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7 articles for “Sedation”
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Research ArticleOpen accessIn the keywordsMethadone and Dexmedetomidine Combination as Premedicant Agents for Ovariectomy in CatsH. Tayari, I. Vannozzi, G. Breghi, A. BrigantiThe purpose of this study was to assess sedative and analgesic effects produced by the association of methadone and dexmedetomidine, administered intramuscularly as premedication for ovariectomy in cats. Twenty-four healthy cats were enrolled in the study. The values of heart and respiratory rate were recorded as Tbase. Cats received methadone 0.5 mg kg-1 and dexmedetomidine 5 mcg kg-1 IM. Sedation … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 2 · 27 Jun 2015 · 8,400 accessesView PDFCite
Research ArticleOpen accessIn the abstractSevoflurane Requirements Concerning Continuous Infusion of Dexmedetomidine in RabbitsGissela Chisag, Jorge Moposita-Maiza, Andrés Guerrero, Jenny LozadaDexmedetomidine provides a satisfactory sedative and analgesic effect in balanced anaesthesia of small animals. In rabbits, it provides effective sedation and intravenous infusion of one or more drugs are commonly used to induce or maintain general anaesthesia. We aimed to evaluate the effect of continuous infusion of dexmedetomidine on the Minimum Alveolar Concentration (MAC) of sevoflurane and anaesthetic efficacy in … …American Journal of Animal and Veterinary Sciences, Vol. 20, Issue 1 · 14 May 2025 · 5,080 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnalytical Method Validation of Vilazodone with Spectrofluorimetric Detection in Rabbit PlasmaIrene Sartini, Marco Salvadori, Beata Łebkowska-Wieruszewska et al.Vilazodone (VLZ) is an antidepressant agent approved in 2011 by Food and Drug Administration (FDA) for the treatment of major depressive syndromes. Its chemical structure derives from trazodone which is used as an off-label drug for dogs and cats in order to induce sedation and reduce anxiety, behavioural and pre-and post-operative stress. VLZ could be a potentially useful compound in … …American Journal of Animal and Veterinary Sciences, Vol. 14, Issue 1 · 2 Apr 2019 · 7,740 accessesView PDFCite
Review ArticleOpen accessIn the abstractTrazodone: A Review of Its Pharmacological Properties and Its Off-Label Use in Dogs and CatsBunna Chea, Mario GiorgiTrazodone is approved by the Food and Drug Administration (FDA) for the treatment of depression and anxiety in humans, it can perform these functions due to its selective serotonin receptor antagonism and reuptake inhibition properties. Trazodone has not been approved for animals by the FDA but it is legally prescribed by veterinarians as an off-label drug for dogs and cats. … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 4 · 31 Oct 2017 · 10,858 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparative Evaluation of the Epidural Dexmedetomidine, Ketamine or Fentanyl in Combination with Bupivacaine in DogsEman M. Nour, Mahmoud Mahmoud Othman, Gamal I.A. Karrouf, Adel E.I. ZaghloulCastration is one of the most common procedure. It is a potential source of mild to moderate pain which is enough to induce inflammatory process, necessitate the incorporation of analgesics. This study was designed to evaluate the effect of epidural bupivacaine alone or in association with fentanyl, ketamine or dexmedetomidine on analgesia for the first 24 h post surgical castration. … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 4 · 8 Nov 2013 · 7,188 accessesView PDFCite
Research ArticleOpen accessIn the abstractQuantification of Zolpidem in Canine PlasmaMario Giorgi, Alessandra Gavazza, Hyoin YunProblem statement: Zolpidem is a non-benzodiazepine hypnotic agent currently used in human medicine. In contrast to benzodiazepines, zolpidem preferentially binds with the GABAA complex ϖ1 receptors while poorly interacting with the other ϖ receptor complexes. Recent studies have suggested that ZP may be used to initiate sedation and diminish severe anxiety responses in dogs. The aim of the present study … …American Journal of Animal and Veterinary Sciences, Vol. 7, Issue 1 · 19 Mar 2012 · 7,908 accessesView PDFCite
Research ArticleOpen accessIn the abstractOn Application of Carhart Atom Pairs to Predict Anticonvulsant ActivityAlan Talevi, Julian J. Prieto, Luis E. Bruno-Blanch, Eduardo CastroAbout 50 million people in the world suffer from epilepsy, especially in childhood, adolescence and old age. Available treatment fails to control epilepsy in up to 30% of affected people. In developing countries, however, the amount of patients that do not receive adequate treatment climbs up to 75%. Moreover, the new generation of antiepileptic drugs (AEDs) causes important central and … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 3 · 30 Sep 2006 · 6,857 accessesView PDFCite