2 articles for “Polyketide Synthase (PKS)”

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Research ArticleOpen accessIn the keywordsBioactive Compounds from Sponge Associated Bacteria: Anticancer Activity and NRPS-PKS Gene Expression in Different Carbon SourcesJepri Agung Priyanto, Rika Indri Astuti, Jun Nomura, Aris Tri WahyudiSponge associated bacteria with diverse NRPS-PKS genes could be the alternative source of bioactive compounds. This study aimed to analyze the activity as well as the regulatory mechanism regarding the anticancer properties derived from these bacteria against cancer cell lines. Extraction of bacterial metabolites using ethyl acetate solvent resulted yield ranging from 0.003 to 0.016% (w/v). Six extracts of bacterial … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 4 · 5 Oct 2017 · 8,886 accessesView PDF Cite

Research ArticleOpen accessIn the abstractScreening and Characterization of Sponge-Associated Bacteria Producing Bioactive Compounds Anti-Vibrio sp.Aris Tri Wahyudi, Jepri Agung Priyanto, Wenang Maharsiwi, Rika Indri AstutiIn Indonesia, vibriosis is the main disease in shrimp. This disease is caused by Vibrio sp that may decrease the productivity of shrimp cultivation. Thus, exploration for new bioactive compounds as vibriosis biocontrol agent is necessary. Marine sponge-associated bacteria is one of many sources for bioactive compounds. The aim of this study was to screen marine sponge-associated bacteria producing anti-Vibrio … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 3 · 5 Oct 2018 · 10,357 accessesView PDF Cite