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27 articles for “Peripheral blood mononuclear cell”
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Research ArticleOpen accessPhrase in the titleTHE IMMUNOMODULATORY EFFECTS OF PROBIOTIC BACTERIA ON PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) OF ALLERGIC PATIENTSSomaya M. El Sheikh, Mona A.M. Shalaby, Raghda A. Hafez et al.Allergic diseases represent major health burden. An allergic reaction is characterized by a disrupted T- helper 1⁄T-helper 2 balance toward a preferential allergen specifically induced TH2 cytokine profile, causing allergic inflammation Probiotic bacteria have various benificial effects in many pathologic situation. Studies have shown that the bacteria present in the intestinal micro flora play a role in the TH1/TH2 balance … …American Journal of Immunology, Vol. 10, Issue 3 · 10 Sep 2014 · 8,276 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleGene Expression Profiling of Toll-Like Receptor 4 and 5 in Peripheral Blood Mononuclear Cells of Patients with Systemic SclerosisSimin Almasi, Saeed Aslani, Hadi Poormoghim et al.The Toll-Like Receptor (TLR) family is appeared to be expressed in many cell types in the immune system and plays a role in the pathogenesis of various autoimmune diseases. The expression profile and role of TLRs in Systemic Sclerosis (SSc) have been partly explained. It is aimed through this investigation to evaluate the expression pattern of TLR 4 and 5 … …American Journal of Immunology, Vol. 12, Issue 1 · 17 Mar 2016 · 7,051 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleIn vitro Effects of Beet Root Juice on Stimulated and Unstimulated Peripheral Blood Mononuclear CellsChristiana Winkler, Barbara Wirleitner, Katharina Schroecksnadel et al.Intake of fruits and vegetables rich in antioxidants is suggested to reduce the incidence of cancer and coronary heart disease in humans. Exceptional antioxidant activity of beet root extracts has been reported. Likewise in animal models, e.g., extracts of red beetroot Beta vulgaris var. rubra revealed significant tumor inhibitory effects. Red beetroot concentrate is universally permitted as a food ingredient. … …American Journal of Biochemistry and Biotechnology, Vol. 1, Issue 4 · 31 Dec 2005 · 9,528 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleExtracts of Pumpkin (Cucurbita pepo L.) Seeds Suppress Stimulated Peripheral Blood Mononuclear Cells in vitroChristiana Winkler, Barbara Wirleitner, Katharaina Schroecksnadel et al.In the traditional medicine in North America and Mexico, pumpkin seeds have been used as an anthelmintic agent and for supportive treatment in functional disorders of the bladder. Also anti-inflammatory and cardioprotective activity of pumpkin seeds is discussed. Three different extracts of pumpkin seeds were prepared and effects were investigated in unstimulated human peripheral blood mononuclear cells and in cells … …American Journal of Immunology, Vol. 1, Issue 1 · 31 Mar 2005 · 10,717 accessesView PDFCite
Research ArticleOpen accessPhrase in the titleThe Flavonoid, Quercetin, Inhibits HIV-1 Infection in Normal Peripheral Blood Mononuclear CellsMadhavan P.N. Nair, Zainulabedin M. Saiyed, Nimisha H. Gandhi, C. N. RamchandProblem statement: Flavonoids and related polyphenols, have been known to possess cardioprotective, anti-tumor, anti-inflammatory, anti-allergic and anti-viral activities. Previous studies have shown that flavonoid, quercetin significantly downregulates expression of pro-inflammatory cytokines in cultured cells via modulation of NFκB and p38MAPK signaling pathways. In the current study, we hypothesize that quercetin exerts anti-HIV activity by differential modulation of pro-and anti-inflammatory cytokine … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 12,190 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMELATONIN PROTECTS THE INTEGRITY OF GASTRIC STRUCTURE FROM A STERILE TISSUE INJURY AND AUGMENTS BOTH MONONUCLEAR AND POLYMORPHONUCLEAR PERIPHERAL BLOOD CELLS INDUCED BY THE INJURY IN WISTAR ALBINO RATSBahjat Al-AniPeptic ulcer is a common upper gastrointestinal disease that remains a major public health problem. Gastric ulceration caused by Nonsteroidal Anti-Inflammatory Drugs (NSAID), stress and alcohol are the common causes of gastric ulcer formation in humans following helicobacter pylori bacterial infection of the stomach. The neurohormone, melatonin was reported to protect against NSAID- and stress-induced gastric lesions. We sought to … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 17 Mar 2014 · 7,230 accessesView PDFCite
Research ArticleOpen accessIn the keywordsCD2 Shown to Facilitate CD4+ Cell Differentiation during Visceral Leishmaniasis, a Receptor Based StudySukrat Sinha, Shanthy Sundaram, Sanjiva Bimal et al.This study addressed the role of CD2 on CD4+ T helper cells in relation to the TCRVα1 and CD70 in two groups of BALB/c mice viz control and infected (1×107 L. donovani promastigotes). The results showed with the downregulation of CD2 expression there is a pronounced decrease of TCRVα1 and CD70 on CD4+ cells in mice. An insight into the … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 28 Nov 2015 · 7,831 accessesView PDFCite
Research ArticleOpen accessIn the keywordsUnderstand the Role of Natural KillerHan Yuen Lam, Swee Keong Yeap, Noorjahan Banu Alitheen et al.Problem statement: Immunosuppression is a common approach for pathogens or cancer to escape from immune system of the infected host. Some of the antimicrobe or anticancer drugs may also weaken the body immune system. Among various types of immune cell, natural killer cells are the key component of the innate immunity which plays an important role in first line defense … …American Journal of Immunology, Vol. 6, Issue 4 · 5 Aug 2011 · 7,938 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunomodulatory and Antioxidant Activities of Selenium-Enriched Polysaccharides from Epimedium and Isatis IndigoticaRui Zhang, Jin Li, Jiajia ZhouThis study aims to investigate the effects of selenium modification on polysaccharides derived from two traditional Chinese medicinal herbs-Epimedium (Yinyanghuo) and Isatis root (Banlangen)-in enhancing immune function and antioxidant activity. The purpose is to explore the relationship between structure and function, providing a theoretical basis for the development of efficient plant-based functional antioxidants. Polysaccharides were extracted using an optimized enzymatic … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 3 Feb 2026 · 1,937 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Sled Dog Model for Positive Health Effects of Weight Management and ExerciseLaura Falkenstein, Scott Jerome et al.Obesity is a significant risk factor for metabolic syndrome and type II diabetes. Physical activity and/or dietary modification can reduce the incidence of obesity. Marginal fitness levels limit the efficacy of exercise training, and most humans choose from a wide range of dietary strategies to lose weight. Despite these limitations, exercise in the absence of weight loss may offer protective … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 1 · 23 Feb 2023 · 6,155 accessesView PDFCite