Research ArticleOpen accessIn the keywordsDecoding Lung Cancer: PLAU as a Critical Driver and Diagnostic MarkerStanley Cho, Min Gyeong KimLung cancer remains a leading cause of cancer-related mortality, and understanding its underlying molecular mechanisms is critical for developing targeted therapies. We developed a novel tool called the Transcriptome-TCGA Integration (TTI), which combines in vitro transcriptome data with clinical datasets from the Cancer Genome Atlas (TCGA). TTI allows for the identification of key genes and pathways involved in lung cancer, … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 15 Feb 2026 · 1,424 accessesView PDFCite
Research ArticleOpen accessIn the abstractCPF-Net: Cross-modal CT and Pathology Guided Feature Learning for CT-based Lung Cancer Subtype ClassificationPeizhi Tan, Debiao YanAccurate classification of lung cancer subtypes from CT images remains challenging due to the subtle radiological differences between adenocarcinoma (LUAD) and squamous cell carcinoma (LUSC). We propose CPF-Net, a deep learning framework that integrates CT and pathological information through a Linear Spatial Reduction Attention (LSRA) module. The framework processes whole slide images using a modified CTransPath architecture for pathological feature … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 23 Jan 2026 · 1,856 accessesView PDFCite