7 articles for “Off-Label”

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Review ArticleOpen accessPhrase in the titleTrazodone: A Review of Its Pharmacological Properties and Its Off-Label Use in Dogs and CatsBunna Chea, Mario GiorgiTrazodone is approved by the Food and Drug Administration (FDA) for the treatment of depression and anxiety in humans, it can perform these functions due to its selective serotonin receptor antagonism and reuptake inhibition properties. Trazodone has not been approved for animals by the FDA but it is legally prescribed by veterinarians as an off-label drug for dogs and cats. … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 4 · 31 Oct 2017 · 10,858 accessesView PDF Cite

Review ArticleOpen accessIn the keywordsNon-Steroidal Anti-Inflammatory Drugs in Food Producing AnimalsDe Vito VirginiaProviding adequate food supply to meet the demands of a growing population is a challenge for this century. The food producing animals bred in optimized conditions supply a large amount of food derivatives. At the same time, society has become progressively more concerned about animal suffering and aware of the need of pain prevention and treatments. One of the measures … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 2 · 12 Jun 2015 · 7,715 accessesView PDF Cite

Research ArticleOpen accessIn the abstractRapid Recovery of Peripheral Oxygen Saturation in Hypoxic COVID-19 Patients With Ivermectin/Doxycycline/Zinc Multidrug TherapySabine Hazan, Adriana C. Vidal, Eleftherios Gkioulekas et al.Several combination therapies for the early outpatient treatment of COVID-19 were proposed by independent research groups at the onset of the pandemic during 2020 and 2021. In this observational study, we report on the outcomes of an off-label triple combination therapy, consisting of ivermectin, doxycycline, and zinc, with adjunct vitamin C and D3 supplementation, which was used on high-risk COVID-19 … …American Journal of Infectious Diseases, Vol. 22, Issue 1 · 3 Jul 2026 · 3,374 accessesView PDF Cite

Review ArticleOpen accessIn the abstractGabapentin in Cattle: A Pharmacology SnapshotCharbel Fadel, Irene Sartini, Mario GiorgiGabapentin (GBP) is an antiepileptic and analgesic drug that is derived from gamma-aminobutyric acid. It is used as an analgesic in multi-modal pain management, as well as an anticonvulsant and anxiolytic, off-label in animals. Particularly, oral GBP prescriptions for cattle are becoming increasingly popular. Since its introduction into cattle farm practices, several types of research on GBP in cattle have … …American Journal of Animal and Veterinary Sciences, Vol. 17, Issue 3 · 29 Jul 2022 · 7,821 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAnalytical Method Validation of Vilazodone with Spectrofluorimetric Detection in Rabbit PlasmaIrene Sartini, Marco Salvadori, Beata Łebkowska-Wieruszewska et al.Vilazodone (VLZ) is an antidepressant agent approved in 2011 by Food and Drug Administration (FDA) for the treatment of major depressive syndromes. Its chemical structure derives from trazodone which is used as an off-label drug for dogs and cats in order to induce sedation and reduce anxiety, behavioural and pre-and post-operative stress. VLZ could be a potentially useful compound in … …American Journal of Animal and Veterinary Sciences, Vol. 14, Issue 1 · 2 Apr 2019 · 7,740 accessesView PDF Cite

Research ArticleOpen accessIn the abstractMisbehaving Node Detection in Mobile Ad Hoc Networks using Multi Hop Acknowledgement SchemeUsha Sakthivel, S. RadhaProblem statement: For any node in a Mobile Ad hoc Network conservation of battery power and bandwidth are the priority. Hence, they try to reduce the overload they would otherwise incur when they forward packets. This selfish behavior of a node affects the throughput of the network. The nodes may also choose a back off value of shorter duration. These … …Journal of Computer Science, Vol. 7, Issue 5 · 7 May 2011 · 6,712 accessesView PDF Cite

Research ArticleOpen accessIn the abstractMULTI SCALE TIME SERIES PREDICTION FOR INTRUSION DETECTIONG. Palanivel, K. DuraiswamyWe propose an anomaly-based network intrusion detection system, which analyzes traffic features to detect anomalies. The proposed system can be used both in online as well as off-line mode for detecting deviations from the expected behavior. Although our approach uses network packet or flow data, it is general enough to be adaptable for use with any other network variable, which … …American Journal of Applied Sciences, Vol. 11, Issue 8 · 27 Jun 2014 · 6,776 accessesView PDF Cite