4 articles for “Phyllanthus amarus”

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Research ArticleOpen accessPhrase in the titleAn in vitro Permeation of Phyllanthus amarus Extract Through Human and Shed Snake SkinsAroonsri Priprem, S. Radapong, S. Preeprame et al.An in vitro permeation of a hydroalcoholic extract of Phyllanthus amarus (PaE) was investigated using excised human epidermis and shed king cobra skin as the barrier membranes. Donor and receptor compartments of diffusion cells were pH-controlled to simulate the permeation environment of the human skin. The PaE was analyzed by using normal-phase densitometric TLC detected at λ 280 nm and … …American Journal of Agricultural and Biological Sciences, Vol. 2, Issue 3 · 30 Sep 2007 · 7,787 accessesView PDF Cite

Research ArticleOpen accessPhrase in the titlePhyllanthus Amarus Facilitates the Recovery of Peripheral Nerve after InjuryPanakpaporn Wannannond, Jintanaporn Wattanathorn, Supaporn Muchimapura et al.Problem statement: Peripheral nerve injuries are associated with morbidity and outcomes of peripheral nerve repair are poor. Moreover, it can subsequently leads to economic or social disability. Recent findings have shown that oxidative stress plays an important role on the functional recovery retardation of peripheral nerve. However, the impairment mentioned earlier is counteracted by antioxidant. Therefore, this study was carried … …American Journal of Applied Sciences, Vol. 9, Issue 7 · 10 May 2012 · 7,098 accessesView PDF Cite

Research ArticleOpen accessIn the keywordsTherapeutic Effects of Phyllanthus Species: Induction of TNF-α-mediated Apoptosis in HepG2 Hepatocellular Carcinoma CellsSripathi M. Sureban, Dharmalingam Subramaniam, Paramasivam Rajendran et al.Phyllanthus species, especially P. amarus is a medicinal plant with hepatoprotective activity, believed to occur in part by inhibiting hepatitis B virus function. The pathogenesis mechanism of viral hepatitis is closely related to hepatocyte necrosis apoptosis. The aim of our study was to investigate the in vitro effects of extracts from three Phyllanthus species, P. urinaria, P. amarus and P. … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2007 · 9,005 accessesView PDF Cite

Research ArticleOpen accessIn the abstractReverse Pharmacology-A Paradigm Shift for Drug Discovery and DevelopmentAshok D.B. VaidyaThe current scenario of drug discovery and development is facing a model perturbation, despite significant advances in genomics, proteomics, metabolomics, combinatorial chemistry and high through put assays. There is an urgent need of a paradigm shift in approaches to drug discovery. Natural products of Ayurveda offer a vast potential for novel phytomolecules with clinical activity. In India, Ayurveda is availed … …Current Research in Drug Discovery, Vol. 1, Issue 2 · 26 Jan 2015 · 15,398 accessesView PDF Cite