Research ArticleOpen accessIn the keywordsANTIOBESITY EFFECTS OF HUMAN SOLUBLE LEPTIN IN MICE NOURISHED WITH A HIGH-FAT/HIGH FRUCTOSE DIETB. Chimal-Vega, N. Paniagua-Castro, J. C. Perez-Rebollar et al.Leptin is a hormone that regulates energy balance. Since its discovery two decades ago, several efforts have been made to fully understand its role in metabolic regulation of feeding behavior, reproduction, glucose homeostasis, immune function, bone formation, lipid metabolism, among others. Its use as a therapeutic option in obese patients is still limited due to the syndrome known as Leptin … …American Journal of Agricultural and Biological Sciences, Vol. 9, Issue 3 · 9 Jul 2014 · 7,386 accessesView PDFCite