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7 articles for “Melatonin”

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Research ArticleOpen accessEvery word in the titleEvidences for the Role of Melatonin as a Protective Additive During Buffalo Semen FreezingMohamed El-Raey, M. R. Badr, Z. M. Rawash, G. M. DarwishTill now, the exact role of melatonin in male infertility hasn’t been fully discovered. Moreover, the intracellular signaling pathways activated by melatonin in buffalo spermatozoa especially on the level of cryopreservation process haven’t been reported. The current study aimed simply to clarify the precise role of this hormone during buffalo semen cryopreservation. Semen samples were obtained randomly from 6 fertile … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 23 Dec 2014 · 8,112 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMELATONIN PROTECTS THE INTEGRITY OF GASTRIC STRUCTURE FROM A STERILE TISSUE INJURY AND AUGMENTS BOTH MONONUCLEAR AND POLYMORPHONUCLEAR PERIPHERAL BLOOD CELLS INDUCED BY THE INJURY IN WISTAR ALBINO RATSBahjat Al-AniPeptic ulcer is a common upper gastrointestinal disease that remains a major public health problem. Gastric ulceration caused by Nonsteroidal Anti-Inflammatory Drugs (NSAID), stress and alcohol are the common causes of gastric ulcer formation in humans following helicobacter pylori bacterial infection of the stomach. The neurohormone, melatonin was reported to protect against NSAID- and stress-induced gastric lesions. We sought to … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 17 Mar 2014 · 7,227 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleProphylactic Effects of Melatonin on Sodium Valproate-Induced Neural Tube Defects and Skeletal Malformations in Rat EmbryosOmolbanin Rahgazar, Reza Ranjbar, Hossien Najafzadeh Varzi, Mahmood Khaksary MahabadyProblem statement: Some reports showed the teratogenic effects of sodium valproate can be prevented by application of antioxidant drugs and stimulation of the maternal immune system. Therefore, in this study, the prophylactic effect of melatonin on teratogenic effects of sodium valproate was compared. Approach: This study was performed on 31 pregnant rats that were divided into five groups. Control group … …American Journal of Applied Sciences, Vol. 8, Issue 5 · 17 May 2011 · 7,281 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffects of Melatonin in Prevention of Neuropathy in STZ-Induced Diabetic RatsNasser Zangiabadi, Vahid Sheibani, Majid Asadi-Shekaari et al.Problem statement: Diabetes mellitus occurs mainly with chronic polyneuropathy, and oxidative stress plays an important role in emergence of most neurologic and behavioral changes in diabetic patients. Many studies have focused on the beneficial effects of various antioxidants such as melatonin on diabetic neuropathy. The aim of this study is to evaluate the effect of melatonin in prevention of neuropathy … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 2 · 17 Sep 2011 · 9,358 accessesView PDFCite
Research ArticleOpen accessIn the abstractUltrastructural and Circadian Morphometric Characteristics of Rat Pinealocytes Under Physiological and Toxic ConditionsAnna I. Anurkina, David A. Areshidze, Maria A. Kozlova, Valery P. ChernikovCarbon tetrachloride (CCl₄) exhibits pronounced neurotoxic effects following acute or chronic exposure. Recent studies indicate that the pineal gland responds to CCl₄ intoxication by altering its secretory function, although detailed ultrastructural changes in pinealocytes remain inadequately investigated. This research addresses the urgent need to elucidate the mechanisms of CCl₄ toxicity on the pineal gland, which could contribute to developing strategies … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 1 Jun 2026 · 1,170 accessesView PDFCite
Research ArticleOpen accessIn the abstractBioactive Factors of Colostrum and Human Milk Exhibits a Day-Night VariationNubia Andrade Silva, Adenilda Cristina Honorio-Franca, Fernanda Regina Giachini et al.The aim of this study was to determine the chronobiological variations of cytokines (IFN-γ, TGF-β) and hormones (melatonin and cortisol). The sample was collected from 42 mothers at three stages of maturity-day 3 (colostrum), day 10 (transitional milk) and day 30 (mature milk) postpartum, at two times of day: diurnal (12:00 h) and nocturnal (24:00 h), resulting a total of … …American Journal of Immunology, Vol. 9, Issue 2 · 25 Jun 2013 · 8,186 accessesView PDFCite
Research ArticleOpen accessIn the abstractNutritional Supplements and its Effect on Quality of Life and SleepSara Sarrafi Zadeh, Khyrunnisa BegumProblem statement: Inadequate sleep has been recognized as a risk factor for poor health status. Mental stress, body pains, melatonin deficiency, late night awakening disturbing the body clock are triggers for poor quality of sleep and fatigue. Fatigue due to insomnia is a major cause for poor quality of life. Evidences suggest certain nutrients to exert profound influence on quality … …Current Research in Medicine, Vol. 2, Issue 2 · 1 Dec 2011 · 9,258 accessesView PDFCite