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3 articles for “Shanbin Chen”

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Research ArticleOpen accessIn the author namesDihydroartemisinin Attenuates HBV-Induced Proliferation and Migration in LO2 cells via EMT Pathway ModulationYingde Nong, Caifang Ma, Wei Huang et al.Dihydroartemisinin (DHA), a derivative of artemisinin, possesses well-documented anti-inflammatory properties. This study investigated the inhibitory effects of DHA on hepatitis B virus (HBV)-induced cellular alterations in LO2 cells and elucidated underlying molecular mechanisms. Serum interleukin-6 (IL-6) levels were measured in HBV patients and analyzed for correlations with HBsAg, anti-HBs, and HBeAg. In vitro, LO2 cells were infected with clinical HBV … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 8 Jan 2026 · 2,071 accessesView PDFCite
Research ArticleOpen accessIn the author namesFerulic Acid in Chinese Herbal Medicine: Regulating Autophagy for Oxidative Damage ReductionZhiyuan Lv, Qiaozhen Zhao, Shanbin Chen et al.Ferulic Acid (FA) is the primary functional component in herbal plants and traditional fermented foods. To comprehend the mechanism of action of ferulic acid, in terms of its regulation of autophagy, antioxidants and the inhibition of inflammatory pathways, the study was conducted. Oxidatively damaged human-derived hepatocytes were treated with FA and the processing concentration of FA is from 50-800 μm. … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 2 · 1 Jun 2024 · 5,483 accessesView PDFCite
Research ArticleOpen accessIn the author namesNuclear Factor Erythroid-2-Related Factor 2 (Nrf2) Signalling Pathway and Apoptosis Impact on the Effect of Tetramethylpyrazine against H2O2-Damage in Human Hepatic Cell Line (LO2 Cells)Songbo Guo, Xinglin Han, Baoguo Sun et al.As an active component in traditional Chineseherbal medicine, Tetramethylpyrazine (TMP)played a critical role in the treatment of cardiovascular, cerebrovascular, andeye diseases. In this study, the TMP has obtained from the Chinese herbalmedicine Ligusticum chuanxiong and investigated the protective effects of TMPon oxidative damage in human LO2 cells with the treatment ofdifferent concentrations of TMP. The results showed that TMP reserved … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 3 · 6 Sep 2022 · 5,654 accessesView PDFCite