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11 articles for “Red Blood Cell (RBC)”
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Research ArticleOpen accessIn the keywordsIn Vivo Neutralization of Naja nigricollis Venom by Uvaria chamaeOmale James, Ebiloma Unekwuojo Godwin, Idoko Grace OtiniUvaria chamae is a well known medicinal plant in Nigerian traditional medicine for the management of many diseases, but investigations concerning its pharmacological characteristics are rare. In this study, we evaluate its venom neutralizing properties against Naja nigricollis venom in rats. Freshly collected Uvaria chamae leaves were air dried, powdered and extracted in methanol. To study the antivenom properties, albino … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 3 · 21 Sep 2013 · 8,421 accessesView PDFCite
Research ArticleOpen accessIn the keywordsGastroprotective Effect and Safety Assessment of Zanthoxylum Zanthoxyloides (Lam) Waterm Root Bark ExtractAlex Boye, George Asumeng Koffuor, Johnson Nyarko Boampong et al.Problem statement: Gastrointestinal ulcers account significantly for morbidity and mortality in Ghana. The study therefore investigated the gastroprotective effect of an ethanolic root bark extract of Zanthoxylum zanthxyloides and its safety for us. Approach: Gastric ulceration was induced in Sprague-Dawley rats with Indomethacin (25 mg kg-1, p.o) and was treated with 150, 250, or 500 mg kg-1 of the extract, … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 2 · 7 Aug 2012 · 8,495 accessesView PDFCite
Research ArticleOpen accessIn the abstractHaemato-Biochemical Indices of Red Sokoto Goats Fed Various Levels of Earthworm Meal-Based DietsMoshood Adewale Belewu, Ling Shing Wong et al.Blood is essential to life and it is vital for the transportation of oxygen from the lungs to every cell of the body for metabolism purposes. Hence, blood samples were collected from thirty (30) healthy Red Sokoto goats fed an earthworm meal-based diet with ten goats per treatment constituting a replicate in a Completely Randomized design model to evaluate the … …OnLine Journal of Biological Sciences, Vol. 25, Issue 1 · 3 Dec 2024 · 4,963 accessesView PDFCite
Research ArticleOpen accessIn the abstractApplying Neural Network-Based Approach to Sickle Cell Disease-Related Pain ClassificationZacchaeus Omogbadegun, Israel Ogundele, Olufunke OladipupoSickle Cell Disease (SCD), an inherited Red Blood Cell (RBC) disorder, is characterized by anaemia, end-organ damage, unpredictable episodes of pain and early mortality. SCD affects 25% of people living in Central and West Africa causing life threatening “silent” strokes and lifelong damage. Nigeria accounts for 50% of SCD births worldwide (estimated 150,000 of 300,000 babies born with Symptomatic Sickle … …Journal of Computer Science, Vol. 15, Issue 6 · 28 Jun 2019 · 7,678 accessesView PDFCite
Research ArticleOpen accessIn the abstractProposed Insights in the Pharmaco-Dynamic Theory of Ascorbate Pro-Oxidant ActivityKheir Eddine Kerboua, Fatma Haiba, Fatima Bendjemia et al.Ascorbate pro-drug theory promising possible effective and nontoxic treatment is intensively examined and centered on the importance of both extracellular and intra-cellular effects of ascorbate. In this study, we sought to determine the in vitro cell responsiveness in a plasma free milieu with or without an extracellular catalyst and/or hydrogen peroxide. This project brought to light how ascorbic acid would … …OnLine Journal of Biological Sciences, Vol. 16, Issue 1 · 24 Nov 2015 · 6,966 accessesView PDFCite
Research ArticleOpen accessIn the abstractPROTECTIVE ROLE OF VITAMIN C AND GREEN TEA EXTRACT ON MALATHION-INDUCED HEPATOTOXICITY AND NEPHROTOXICITY IN RATSRabab R. Elzoghby, Ahlam F. Hamoda, A. Abdel-Fatah, Mona FaroukThe present study was designed to determine the modulating effect of green tea and vitamin C against adverse effects of malathion. Animals were divided into four groups 5 rats /group). Group one was used as a control. Group two given malathion (50 mg/kg/day; 1/50 of the LD50 for four weeks). Group three and Group four were given malathion (50 mg/kg/day; … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 3 · 22 Jul 2014 · 8,171 accessesView PDFCite
Research ArticleOpen accessIn the abstractABSENCE OF VISIBLE TOXIC EFFECTS ACCOMPANYING THE SHORT-TERM ADMINISTRATION OF AN AQUEOUS EXTRACT OF ALLIUM SATIVA LINN. IN MALE SPRAGUE-DAWLEY RATSJ. Asiedu-Gyekye Isaac, Awortwe Charles, A. Antwi DanielAllium sativum is cultivated in the northern part of Ghana and has gained widespread use as chemoprotective, in curing hypertension, impotence and erectile dysfunction. The multipurpose use together with its aphrodisiac activity has resulted in the widespread use of this plant medicine both in meals and as herbal medications. Safety assessment of this plant however is rare. The present study … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 30 Jan 2014 · 7,577 accessesView PDFCite
Research ArticleOpen accessIn the abstractAcute and Sub-acute Toxicity of Crataegus Aronia Syn. Azarolus (L.) Whole Plant Aqueous Extract in Wistar RatsAbdullah S. ShatoorProblem statement: Hawthorn comprises more than 200 species worldwide but very few species have been used medicinally. In Mediterranean region, the predominant species of the genus Crataegus is C. aronia syn. Azarolus (L). The extracts or tinctures prepared from the leaves, flowers and/or a fruit has been used traditionally for the treatment of different diseases including different cardiovascular problems. This … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 2 · 17 Aug 2011 · 14,660 accessesView PDFCite
Research ArticleOpen accessIn the abstractCamel's Milk Protects Against Cadmium Chloride-Induced Hypocromic Microcytic Anemia and Oxidative Stress in Red Blood Cells of White Albino RatsMohammad DallakProblem statement: Cadmium is a heavy metal of wide occupational and environmental contamination. In recent years, however, Cadmium has been implicated in the pathogenesis of several clinical disorders. One of the most frequently described problems in aluminum toxicity is anemia. Therefore, the present study was carried out to determine the effectiveness of Camel's milk in alleviating the toxicity of Aluminum … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 4 · 31 Dec 2009 · 8,683 accessesView PDFCite
Research ArticleOpen accessIn the abstractCamel's Milk Protects Against Aluminum Chloride-Induced Normocytic Normocromic Anemia, Lipid Peroxidation and Oxidative Stress in Erythrocytes of White Albino RatsFahaid Al-HashemProblem statement: Aluminum (Al) is an indifferent element from a toxicological point of view. In recent years, however, Al has been implicated in the pathogenesis of several clinical disorders. One of the most frequently described problem in aluminum toxicity is anemia. The present study was carried out to determine the effectiveness of Camel’s milk in alleviating the toxicity of aluminum … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 3 · 30 Sep 2009 · 8,021 accessesView PDFCite