5 articles for “Primitive Immune”

Research ArticleOpen accessIn the keywordsInnate and Adaptative Immunity in the Sea-Star Asterias RubensMichel LeclercThe axial organ of the sea star Asterias rubens is a primitive immune organ. The B-like cells, when stimulated by various antigens, produce antibody substances correlating with Mouse Ig Kappa genes. On the other hand elements of the innate immunity are present in Asterias rubens such as Toll-like receptors, interleukin receptors, complement components which contribute to initiate the «antibody factor». …American Journal of Immunology, Vol. 8, Issue 3 · 1 Sep 2012 · 7,903 accessesView PDF Cite

Research ArticleOpen accessIn the abstractLike an Invertebrate Primitive AntibodyMichel LeclercSpecific immune responses occur in an invertebrate: The sea star Asterias rubens. Sea star T and B lymphocytes are present in the axial organ and coopere with phagocytes and Complement components to produce a primitive antibody correlated to Igkappa genes and to complement genes: It could be composed of 4 kappa chains and present strong and highly significant homologies to … …American Journal of Immunology, Vol. 9, Issue 3 · 20 Aug 2013 · 7,043 accessesView PDF Cite

Research ArticleOpen accessIn the abstractA True &#34Candidate Ig Kappa Gene&#34 in the Sea-Star: Asterias rubens (Echinoderma)Michel Leclerc, Patricia Otten, Magne OsterasThe axial organ of the sea-star Asterias rubens is a primitive immune organ. The B-like cells, when stimulated by various antigens, produce antibody substances correlated with Ig Kappa gene. A candidate Ig kappa gene (IgK chain V-IV region S107B precursor) more convincing in term of genome was shown. …American Journal of Immunology, Vol. 9, Issue 3 · 20 Aug 2013 · 7,222 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEvidence of Interleukin Genes in the Sea-Star: Asterias rubens (Echinoderma)Michel Leclerc, Patricia OttenThe axial organ of the sea star Asterias rubens is a primitive immune organ the sea star T lymphocytes, when stimulated by various lectins, produce lymphokin-like substances with mitogenic properties as shown in earlier studies; they are correlated with Interleukin genes. …American Journal of Immunology, Vol. 9, Issue 2 · 22 Jun 2013 · 7,280 accessesView PDF Cite

Research ArticleOpen accessIn the abstractComplement Genes in the Asterids Comparisons with the Echinids (Echinoderma)Michel LeclercThe axial organ of the sea star Asterias rubens (Asterid) is a primitive immune organ. The B-like cells, when stimulated by various antigens, produce antibody substances correlating with ig kappa genes. On the other hand, component complement genes were found. For each component, one or several contigs were analysed. It is said that Asterias forbesi, another sea-star, in earlier results, … …American Journal of Immunology, Vol. 9, Issue 1 · 26 Feb 2013 · 7,472 accessesView PDF Cite