Case ReportOpen accessIn the keywordsPortal Vein Thrombosis: A Saga of two Nebulous EtiologiesAshwin Parchani, Manjunath Totaganti, Prasan Kumar Panda, Sunil Kumar KSPortal Vein Thrombosis (PVT) is the most prevalent cause of extrahepatic portal vein obstruction. Cirrhosis, inherited procoagulant conditions (such as Factor V Leiden, Antithrombin III deficiency, etc.), myeloproliferative neoplasms, hepatocellular carcinoma and operative manipulation of the portal vein are all common causes of portal vein thrombosis. Even though a diagnosis is usually made, more than 25% of patients have no … …American Journal of Infectious Diseases, Vol. 18, Issue 1 · 26 Mar 2022 · 6,180 accessesView PDFCite
Review ArticleOpen accessIn the abstractJAK Inhibitors for Rheumatoid Arthritis: Assessing Efficacy and Safety in TreatmentAnastasia V. Poznyak, Varvara A Orekhova, Natalia Vladimirovna Elizova et al.Rheumatoid Arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation, progressive joint destruction, and systemic complications. Dysregulated cytokine signaling through the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway plays a central role in RA pathogenesis, making JAK inhibitors an important therapeutic option. Tofacitinib, baricitinib, and upadacitinib are oral targeted synthetic disease-modifying antirheumatic drugs that interfere with … …OnLine Journal of Biological Sciences, Vol. 26, Issue 4 · 8 Oct 2026 · 412 accessesView PDFCite