (LD50) values is unknown. In vivo antiplasmodial activity was conducted on Plasmodium berghei infected Swiss mice as malaria model with 4-day suppression methods. Sixty mice … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 27 Dec 2013 · 7,732 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Antimalaria Activity and Acute Toxicity of Xetospongia spSyamsudin Abdillah, Rahmatul Wahida Ahmad, Yatnita Parama Cita, Noriah Mohd NoorWe investigated the in vivo activity of extract of Xetospongia sp against Plasmodium berghei Strain ANKA and acute toxicity in mice. The ethanolic extracts of the Xetospongia sp (50-400 mg kg-1 day) were screened for blood schizonticidal against P. berghei strain ANKA in mice during early and established infections. Acute toxicity of extracts of Xetospongia sp at the dose 5000 … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 2 · 2 Sep 2013 · 7,796 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Acute Toxicity and Neuropharmacological Activities of PM-52Wipawee Thukhum-Mee, Jintanaporn Wattanathorn, Supaporn MuchimapuraThe neuropsychological disorders are increasing their importance nowadays. Unfortunately, the therapeutic efficacy is still not in satisfaction level. Therefore, the novel agents that are effective, safe, cheap and easy to approach are in required. Therefore, we aimed to determine the neuropharmacological activities of PM52, the novel herbal supplement. We had developed the PM52, a novel product comprising of Cissampelas pariera … …American Journal of Agricultural and Biological Sciences, Vol. 8, Issue 2 · 27 May 2013 · 7,351 accessesView PDFCite
Research ArticleOpen accessIn the abstractACUTE TOXICITY STUDY OF TOMATO POMACE EXTRACT IN RODENTSupaporn Muchimapura, Terdthai Tong-Un, Jintanaporn Wattanathorn et al.Tomato and tomato products are considered to be healthy food for the human diet. Although tomatoes have been widely studied for their phenolic content, less emphasize has been laid on toxicological effect of this plant. Thus, the purpose of the present study is to determine the acute toxicity effect of Lycopersicon esculentum, or commonly known as tomato, was administered orally … …OnLine Journal of Biological Sciences, Vol. 13, Issue 1 · 24 Feb 2013 · 7,683 accessesView PDFCite