Research ArticleOpen accessIn the keywordsInterplay of Cytokines and Chemokines in the Pathogenesis of Systemic Lupus ErythematosusDilip Shah, Ajay Wanchu, Archana BhatnagarProblem statement: Dysbalance of T-helper-cell (Th) cytokines and chemokines was suggested to contribute to the pathogenesis of Systemic Lupus Erythematosus (SLE). Recent reports suggest the involvement of cytokines and chemokines in the pathogenesis of SLE, but their relationship with each other and particularly in the severity of disease, was not yet understood. We analyzed the interaction between cytokines and chemokines … …American Journal of Immunology, Vol. 7, Issue 3 · 21 Dec 2011 · 8,161 accessesView PDFCite
Research ArticleOpen accessIn the abstractExploring the Role of Immune Complexes in Essential HypertensionIvan MilosevicEssential hypertension is a rise of arterial blood pressure whose etiology is unknown. Immune complexes are complexes created by the binding of an antibody to the antigen. They are also called circulating immune complexes because of its precipitation in peripheral blood vessels, commonly on the places of their bifurcation and the places of higher blood pressure (glomerules of kidney or … …American Journal of Immunology, Vol. 18, Issue 1 · 2 Nov 2022 · 9,974 accessesView PDFCite
EditorialOpen accessIn the abstractGLUTATHIONE: A POSSIBLE LINK TO AUTOPHAGY IN SYSTEMIC LUPUS ERYTHEMATOSUSDilip Shah, Swapan K. NathIncreased free radical formation and altered redox state are of fundamental importance in the pathogenesis of autoimmune diseases including Systemic Lupus Erythematos (SLE). Free radicals are mainly derived from oxygen (Reactive Oxygen Species/ROS) and nitrogen (Reactive Nitrogen Species/RNS) at mitochondria, cellular membranes and the endoplasmic reticulum membrane as physiological responses to a variety of internal and external stress (Shah et … …American Journal of Immunology, Vol. 10, Issue 3 · 3 Sep 2014 · 12,773 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordRelationship between Fetuin-A and Systemic Lupus Erythematosus as a Predictor Marker for AtherosclerosisOsama F. Mosa, Ibrahim H. Mohamad, Magdi M. SalamaProblem statement: Associations between serum levels of fetuin-A, C3 complement, calcium × phosphate product and calcification risk index and lipid profile in SLE patients were established. However, the mechanism of accelerated atherosclerosis accompanied with SLE remains elusive. We therefore turned to investigate the association between Fetuin-A, disease activity and accelerated atherosclerosis in patients with SLE. Approach: Serum blood samples were … …Current Research in Medicine, Vol. 3, Issue 2 · 15 Sep 2012 · 7,777 accessesView PDFCite