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721 articles for “T cells”
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Research ArticleOpen accessEvery word in the titleCytotoxicity Evaluation of Curcumin-FITC Conjugates in Granulosa Cells Isolated from Ovarian Follicles of Kampung Chicken (Gallus gallus domesticus)Sukarman Hadi Jaya Putra, Mansur S, UmarudinLinking curcumin to fluorescein isothiocyanate (FITC) results in a hybrid fluorescent marker (curcumin-FITC) that exhibits improved stability and sensitivity in detection. This study sought to evaluate the biological safety and cytotoxic effects of curcumin-FITC on granulosa cells obtained from ovarian follicles (2-5 mm, F1-F4 stage) of Kampung chickens. Following fluorescent labeling with different concentrations of curcumin-FITC (0-100 μg/mL), cell viability … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 14 May 2026 · 1,497 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffect of an IgY-Based Immunomodulatory Combo on the Internalization of Staphylococcus aureus by HC11 Cells: Preliminary in vitro Studies IIZarete Jatna Isha, Adu-Addai BenjaminInfectious mastitis is a common disease of cattle of economic significance. Clinical mastitis affects between 20 to 25% of dairy cows each year. Staphylococcus aureus (SA) causes an estimated 10-11.7% of bovine infectious mastitis cases in the US, reducing milk production, increasing morbidity, increasing antibiotic use and milk waste, and fueling premature culling. The SA mastitis cure rate varies from … …American Journal of Infectious Diseases, Vol. 21, Issue 1 · 1 Feb 2026 · 2,814 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleInflammatory Effects of Co-Exposure to Heavy Metals (Cd and Pb) and Respiratory Viruses (229E, OC43, and H3N2) on IL-6 and IL-8 Responses in U87 Glioblastoma CellsHyeokjun Yun, Qian-Wen Wang, Jae Kyung KimCo-exposure to heavy metals and viruses can pose threats to cellular health by increasing cytotoxicity and inflammatory cytokine expression. We aimed to elucidate the interactions between these factors inhuman glioblastoma cells (U87). U87 cells were exposed to influenza A virus (H3N2), coronaviruses OC43 and 229E, and heavy metals Cd and Pb. Cell viability and cytotoxicity were assessed through WST-8 and … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 5 Jul 2025 · 5,505 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAdipose-Derived Canine Mesenchymal Stem Cells in PLAY® MediaArjun Kulkarni, Bhavana N. V., Teena Mary Thomas et al.In veterinary medicine, stem cell-based therapies present promise for addressing orthopedic and degenerative conditions in canines. Mesenchymal Stem Cells (MSCs) possess unique regenerative, immunomodulatory, and differentiation capabilities. However, their efficacy relies on optimal in-vitro conditions. Prolonged expansion over passages leads to a gradual loss of stem cell traits, highlighting the importance of optimized culture conditions and media supplements. This study … …American Journal of Animal and Veterinary Sciences, Vol. 19, Issue 3 · 13 Jul 2024 · 5,598 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleResponses of Neural Cells (U87) to HCoV-229E and HCoV-OC43 InfectionsEun Ju Oh, Jae-Sik Jeon, Qian-Wen Wang, Jae Kyung KimRespiratory viruses, such as Coronaviruses (CoVs), can be neuroinvasive and exacerbate neurological pathologies via their capacity for direct viral replication and/or by inducing excessive host immune responses in the Central Nervous System (CNS). HCoV-229E is a primary COVID-19 and HCoV-OC43 is a beta COVID-19 belonging to the same genus as SARS-CoV-2 and both can cause acute infections in glioblastoma, neuroblastoma, … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 2 · 8 Jun 2023 · 5,181 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEarly Responses of Neural Cells (U87) to Particulate Matter Exposure: Cell Viability and Cytokine ConcentrationJae-Sik Jeon, Eun Ju Oh, Qian-Wen Wang, Jae Kyung KimParticulate Matter (PM) has a significant impact on human health and increases the risk of respiratory diseases. PM exposure is linked to various illnesses, including cardiovascular diseases, cancer, neurological diseases, and pregnancy complications, and contributes to both mortality and morbidity globally. PM can also influence the autonomic nervous system. The evidence suggests that the likelihood of developing lung cancer continually … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 1 · 20 Feb 2023 · 5,450 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleExpression of Exosome-Derived MicroRNAs miR-21 and miR-135 are Differentially Regulated Among Dental Pulp Stem CellsMatthew Hunsaker, Brandon Richards, Adelle Fuller et al.Dental Pulp Stem Cells (DPSCs) are a type of mesenchymal stem cell that has the potential to differentiate into various types of cells and tissue. Previous research has demonstrated that DPSCs can be easily accessed and isolated from both permanent and deciduous teeth, such as wisdom teeth or third molars, although there is less information available about the mechanisms and … …Current Research in Medicine, Vol. 11, Issue 1 · 10 Jan 2023 · 10,533 accessesView PDFCite
Short CommunicationsOpen accessEvery word in the titleCytotoxicity and Apoptosis-Induction Potential of Fraction F3 from Fruits of Bersama engleriana (Melanthaceae) against Human Cervical Cancer CellsMichèle Stella Majoumouo et al.Cervical cancer is one of the most life-threatening malignancies worldwide, despite intensive research for more efficacious chemotherapeutic agents. Recent efforts geared towards eradicating the scourge of cancer have embodied a major surge of interest in natural products as promising lead molecules in pharmaceutical development and therapeutic translation. Consequently, this study aimed to assess the cytotoxicity of a previously identified plant … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 5 Dec 2022 · 5,292 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffect of Cinnamomum cassia Stem-Bark Extracts on the Synthesis and Secretion of Insulin in RIN-m5F CellsAnanias Hodi Kgopa, Sebolaishi Doris Makhubela, Motetelo Alfred Mogale, Leshweni Jerry ShaiCinnamomum cassia (C. cassia) crude stem-bark extracts possess some hypoglycemic properties through inhibiting the uptake of glucose by the intestines and/or enhancing insulin sensitivity. To further investigate the mechanism through which the hypoglycemic effect is exerted, this research explored the influence of the extracts of the crude stem-bark of C. cassia, with various polarities, on particular aspects of glucose consumption … …OnLine Journal of Biological Sciences, Vol. 22, Issue 2 · 5 Apr 2022 · 5,784 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleStructural Organization of Vitelline Cells of Trematode with Undifferentiated Body of Azygia Lucii (Muller, 1776)Rimma Meyramovna Ualiyeva, Sayan Berikovich Zhangazin, Indira Bulatovna AltayevaIt is known that the class Trematoda includes exclusively parasitic forms of flatworms. In this regard, they have formed a variety of morphological and functional adaptations to a parasitic lifestyle. One of them is the colossal fecundity, which provides the possibility of rapid and wide settlement and detection of hosts. Therefore, the study of the sexual reproduction of helminths is … …OnLine Journal of Biological Sciences, Vol. 22, Issue 1 · 26 Jan 2022 · 6,378 accessesView PDFCite