2 articles for “UPLC-Q-Orbitrap-MS”

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Research ArticleOpen accessEvery word in the titleUPLC-Q-Exactive Orbitrap-MS Analysis of Anchusa italica Retz. Flowers: Molecular Docking, Dynamics Modeling, and Pharmacokinetics for Cardiovascular DiseaseLinyang Wang, Yan Chen, Ainiwaer Aikemu, Shuge TianThis study builds on prior UPLC-Q-Exactive Orbit rap-MS analyses of Anchusa italica Retz. Flowers (Airfs) to explore their anti-cardiovascular mechanis·ms and key bioactive markers. UPLC-Q-Exactive Orbitrap-MS identified 30 major compounds, including polyphenols and flavonoids with strong antioxidant activity. The potential active ingredients were then screened using Lipinski's rule of five, and a network pharmacology method was employed to construct an … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 25 Oct 2025 · 2,599 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsQualitative Analysis of the Chemical Composition of Cinnamomum tamala leaves and Biological ActivityQianwen Gong, Pin Chen, Linyang Wang, Shuge TianCinnamomum tamala (Buch.-Ham.) Nees and Ebermaier. (Lauraceae) is a less explored medicinal plant in Uyghur medicine, with limited knowledge about its non-volatile compounds. We utilized chemical pre-screening in conjunction with UPLC-Q-Orbitrap-MS to analyze the phytochemical makeup of C. tamala leaves. Total polyphenols were measured using the Folin-Ciocalteu method, while total flavonoids were quantified through NaNO2-Al (NO3)3 colorimetric analysis across four … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 3 · 21 Sep 2026 · 659 accessesView PDF Cite