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21 articles for “Non-Antibiotic”
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Research ArticleOpen accessPhrase in the titleNon-Antibiotic Immunomodulatory Combination Treatment for Staphylococcus aureus Infections: In vitro Preliminary Studies IJatna Isha Rivas Zarete, Dominique Lyles, Benjamin Adu-AddaiDespite advancements in prevention measures, infectious mastitis is a common disease of economic significance in cattle. Clinical mastitis affects 20 to 25% of cows each year. Staphylococcus aureus (S. aureus) causes an estimated 10-11.7% of clinical bovine infectious mastitis cases in the US. Antibiotic therapy tends to fail 50% of the time and nature and vaccine immunity usually fails, due … …American Journal of Infectious Diseases, Vol. 18, Issue 4 · 14 Feb 2023 · 5,677 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEffects of Flavomycin on Ruminal Fermentation, In Situ Degradability and In Vivo Digestibility in Bovine Fed Sugarcane DietsS.M. Mogentale, E.J.A. Silva, P.M. Meyer et al.Problem statement: The aim of the present study was to characterize and differentiate the effects of addition of flavomycin or monensin on ruminal fermentation and degradability as well as on total digestibility in bovine. Approach: Twelve non-pregnant and non-lactating cows (736 kg of BW) were randomly assigned to three treatments: control, flavomycin (20 mg animal-1 day-1) and monensin (300 mg … …American Journal of Animal and Veterinary Sciences, Vol. 5, Issue 2 · 30 Jun 2010 · 8,370 accessesView PDFCite
Research ArticleOpen accessIn the keywordsSulfa Allergy: Cross-Reactivity Versus Multiple Concurrent AllergiesMuhammad Tariq Shakoor, Samia Ayub, Zunaira AyubAs a medical resident we have always been taught that there is some sort of cross reactivity between sulfonamide antibiotics and nonantibiotic sulfonamides. Even the manufacturer’s package inserts contain a precautionary statement about possible Cross-reactivity. The most common approach to this problem is avoidance of all sulfa containing drugs. However, there are few data supporting this contraindication. Thus we may … …American Journal of Infectious Diseases, Vol. 9, Issue 4 · 2 Dec 2013 · 9,629 accessesView PDFCite
Research ArticleOpen accessIn the abstractDominant Multidrug-Resistant Bacteria in Five Biggest Hospitals in Asir Region from March to June 2018Mohammed AlmaghrabiThere is a rapid increase in the emergence of multidrug resistance which consider as one of the public health threats in all over the world. MDR was defined as acquired non-susceptibility to at least one agent in three or more antimicrobial categories. The present study aims to determine the dominant multi-drug resistant bacteria in the five biggest hospitals in Asir … …American Journal of Infectious Diseases, Vol. 17, Issue 1 · 9 Mar 2021 · 6,782 accessesView PDFCite
Review ArticleOpen accessIn the abstractDrug Repositioning in Response to COVID-19 and other Challenging DiseasesHyellavala Joseph Fomnya, Saidu Ibrahim Ngulde, Sarah Malgwi Gana et al.Coronavirus disease is a highly contagious infection that is majorly associated with upper respiratory tract illnesses. The World Health Organization (WHO) label the novel coronavirus disease COVID-19 after an epidemic of the disease in Wuhan, Hubei province (China). Over 90 clinical trials, including drug repositioning, have been initiated to get COVID-19 treatment/management. Antibiotic resistance, drug tolerance, mutation, and adverse drug … …American Journal of Pharmacology and Toxicology, Vol. 17, Issue 1 · 28 Nov 2022 · 9,503 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Proven Viral Load on Common Cold Patients Treated with Pelargonium sidoides Preparation EPs 7630Tilman Keck, Andreas Strobl, Andreas Weinhaeusel, Berenike StrackeThe Common Cold (CC) is an acute respiratory tract disorder with viral etiology in at least 90% of the cases. Nevertheless, molecular diagnostic testing often confirms the presence of viral Nucleic Acids (NA) in only about half of the patients. Based on the results of a non-comparative, interventional multicenter study we compare the course of CC between patients with and … …American Journal of Infectious Diseases, Vol. 14, Issue 3 · 13 Nov 2018 · 8,402 accessesView PDFCite
Research ArticleOpen accessIn the abstractUTILITY OF A COMBINATION ANTIBIOGRAM FOR TREATING PSEUDOMONAS AERUGINOSALindsay Thurman, Nathan Fewel, Michael Rose, Eileen StockEmpiric combination antibiotic therapy is often used to treat severe P. aeruginosa infections. Combination antibiograms have been employed to assist clinicians in selecting the most effective two-drug antibiotic regimens. The objectives of this study were to develop a combination antibiogram in order to compare beta-lactam monotherapy versus dual-therapy with a fluoroquinolone or aminoglycoside, identify optimal combination regimens, describe the differences … …American Journal of Infectious Diseases, Vol. 10, Issue 2 · 16 Jun 2014 · 8,970 accessesView PDFCite
Research ArticleOpen accessIn the abstractINHIBITORY ACTIVITY OF POTENTOX AGAINST DNA GYRASE OF ENTEROBACTERIACEAEManu Chaudhary, Anurag PayasiDNA gyrase, a type II topoisomerase catalyzes the supercoiling of relaxed closed circular DNA. In this report we evaluated the in vitro inhibitory effect of non antibiotic adjuvant compounds disodium edetate and sodium citrate against supercoiling activity of bacterial DNA gyrase. Further, we assessed the effect of different drugs alone and in combination with one or more adjuvants in overcoming … …American Journal of Infectious Diseases, Vol. 10, Issue 1 · 8 Feb 2014 · 7,288 accessesView PDFCite
Research ArticleOpen accessIn the abstractSYNERGY OF A NOVEL ANTIBIOTIC ADJUVANT ENTITY AGAINST MULTI DRUG RESISTANT ENTEROBACTERIACEAEManu Chaudhary, Anurag PayasiIn the present investigation, we investigated the in vitro interaction of ceftriaxone plus sulbactam with disodium edetate, a Non Antibiotic Adjuvant (NAA) against selected clinical isolates and in vitro susceptibility studies were also performed. The isolates were tested against a range of ratios of ceftriaxone and sulbactam using a microdilution checkerboard method. Having determined the appropriate ratios of ceftriaxone plus … …American Journal of Infectious Diseases, Vol. 9, Issue 3 · 1 Nov 2013 · 7,416 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibiogram of Bacteria Isolated from Kunun-Zaki Drink Sold in Keffi MetropolisMakwin Danladi Makut, Mary Azumi Nyam, Smart Obumneme Obiekezie, Aisha Eleojo AbubakarKunun-zaki drink is a locally prepared indigenous non-alcoholic beverage that is widely produced and consumed in Nigeria. Standard microbiological methods were employed to isolate bacteria from Kunun-zaki drink sold in Keffi metropolis, Nasarawa State, Nigeria. Samples of Kunun-zaki drink were collected from ten (10) different locations and their bacteriological loads were determined in terms of total bacterial counts using standard … …American Journal of Infectious Diseases, Vol. 9, Issue 3 · 9 Sep 2013 · 8,461 accessesView PDFCite