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24 articles for “Placebo group”
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Research ArticleOpen accessIn the keywordsBeneficial Effect of a Cellulose-Containing Chew Treat on Canine Periodontal Disease in a Double-Blind, Placebo-Controlled TrialA. C. Beynen, F. Van Altena, E. A. VisserProblem statement: There are indications that appropriate chew treats can contribute to the control of canine periodontal disease. It was reasoned that the incorporation of a cellulose fiber network into the treat may improve the efficacy, but for proof experimental data were required. Approach: A double-blind, placebo-controlled trial with privately owned dogs was carried out to assess the efficacy of … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 3 · 30 Sep 2010 · 8,256 accessesView PDFCite
Research ArticleOpen accessIn the keywordsWhat Else do Epileptic Data RevealRamalingam ShanmugamProblem statement: Aggregating and analyzing data of all patients using statistical methodologies as often done in macro sense would be not useful when physician’s professional interest was only to provide the best medical care to the patient. For this purpose, individual data of the involved patient should be analyzed and modeled in a micro sense for the physician to notice … …Current Research in Medicine, Vol. 2, Issue 1 · 29 Mar 2011 · 7,302 accessesView PDFCite
Research ArticleOpen accessIn the abstractβ-carotene Supplementation Does Not Improve Milk Yield and Milk Components of Saanen GoatsDominic Lado Marino Gore, Khoboso Christina LehloenyaWe hypothesized that supplementing goats with β-carotene would increase milk yield and improve milk quality. Therefore, the current study aimed at evaluating the effect of supplemental β-carotene on milk yield and milk components. Goats were divided into two groups, one group received β-carotene 100 and 50 mg/head/day before and during the drying off period, respectively, while the second group received … …American Journal of Animal and Veterinary Sciences, Vol. 15, Issue 2 · 19 May 2020 · 6,761 accessesView PDFCite
Research ArticleOpen accessIn the abstractSafety Assessment of Indigenous Probiotic Strain Lactobacillus plantarum Dad-13 Isolated from Dadih Using Sprague Dawley Rats as a ModelEndang S Rahayu, Ilzamha H Rusdan, Armita Athennia et al.Lactobacillus plantarum Dad-13 is a probiotic candidate from dadih, a traditional fermented buffalo milk from West Sumatera, Indonesia. This study aimed to evaluate safety aspects of L. plantarum Dad-13 in high dose consumption on Sprague Dawley rats. Two treatment groups were fed with 1011 CFU/mL/day of L. plantarum Dad-13 for 14 and 28 days respectively. Two placebo groups were fed … …American Journal of Pharmacology and Toxicology, Vol. 14, Issue 1 · 12 Nov 2019 · 10,134 accessesView PDFCite
Research ArticleOpen accessIn the abstractSildenafil in the Treatment of Postoperative Hypoxemia with High Resistance in Cyanotic Congenital Heart DiseaseZhou Jiawang, Lv Yong, Hu Zhendong et al.This study was designed to determine the effect of sildenafil treatment on postoperative hypoxemia with high resistance in cyanotic congenital heart disease. A total of 247 cases of cyanotic congenital heart disease were operated on from May 2006 to August 2014. Only 45 cases exhibited postoperative hypoxemia after symptomatic treatment. Sildenafil at doses of 0.30-5 mg/kg every 6 h was … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 3 · 1 Sep 2017 · 7,682 accessesView PDFCite
Review ArticleOpen accessIn the abstract"Ebola Ça Suffit!" is not enough to Prove Efficacy of an Ebola VaccineDavid R CroweA recently published Ebola vaccine trial claimed an almost perfect result with no cases of Ebola after the vaccine had time to take effect - a vaccine efficacy of 100%. This article is a detailed review of the information published about the trial and, particularly, this claim. The trial design was sub-optimal because randomization was only partial (and one treatment … …American Journal of Immunology, Vol. 13, Issue 3 · 8 Jul 2017 · 17,825 accessesView PDFCite
EditorialOpen accessIn the abstractAre we Able to Harness the Immunomodulatory Power of Cytokines for Novel Autoimmune Disease Treatments?Giuseppe Nocentini, Graziella Migliorati, Carlo RiccardiSince the end of the 1970s, interleukin 2 (IL-2) has been known as a key player in T cell expansion/activation (Watson et al., 1980). In the late 1980s, some groups used IL-2 to stimulate the immune systems of tumour patients (Jacobs et al., 1986). The idea seemed brilliant and several attempts were made, but the results were disappointing (Lim et … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 2 · 22 Oct 2015 · 7,625 accessesView PDFCite
Research ArticleOpen accessIn the abstractAlzheimer’s Disease Prognosis is Captured by a Down-Upsized Incidence Poisson DistributionRamalingam ShanmugamAlzeimer disease is a daunting nightmare to both the medical and families of the patients. Tireless efforts are made by the medical researchers to treat Alzheimer’s patients. The Alzhiemer patients’ data provides clues about its prognosis and they can be identifies when the data are analyzed and understood correctly. The data analysis is a first step in the path to … …Current Research in Medicine, Vol. 4, Issue 2 · 4 Sep 2013 · 6,926 accessesView PDFCite
Research ArticleOpen accessIn the abstractIs Cancer Recurrence Postponed By a Treatment? A New Model AnswersRamalingam ShanmugamDuring a treatment period of a cancer patient, the medical team ponders over a question: Is patient’s cancer recurrence significantly postponed by the medication, even if the illness is not completely cured? This question could be answered with data evidence if the data are analyzed with an appropriate model and a suitable methodology. A scanning of the literature reveals that … …Current Research in Medicine, Vol. 4, Issue 1 · 26 Mar 2013 · 6,887 accessesView PDFCite
Research ArticleOpen accessIn the abstractEfficacy Assessment of Kaempferia parviflora for the Management of Erectile DysfunctionPanakaporn Wannanon, Jintanaporn Wattanathorn, Terdthai Tong-Un et al.Age-related decline in erectile function is a noted phenomenon worldwide. A variety of medicinal plants have been identified as having strong aphrodisiac properties along with the ability to improve erectile functioning. Kaempferia Parviflora (KP) has famous as a Thai Viagra and use it to increase male impotency. However, there is limited scientific evidence regarding the efficacy of this herb on … …OnLine Journal of Biological Sciences, Vol. 12, Issue 4 · 4 Feb 2013 · 19,852 accessesView PDFCite