Research ArticleOpen accessIn the author namesCA-LIME: A Collinearity-Aware LIME Framework for Reliable and Interpretable Explanations in Healthcare AIIdris Khan, Sachin BhoiteIn clinical tabular models, correlated biomarkers can make local explanations unstable even when predictive performance appears acceptable. This paper presents CA-LIME, a collinearity-aware extension of LIME built to address that failure mode directly. Five variations of CA-LIME Vanilla reference, VIF, PCA back projection, Ridge, and ElasticNet allow us to investigate how various correlation-control strategies alter explanation behavior. ILPD, Kaggle liver, … …Journal of Computer Science, Vol. 22, Issue 7 · 28 Jul 2026 · 813 accessesView PDFCite