Research ArticleOpen accessIn the author namesExploring the Relationship Between Skin Barrier Function, Sensitivity, and Repair MechanismsXiaoqing Yan, Yusong Shi, Jiguang YangFor healthy skin, the skin's barrier function must remain maintained. Many different molecular while immunological signaling mechanisms are involved in skin barrier control. The control of a healthy skin barrier, particularly acid mantle maintenance and proper amounts of ceramides, may help dermatologists develop remedies for skin barrier disruption disorders. In contrast, new medicines could focus on signaling pathways to offer … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,905 accessesView PDFCite
Research ArticleOpen accessIn the author namesEpigenetic Regulation of Extracellular Matrix Remodeling in Skin Aging: Mechanisms and InteractionsJiguang Yang, Yusong Shi, Xiaoqing YanSkin aging results from complex interactions between genetic factors, environmental stressors, and epigenetic modifications that regulate extracellular matrix (ECM) remodeling. Accumulation of senescent cells impairs tissue regeneration through mechanisms including telomere shortening, reactive oxygen species accumulation, and ultraviolet (UV) radiation exposure. While epigenetic pathways regulate skin homeostasis, regeneration, and senescence, the specific epigenetic changes occurring during UV exposure, chronological aging, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,461 accessesView PDFCite
Research ArticleOpen accessIn the author namesExpression and Induction Optimization of Mucor Circinelloides Lipase in Escherichia ColiYueping Yang, Yao Zhang et al.Microbial lipases serve as versatile biocatalysts for modifying lipid substrates, enabling diverse biotechnological applications spanning food technology, renewable energy production, and pharmaceutical sectors. Genomic analysis of Mucor circinelloides WJ11 revealed multiple lipase-encoding genes, with WJ_23 successfully cloned and heterologously expressed in Escherichia coli. Since the lipase expression was mainly concentrated in the cell pellets, appropriate induction strategies had been investigated … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 13 Jun 2025 · 5,987 accessesView PDFCite
Research ArticleOpen accessIn the author namesExtraction, Partial Identification and Bioactivities of Total Flavonoids from Carex meyeriana KunthHongbiao Wang, Penghui Wang, Xiudong Yang et al.To date, knowledge associated with extraction, chemical constituents and bioactivities of Total Flavonoids from Carex meyeriana Kunth (TFCMK) that remains unclear. Therefore, this paper was designed to optimize the ethanol reflux extraction method by response surface methodology and determine the chemical constituents by Liquid Phase-Mass Spectrometry (HPLC-MS); additionally, the bioactivities including antioxidant, antibacterial and hemolysis test were also explored. The … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 3 · 7 Aug 2019 · 7,525 accessesView PDFCite
Research ArticleOpen accessIn the author namesOptimization of Cellulase-Assisted Extraction of Total Flavonoids from Corn Bract and Evaluation of Antioxidant and Antibacterial AactivitiesYang Zhang, Jing Lu, Leijie Ben et al.Corn bract is a corn-based agricultural waste material that distributed worldwide. In present work, response surface methodology was applied to optimize the cellulase-assisted extraction of Total Flavonoids from Corn Bract (TFCB), the in vitro antioxidant and antibacterial as well as the in vivo antioxidant activities of TFCB were investigated. Results showed that the optimal conditions for TFCB extraction were as … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 2 · 18 May 2019 · 8,505 accessesView PDFCite
Research ArticleOpen accessIn the author namesComparative Analysis of UGT1A9 Genetic Polymorphisms between Chinese Han and Tibetan PopulationsWei Yan, Jian Cui, Yuewen Wang et al.Although various polymorphisms have been identified in the UGT1A9 gene in the main sorts of ethnic groups in the world, no investigations have been focused on the Chinese Tibetan populations and the comparison between Chinese Tibetan and Han populations to date. This study was designed to systematically compare genetic differences between the two populations. We investigated the functional regions of … …Current Research in Medicine, Vol. 3, Issue 2 · 23 Aug 2012 · 7,647 accessesView PDFCite
Research ArticleOpen accessIn the author namesThe Design and Implementation of Parallel Digital Library Management SystemYang Yan, Li Jianzhong, Kan ZhongliangAs the number of documents in digital library grows, it becomes increasingly difficult to store, manage the large amount of documents and finding requested relevant documents by users. Parallel Digital Library management System (PDLS) is used for this purpose. PDLS is a general tool for building and managing digital libraries of all kinds of documents to meet user needs. It … …Journal of Computer Science, Vol. 1, Issue 2 · 30 Jun 2005 · 7,286 accessesView PDFCite
Research ArticleOpen accessIn the author namesInterest-based Recommendation in Digital LibraryYan Yang, Jian Zhong LiWith the huge amount and large variety of information available in a digital library, it’s becoming harder and harder for users to identify and get hold of their interested documents. To alleviate the difficulty, personalized recommendation techniques have been developed. Current recommendation techniques rely on similarity between documents. In our work, recommendations are made based on three factors: similarity between … …Journal of Computer Science, Vol. 1, Issue 1 · 31 Mar 2005 · 7,015 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Role of Ganoderma lucidum Polysaccharides Against Stress Induced by Heavy Metals in Caenorhabditis elegansHuixiu Ma, Dehui Dai, Guicai Chen, Weilian HuAli, H., Khan, E., & Ilahi, I. (2019). Environmental Chemistry and Ecotoxicology of Hazardous Heavy Metals: Environmental Persistence, Toxicity, and Bioaccumulation. Journal of Chemistry, 2019, 6730305. https://doi.org/10.1155/2019/6730305 Aljerf, L., & Aljerf, N. (2023). Food products quality and nutrition in relation to public. Balancing health and disease. Progress in Nutrition, 25(1), e2023024. https://doi.org/10.23751/pn.v25i1.13928 Aljerf, L., Williams, M., Ajong, A. B., Onydinma, … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 2 · 18 May 2024 · 6,949 accessesView PDFCite