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26 articles for “Malignant Tumor”
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Research ArticleOpen accessPhrase in the titleQuantitative Analysis of Hypothalamic Proline-Rich Peptide-1 in Blood Serum of Patients with Malignant TumorsNarine Tumasyan, Silva Abrahamyan, Nune Kocharyan et al.The proline-rich-peptides are a class of neurosecretory hypothalamic bioactive polypeptides derived from cattle and comprise the content of bovine posterior pituitary neurosecretory granules. These peptides are co-validated through a single precursor protein neurophysin-vasopressin-associated glycoprotein. Proline-Rich-Polypeptide-1 (PRP-1) is a 15-amino acid peptide with anti-neurodegenerative, immunoregulatory, hematopoietic, antimicrobial, and antitumor activity. The aim of this study, accordingly, is to elaborate an assay … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 27 Nov 2025 · 2,283 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMast Cells Inhibit CD8+ T Cell-Mediated Rejection of a Malignant Fibrous Histiocytoma-Like Tumor: Involvement of Fas-Fas Ligand AxisHiroshi Furukawa, Hiroshi Kitazawa, Izumi Kaneko et al.Problem statement: Mast cells develop from bone marrow-derived progenitor cells and are distributed in the skin or mucosa where they play proinflammatory roles in the first line of defense. Since some tumors in humans and experimental animals exhibited infiltration of increased mast cells, we investigated the contribution of mast cells to the override of tumor rejection. Approach: MRL/N-1 cells are … …American Journal of Immunology, Vol. 5, Issue 3 · 30 Sep 2009 · 7,670 accessesView PDFCite
Research ArticleOpen accessIn the keywordsCorrelation of Some Biochemical Parameters between Serum and Saliva of Patients with Breast CancerOmar Atrooz, Huthaifa TarawnehRegular breast cancer laboratory examination of serum is aburden on patients, therefore understanding salivary test methods' featuresand limits is important for diagnosis. The study aims to evaluate thebiochemical parameters in the serum and saliva of breast cancer and controlindividuals. Furthermore, to investigate the correlation between two biofluidlevels in both groups. This cross-sectional study recruited Jordanian femalesincluding 40 breast cancer patients … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 20 May 2025 · 4,487 accessesView PDFCite
Research ArticleOpen accessIn the abstractCuckoo Search Optimized Random Forest for Breast Cancer PrognosisPrasad S. Sase, Debabrata Swain, Shailesh KumarBreast cancer remains a major global health concern due to its high mortality rate, particularly when diagnosis occurs at an advanced stage. Accurate and early differentiation between benign and malignant tumors is therefore critical for improving patient outcomes. Conventional diagnostic practices largely depend on manual assessment and clinical expertise, which may lead to subjective variability in decision-making. To overcome this … …Journal of Computer Science, Vol. 22, Issue 1 · 31 Jan 2026 · 2,098 accessesView PDFCite
Research ArticleOpen accessIn the abstractDihydroartemisinin Attenuates HBV-Induced Proliferation and Migration in LO2 cells via EMT Pathway ModulationYingde Nong, Caifang Ma, Wei Huang et al.Dihydroartemisinin (DHA), a derivative of artemisinin, possesses well-documented anti-inflammatory properties. This study investigated the inhibitory effects of DHA on hepatitis B virus (HBV)-induced cellular alterations in LO2 cells and elucidated underlying molecular mechanisms. Serum interleukin-6 (IL-6) levels were measured in HBV patients and analyzed for correlations with HBsAg, anti-HBs, and HBeAg. In vitro, LO2 cells were infected with clinical HBV … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 8 Jan 2026 · 2,071 accessesView PDFCite
Research ArticleOpen accessIn the abstractRelationship between Streptococcus gallolyticus Infective Endocarditis and Pre-Neoplastic Colorectal LesionsPau Vilardell, Sergio Moral, Josep Maria Frigola et al.Colorectal cancer is associated with Infective Endocarditis (IE) due to specific gut pathogens, such as Streptococcus gallolyticus subspecies, that use tumor presence as a point of blood entry. However, the association between Streptococcus gallolyticus related IE and pre-cancerous colorectal lesions like dysplastic adenomas is unclear. Seventy-one patients diagnosed with IE who underwent colonoscopy in the extension study during admission were … …American Journal of Infectious Diseases, Vol. 17, Issue 3 · 28 May 2021 · 7,131 accessesView PDFCite
Research ArticleOpen accessIn the abstractIdentification of Cancer: Mesothelioma’s Disease Using Logistic Regression and Association RuleAvishek ChoudhuryMalignant Pleural Mesothelioma (MPM) or malignant mesothelioma (MM) is an atypical, aggressive tumor that matures into cancer in the pleura, a stratum of tissue bordering the lungs. Diagnosis of MPM is difficult and it accounts for about seventy-five percent of all mesothelioma diagnosed yearly in the United States of America. Being a fatal disease, early identification of MPM is crucial … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 4 · 7 Dec 2018 · 7,224 accessesView PDFCite
Research ArticleOpen accessIn the abstractRelative Transcription Expression Level of SIRT1, SIRT2 and SIRT3 in Correlation to the Expression of a Set of Selected Cancer Related Genes in Human Breast CancerHamdy Swelim, Omnia Mansour, Salah Abdel-Rahman et al.Mammalian Sirtuins have been shown to perform distinct cellular functions and deregulated expression of these genes was reported to be involved in the development of various malignancies including breast cancer. An increasing number of evidence indicates that Sirtuins have both tumor promoter and tumor suppressor functions. However, the roles of Sirtuins have not been well-studied in breast cancer. In the … …OnLine Journal of Biological Sciences, Vol. 18, Issue 2 · 18 Jan 2018 · 7,476 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrevalence and Histopathologic Analyses of Mammary Tumors in Female Dogs in the Northeast of AlgeriaZahra GABLI, Leila BEDDAR, Amir Agabou et al.Cancers development and complications are a major cause of death in dogs all over the world. The current study attempts to describe the prevalence and anatomo-pathologic traits of mammary gland tumors (MGTs) in bitches in northeast Algeria. From November 2013 to April 2016, a total of 215 bitches originating from four provinces (Constantine, Oum El Bouaghi, Annaba and Skikda) were … …OnLine Journal of Biological Sciences, Vol. 17, Issue 3 · 26 Sep 2017 · 7,546 accessesView PDFCite
Case ReportOpen accessIn the abstractIntestinal Mucinous Adenocarcinoma with Lymph Node Metastasis in a CatHandan Hilal Arslan, Hatice Ozlem Nisbet, Efe Karaca et al.Intestinal adenocarcinoma is a malignant tumor. The most common clinical signs of gastrointestinal adenocarcinoma are depression, anorexia, loss of weight, vomiting, diarrhea or constipation due to obstruction. In cats, gastrointestinal adenocarcinomas are the most common non-hematopoietic gastrointestinal tumors and their frequency is higher in males. In this report, the case of an 8 year old male cat with adenocarcinoma that … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 3 · 17 Aug 2017 · 8,893 accessesView PDFCite